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ANAPC16 (anaphase promoting complex subunit 16)

Identity

Alias (NCBI)APC16
C10orf104
CENP-27
MSAG
bA570G20.3
HGNC (Hugo) ANAPC16
HGNC Alias symbbA570G20.3
FLJ33728
APC16
CENP-27
HGNC Alias namecentromere protein 27
HGNC Previous nameC10orf104
HGNC Previous namechromosome 10 open reading frame 104
LocusID (NCBI) 119504
Atlas_Id 60290
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 72216012 and ends at 72235860 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACSF2 (17q21.33) / ANAPC16 (10q22.1)ANAPC16 (10q22.1) / ANAPC16 (10q22.1)ANAPC16 (10q22.1) / FLNB (3p14.3)
ANAPC16 (10q22.1) / MICU1 (10q22.1)ANAPC16 (10q22.1) / NR4A1 (12q13.13)TRBV20-1 () / ANAPC16 (10q22.1)
ZNF445 (3p21.31) / ANAPC16 (10q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ANAPC16   26976
Cards
Entrez_Gene (NCBI)ANAPC16    anaphase promoting complex subunit 16
AliasesAPC16; C10orf104; CENP-27; MSAG; 
bA570G20.3
GeneCards (Weizmann)ANAPC16
Ensembl hg19 (Hinxton)ENSG00000166295 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166295 [Gene_View]  ENSG00000166295 [Sequence]  chr10:72216012-72235860 [Contig_View]  ANAPC16 [Vega]
ICGC DataPortalENSG00000166295
TCGA cBioPortalANAPC16
AceView (NCBI)ANAPC16
Genatlas (Paris)ANAPC16
SOURCE (Princeton)ANAPC16
Genetics Home Reference (NIH)ANAPC16
Genomic and cartography
GoldenPath hg38 (UCSC)ANAPC16  -     chr10:72216012-72235860 +  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANAPC16  -     10q22.1   [Description]    (hg19-Feb_2009)
GoldenPathANAPC16 - 10q22.1 [CytoView hg19]  ANAPC16 - 10q22.1 [CytoView hg38]
ImmunoBaseENSG00000166295
Genome Data Viewer NCBIANAPC16 [Mapview hg19]  
OMIM613427   
Gene and transcription
Genbank (Entrez)AI038150 AK023981 BC009530 BF975718 BM768948
RefSeq transcript (Entrez)NM_001242546 NM_001242547 NM_001242548 NM_001366791 NM_173473
Consensus coding sequences : CCDS (NCBI)ANAPC16
Gene ExpressionANAPC16 [ NCBI-GEO ]   ANAPC16 [ EBI - ARRAY_EXPRESS ]   ANAPC16 [ SEEK ]   ANAPC16 [ MEM ]
Gene Expression Viewer (FireBrowse)ANAPC16 [ Firebrowse - Broad ]
GenevisibleExpression of ANAPC16 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)119504
GTEX Portal (Tissue expression)ANAPC16
Human Protein AtlasENSG00000166295-ANAPC16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DE5
PhosPhoSitePlusQ96DE5
Domains : Interpro (EBI)APC16   
Domain families : Pfam (Sanger)ANAPC16 (PF17256)   
Domain families : Pfam (NCBI)pfam17256   
Conserved Domain (NCBI)ANAPC16
PDB (RSDB)4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB Europe4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB (PDBSum)4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB (IMB)4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
Structural Biology KnowledgeBase4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
SCOP (Structural Classification of Proteins)4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
CATH (Classification of proteins structures)4RG6    4RG9    4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
SuperfamilyQ96DE5
AlphaFold pdb e-kbQ96DE5   
Human Protein Atlas [tissue]ENSG00000166295-ANAPC16 [tissue]
HPRD12554
Protein Interaction databases
DIP (DOE-UCLA)Q96DE5
IntAct (EBI)Q96DE5
BioGRIDANAPC16
STRING (EMBL)ANAPC16
ZODIACANAPC16
Ontologies - Pathways
QuickGOQ96DE5
Ontology : AmiGOkinetochore  kinetochore  protein binding  nucleoplasm  anaphase-promoting complex  anaphase-promoting complex  cytosol  cytosol  cytosol  ubiquitin-dependent protein catabolic process  cell cycle  regulation of exit from mitosis  protein ubiquitination  protein ubiquitination  protein ubiquitination  anaphase-promoting complex-dependent catabolic process  cell division  regulation of mitotic cell cycle phase transition  
Ontology : EGO-EBIkinetochore  kinetochore  protein binding  nucleoplasm  anaphase-promoting complex  anaphase-promoting complex  cytosol  cytosol  cytosol  ubiquitin-dependent protein catabolic process  cell cycle  regulation of exit from mitosis  protein ubiquitination  protein ubiquitination  protein ubiquitination  anaphase-promoting complex-dependent catabolic process  cell division  regulation of mitotic cell cycle phase transition  
NDEx NetworkANAPC16
Atlas of Cancer Signalling NetworkANAPC16
Wikipedia pathwaysANAPC16
Orthology - Evolution
OrthoDB119504
GeneTree (enSembl)ENSG00000166295
Phylogenetic Trees/Animal Genes : TreeFamANAPC16
Homologs : HomoloGeneANAPC16
Homology/Alignments : Family Browser (UCSC)ANAPC16
Gene fusions - Rearrangements
Fusion : QuiverANAPC16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANAPC16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANAPC16
dbVarANAPC16
ClinVarANAPC16
MonarchANAPC16
1000_GenomesANAPC16 
Exome Variant ServerANAPC16
GNOMAD BrowserENSG00000166295
Varsome BrowserANAPC16
ACMGANAPC16 variants
VarityQ96DE5
Genomic Variants (DGV)ANAPC16 [DGVbeta]
DECIPHERANAPC16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANAPC16 
Mutations
ICGC Data PortalANAPC16 
TCGA Data PortalANAPC16 
Broad Tumor PortalANAPC16
OASIS PortalANAPC16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANAPC16  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANAPC16
Mutations and Diseases : HGMDANAPC16
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANAPC16
DgiDB (Drug Gene Interaction Database)ANAPC16
DoCM (Curated mutations)ANAPC16
CIViC (Clinical Interpretations of Variants in Cancer)ANAPC16
Cancer3DANAPC16
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613427   
Orphanet
DisGeNETANAPC16
MedgenANAPC16
Genetic Testing Registry ANAPC16
NextProtQ96DE5 [Medical]
GENETestsANAPC16
Target ValidationANAPC16
Huge Navigator ANAPC16 [HugePedia]
ClinGenANAPC16
Clinical trials, drugs, therapy
MyCancerGenomeANAPC16
Protein Interactions : CTDANAPC16
Pharm GKB GenePA165548225
PharosQ96DE5
Clinical trialANAPC16
Miscellaneous
canSAR (ICR)ANAPC16
HarmonizomeANAPC16
DataMed IndexANAPC16
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANAPC16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:41:58 CEST 2021

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