Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ANAPC1 (anaphase promoting complex subunit 1)

Identity

Alias_symbol (synonym)MCPR
TSG24
APC1
Other alias
HGNC (Hugo) ANAPC1
LocusID (NCBI) 64682
Atlas_Id 47289
Location 2q13  [Link to chromosome band 2q13]
Location_base_pair Starts at 112525214 and ends at 112641741 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANAPC1 (2q13) / CLK1 (2q33.1)ANAPC1 (2q13) / PSMB7 (9q33.3)ANAPC1 (2q13) / RGPD3 (2q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANAPC1   19988
Cards
Entrez_Gene (NCBI)ANAPC1  64682  anaphase promoting complex subunit 1
AliasesAPC1; MCPR; TSG24
GeneCards (Weizmann)ANAPC1
Ensembl hg19 (Hinxton)ENSG00000153107 [Gene_View]  chr2:112525214-112641741 [Contig_View]  ANAPC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000153107 [Gene_View]  chr2:112525214-112641741 [Contig_View]  ANAPC1 [Vega]
ICGC DataPortalENSG00000153107
TCGA cBioPortalANAPC1
AceView (NCBI)ANAPC1
Genatlas (Paris)ANAPC1
WikiGenes64682
SOURCE (Princeton)ANAPC1
Genetics Home Reference (NIH)ANAPC1
Genomic and cartography
GoldenPath hg19 (UCSC)ANAPC1  -     chr2:112525214-112641741 -  2q13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANAPC1  -     2q13   [Description]    (hg38-Dec_2013)
EnsemblANAPC1 - 2q13 [CytoView hg19]  ANAPC1 - 2q13 [CytoView hg38]
Mapping of homologs : NCBIANAPC1 [Mapview hg19]  ANAPC1 [Mapview hg38]
OMIM608473   
Gene and transcription
Genbank (Entrez)AI421643 AJ278357 AK023807 AK094527 AL832013
RefSeq transcript (Entrez)NM_022662
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929304
Consensus coding sequences : CCDS (NCBI)ANAPC1
Cluster EST : UnigeneHs.436527 [ NCBI ]
CGAP (NCI)Hs.436527
Alternative Splicing GalleryENSG00000153107
Gene ExpressionANAPC1 [ NCBI-GEO ]   ANAPC1 [ EBI - ARRAY_EXPRESS ]   ANAPC1 [ SEEK ]   ANAPC1 [ MEM ]
Gene Expression Viewer (FireBrowse)ANAPC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64682
GTEX Portal (Tissue expression)ANAPC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H1A4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H1A4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H1A4
Splice isoforms : SwissVarQ9H1A4
PhosPhoSitePlusQ9H1A4
Domains : Interpro (EBI)Apc1   
Domain families : Pfam (Sanger)ANAPC1 (PF12859)   
Domain families : Pfam (NCBI)pfam12859   
Conserved Domain (NCBI)ANAPC1
DMDM Disease mutations64682
Blocks (Seattle)ANAPC1
PDB (SRS)4UI9    5A31   
PDB (PDBSum)4UI9    5A31   
PDB (IMB)4UI9    5A31   
PDB (RSDB)4UI9    5A31   
Structural Biology KnowledgeBase4UI9    5A31   
SCOP (Structural Classification of Proteins)4UI9    5A31   
CATH (Classification of proteins structures)4UI9    5A31   
SuperfamilyQ9H1A4
Human Protein AtlasENSG00000153107
Peptide AtlasQ9H1A4
HPRD09769
IPIIPI00033907   IPI00917588   IPI00917383   
Protein Interaction databases
DIP (DOE-UCLA)Q9H1A4
IntAct (EBI)Q9H1A4
FunCoupENSG00000153107
BioGRIDANAPC1
STRING (EMBL)ANAPC1
ZODIACANAPC1
Ontologies - Pathways
QuickGOQ9H1A4
Ontology : AmiGOnucleoplasm  anaphase-promoting complex  cytosol  mitotic nuclear division  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Ontology : EGO-EBInucleoplasm  anaphase-promoting complex  cytosol  mitotic nuclear division  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Pathways : KEGGCell cycle    Oocyte meiosis    Ubiquitin mediated proteolysis    Progesterone-mediated oocyte maturation    HTLV-I infection   
NDEx NetworkANAPC1
Atlas of Cancer Signalling NetworkANAPC1
Wikipedia pathwaysANAPC1
Orthology - Evolution
OrthoDB64682
GeneTree (enSembl)ENSG00000153107
Phylogenetic Trees/Animal Genes : TreeFamANAPC1
HOVERGENQ9H1A4
HOGENOMQ9H1A4
Homologs : HomoloGeneANAPC1
Homology/Alignments : Family Browser (UCSC)ANAPC1
Gene fusions - Rearrangements
Fusion : MitelmanANAPC1/RGPD3 [2q13/2q12.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANAPC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANAPC1
dbVarANAPC1
ClinVarANAPC1
1000_GenomesANAPC1 
Exome Variant ServerANAPC1
ExAC (Exome Aggregation Consortium)ANAPC1 (select the gene name)
Genetic variants : HAPMAP64682
Genomic Variants (DGV)ANAPC1 [DGVbeta]
DECIPHER (Syndromes)2:112525214-112641741  ENSG00000153107
CONAN: Copy Number AnalysisANAPC1 
Mutations
ICGC Data PortalANAPC1 
TCGA Data PortalANAPC1 
Broad Tumor PortalANAPC1
OASIS PortalANAPC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANAPC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANAPC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANAPC1
DgiDB (Drug Gene Interaction Database)ANAPC1
DoCM (Curated mutations)ANAPC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANAPC1 (select a term)
intoGenANAPC1
Cancer3DANAPC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608473   
Orphanet
MedgenANAPC1
Genetic Testing Registry ANAPC1
NextProtQ9H1A4 [Medical]
TSGene64682
GENETestsANAPC1
Huge Navigator ANAPC1 [HugePedia]
snp3D : Map Gene to Disease64682
BioCentury BCIQANAPC1
ClinGenANAPC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64682
Chemical/Pharm GKB GenePA134907013
Clinical trialANAPC1
Miscellaneous
canSAR (ICR)ANAPC1 (select the gene name)
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANAPC1
EVEXANAPC1
GoPubMedANAPC1
iHOPANAPC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:52:19 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.