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AMY2B (amylase, alpha 2B (pancreatic))

Identity

Alias_namesAMY2
amylase, alpha 2B; pancreatic
Other aliasAMY3
HXA
HGNC (Hugo) AMY2B
LocusID (NCBI) 280
Atlas_Id 60283
Location 1p21.1  [Link to chromosome band 1p21]
Location_base_pair Starts at 103554644 and ends at 103579534 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CADPS (3p14.2) / AMY2B (1p21.1)PCK1 (20q13.31) / AMY2B (1p21.1)PPP4R3B (2p16.1) / AMY2B (1p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AMY2B   478
Cards
Entrez_Gene (NCBI)AMY2B  280  amylase, alpha 2B (pancreatic)
AliasesAMY2; AMY3; HXA
GeneCards (Weizmann)AMY2B
Ensembl hg19 (Hinxton)ENSG00000240038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000240038 [Gene_View]  chr1:103554644-103579534 [Contig_View]  AMY2B [Vega]
ICGC DataPortalENSG00000240038
TCGA cBioPortalAMY2B
AceView (NCBI)AMY2B
Genatlas (Paris)AMY2B
WikiGenes280
SOURCE (Princeton)AMY2B
Genetics Home Reference (NIH)AMY2B
Genomic and cartography
GoldenPath hg38 (UCSC)AMY2B  -     chr1:103554644-103579534 +  1p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AMY2B  -     1p21.1   [Description]    (hg19-Feb_2009)
EnsemblAMY2B - 1p21.1 [CytoView hg19]  AMY2B - 1p21.1 [CytoView hg38]
Mapping of homologs : NCBIAMY2B [Mapview hg19]  AMY2B [Mapview hg38]
OMIM104660   
Gene and transcription
Genbank (Entrez)AI436349 AK095605 AK127047 BC011179 BC020861
RefSeq transcript (Entrez)NM_020978
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AMY2B
Cluster EST : UnigeneHs.484588 [ NCBI ]
CGAP (NCI)Hs.484588
Alternative Splicing GalleryENSG00000240038
Gene ExpressionAMY2B [ NCBI-GEO ]   AMY2B [ EBI - ARRAY_EXPRESS ]   AMY2B [ SEEK ]   AMY2B [ MEM ]
Gene Expression Viewer (FireBrowse)AMY2B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)280
GTEX Portal (Tissue expression)AMY2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19961   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19961  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19961
Splice isoforms : SwissVarP19961
PhosPhoSitePlusP19961
Domains : Interpro (EBI)A-amylase/branching_C    A-amylase_C    Alpha_amylase    Glyco_hydro_13_cat_dom    Glyco_hydro_b    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Alpha-amylase (PF00128)    Alpha-amylase_C (PF02806)   
Domain families : Pfam (NCBI)pfam00128    pfam02806   
Domain families : Smart (EMBL)Aamy (SM00642)  Aamy_C (SM00632)  
Conserved Domain (NCBI)AMY2B
DMDM Disease mutations280
Blocks (Seattle)AMY2B
SuperfamilyP19961
Human Protein AtlasENSG00000240038
Peptide AtlasP19961
HPRD00095
IPIIPI00021447   IPI01010323   
Protein Interaction databases
DIP (DOE-UCLA)P19961
IntAct (EBI)P19961
FunCoupENSG00000240038
BioGRIDAMY2B
STRING (EMBL)AMY2B
ZODIACAMY2B
Ontologies - Pathways
QuickGOP19961
Ontology : AmiGOalpha-amylase activity  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Ontology : EGO-EBIalpha-amylase activity  carbohydrate metabolic process  digestion  metal ion binding  extracellular exosome  
Pathways : KEGGStarch and sucrose metabolism    Pancreatic secretion    Carbohydrate digestion and absorption   
NDEx NetworkAMY2B
Atlas of Cancer Signalling NetworkAMY2B
Wikipedia pathwaysAMY2B
Orthology - Evolution
OrthoDB280
GeneTree (enSembl)ENSG00000240038
Phylogenetic Trees/Animal Genes : TreeFamAMY2B
HOVERGENP19961
HOGENOMP19961
Homologs : HomoloGeneAMY2B
Homology/Alignments : Family Browser (UCSC)AMY2B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAMY2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AMY2B
dbVarAMY2B
ClinVarAMY2B
1000_GenomesAMY2B 
Exome Variant ServerAMY2B
ExAC (Exome Aggregation Consortium)AMY2B (select the gene name)
Genetic variants : HAPMAP280
Genomic Variants (DGV)AMY2B [DGVbeta]
DECIPHERAMY2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAMY2B 
Mutations
ICGC Data PortalAMY2B 
TCGA Data PortalAMY2B 
Broad Tumor PortalAMY2B
OASIS PortalAMY2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAMY2B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAMY2B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AMY2B
DgiDB (Drug Gene Interaction Database)AMY2B
DoCM (Curated mutations)AMY2B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AMY2B (select a term)
intoGenAMY2B
Cancer3DAMY2B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104660   
Orphanet
MedgenAMY2B
Genetic Testing Registry AMY2B
NextProtP19961 [Medical]
TSGene280
GENETestsAMY2B
Target ValidationAMY2B
Huge Navigator AMY2B [HugePedia]
snp3D : Map Gene to Disease280
BioCentury BCIQAMY2B
ClinGenAMY2B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD280
Chemical/Pharm GKB GenePA24785
Clinical trialAMY2B
Miscellaneous
canSAR (ICR)AMY2B (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAMY2B
EVEXAMY2B
GoPubMedAMY2B
iHOPAMY2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:38:01 CEST 2017

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