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ANAPC11 (anaphase promoting complex subunit 11)

Identity

Alias_namesanaphase promoting complex subunit 11 (yeast APC11 homolog)
Alias_symbol (synonym)HSPC214
APC11
Apc11p
MGC882
Other alias
HGNC (Hugo) ANAPC11
LocusID (NCBI) 51529
Atlas_Id 60288
Location 17q25.3  [Link to chromosome band 17q25]
Location_base_pair Starts at 79849589 and ends at 79858409 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANAPC11   14452
Cards
Entrez_Gene (NCBI)ANAPC11  51529  anaphase promoting complex subunit 11
AliasesAPC11; Apc11p; HSPC214
GeneCards (Weizmann)ANAPC11
Ensembl hg19 (Hinxton)ENSG00000141552 [Gene_View]  chr17:79849589-79858409 [Contig_View]  ANAPC11 [Vega]
Ensembl hg38 (Hinxton)ENSG00000141552 [Gene_View]  chr17:79849589-79858409 [Contig_View]  ANAPC11 [Vega]
ICGC DataPortalENSG00000141552
TCGA cBioPortalANAPC11
AceView (NCBI)ANAPC11
Genatlas (Paris)ANAPC11
WikiGenes51529
SOURCE (Princeton)ANAPC11
Genetics Home Reference (NIH)ANAPC11
Genomic and cartography
GoldenPath hg19 (UCSC)ANAPC11  -     chr17:79849589-79858409 +  17q25.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANAPC11  -     17q25.3   [Description]    (hg38-Dec_2013)
EnsemblANAPC11 - 17q25.3 [CytoView hg19]  ANAPC11 - 17q25.3 [CytoView hg38]
Mapping of homologs : NCBIANAPC11 [Mapview hg19]  ANAPC11 [Mapview hg38]
OMIM614534   
Gene and transcription
Genbank (Entrez)AA356010 AF151048 AF247565 AF247789 AI356704
RefSeq transcript (Entrez)NM_001002244 NM_001002245 NM_001002246 NM_001002247 NM_001002248 NM_001002249 NM_001289414 NM_001289415 NM_001289416 NM_001289417 NM_001289418 NM_001289419 NM_001289420 NM_016476
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010663 NW_004929408
Consensus coding sequences : CCDS (NCBI)ANAPC11
Cluster EST : UnigeneHs.534456 [ NCBI ]
CGAP (NCI)Hs.534456
Alternative Splicing GalleryENSG00000141552
Gene ExpressionANAPC11 [ NCBI-GEO ]   ANAPC11 [ EBI - ARRAY_EXPRESS ]   ANAPC11 [ SEEK ]   ANAPC11 [ MEM ]
Gene Expression Viewer (FireBrowse)ANAPC11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51529
GTEX Portal (Tissue expression)ANAPC11
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NYG5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NYG5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NYG5
Splice isoforms : SwissVarQ9NYG5
PhosPhoSitePlusQ9NYG5
Domaine pattern : Prosite (Expaxy)ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)Apc11    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)zf-Apc11 (PF12861)   
Domain families : Pfam (NCBI)pfam12861   
Domain families : Smart (EMBL)RING (SM00184)  
Conserved Domain (NCBI)ANAPC11
DMDM Disease mutations51529
Blocks (Seattle)ANAPC11
PDB (SRS)2MT5    4R2Y   
PDB (PDBSum)2MT5    4R2Y   
PDB (IMB)2MT5    4R2Y   
PDB (RSDB)2MT5    4R2Y   
Structural Biology KnowledgeBase2MT5    4R2Y   
SCOP (Structural Classification of Proteins)2MT5    4R2Y   
CATH (Classification of proteins structures)2MT5    4R2Y   
SuperfamilyQ9NYG5
Human Protein AtlasENSG00000141552
Peptide AtlasQ9NYG5
HPRD12452
IPIIPI00787159   IPI00000722   
Protein Interaction databases
DIP (DOE-UCLA)Q9NYG5
IntAct (EBI)Q9NYG5
FunCoupENSG00000141552
BioGRIDANAPC11
STRING (EMBL)ANAPC11
ZODIACANAPC11
Ontologies - Pathways
QuickGOQ9NYG5
Ontology : AmiGOmitotic cell cycle  ubiquitin-protein transferase activity  nucleoplasm  nucleoplasm  anaphase-promoting complex  nucleolus  cytosol  mitotic nuclear division  mitotic spindle assembly checkpoint  zinc ion binding  protein ubiquitination  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  ubiquitin-ubiquitin ligase activity  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  positive regulation of mitotic metaphase/anaphase transition  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  ubiquitin protein ligase activity  protein K11-linked ubiquitination  cullin family protein binding  
Ontology : EGO-EBImitotic cell cycle  ubiquitin-protein transferase activity  nucleoplasm  nucleoplasm  anaphase-promoting complex  nucleolus  cytosol  mitotic nuclear division  mitotic spindle assembly checkpoint  zinc ion binding  protein ubiquitination  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  ubiquitin-ubiquitin ligase activity  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  positive regulation of mitotic metaphase/anaphase transition  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  ubiquitin protein ligase activity  protein K11-linked ubiquitination  cullin family protein binding  
Pathways : KEGGCell cycle    Oocyte meiosis    Ubiquitin mediated proteolysis    Progesterone-mediated oocyte maturation    HTLV-I infection   
NDEx NetworkANAPC11
Atlas of Cancer Signalling NetworkANAPC11
Wikipedia pathwaysANAPC11
Orthology - Evolution
OrthoDB51529
GeneTree (enSembl)ENSG00000141552
Phylogenetic Trees/Animal Genes : TreeFamANAPC11
HOVERGENQ9NYG5
HOGENOMQ9NYG5
Homologs : HomoloGeneANAPC11
Homology/Alignments : Family Browser (UCSC)ANAPC11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANAPC11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANAPC11
dbVarANAPC11
ClinVarANAPC11
1000_GenomesANAPC11 
Exome Variant ServerANAPC11
ExAC (Exome Aggregation Consortium)ANAPC11 (select the gene name)
Genetic variants : HAPMAP51529
Genomic Variants (DGV)ANAPC11 [DGVbeta]
DECIPHER (Syndromes)17:79849589-79858409  ENSG00000141552
CONAN: Copy Number AnalysisANAPC11 
Mutations
ICGC Data PortalANAPC11 
TCGA Data PortalANAPC11 
Broad Tumor PortalANAPC11
OASIS PortalANAPC11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANAPC11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANAPC11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANAPC11
DgiDB (Drug Gene Interaction Database)ANAPC11
DoCM (Curated mutations)ANAPC11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANAPC11 (select a term)
intoGenANAPC11
Cancer3DANAPC11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614534   
Orphanet
MedgenANAPC11
Genetic Testing Registry ANAPC11
NextProtQ9NYG5 [Medical]
TSGene51529
GENETestsANAPC11
Huge Navigator ANAPC11 [HugePedia]
snp3D : Map Gene to Disease51529
BioCentury BCIQANAPC11
ClinGenANAPC11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51529
Chemical/Pharm GKB GenePA24787
Clinical trialANAPC11
Miscellaneous
canSAR (ICR)ANAPC11 (select the gene name)
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANAPC11
EVEXANAPC11
GoPubMedANAPC11
iHOPANAPC11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:14 CET 2017

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