Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ANAPC5 (anaphase promoting complex subunit 5)

Identity

Alias (NCBI)APC5
HGNC (Hugo) ANAPC5
HGNC Alias symbAPC5
LocusID (NCBI) 51433
Atlas_Id 47449
Location 12q24.31  [Link to chromosome band 12q24]
Location_base_pair Starts at 121308245 and ends at 121352411 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANAPC5 (12q24.31) / ACYP2 (2p16.2)ANAPC5 (12q24.31) / ANAPC5 (12q24.31)ANAPC5 (12q24.31) / G6PD (Xq28)
ANAPC5 (12q24.31) / KDM2B (12q24.31)ANAPC5 12q24.31 / KDM2B 12q24.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ANAPC5   15713
Cards
Entrez_Gene (NCBI)ANAPC5    anaphase promoting complex subunit 5
AliasesAPC5
GeneCards (Weizmann)ANAPC5
Ensembl hg19 (Hinxton)ENSG00000089053 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000089053 [Gene_View]  ENSG00000089053 [Sequence]  chr12:121308245-121352411 [Contig_View]  ANAPC5 [Vega]
ICGC DataPortalENSG00000089053
TCGA cBioPortalANAPC5
AceView (NCBI)ANAPC5
Genatlas (Paris)ANAPC5
SOURCE (Princeton)ANAPC5
Genetics Home Reference (NIH)ANAPC5
Genomic and cartography
GoldenPath hg38 (UCSC)ANAPC5  -     chr12:121308245-121352411 -  12q24.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANAPC5  -     12q24.31   [Description]    (hg19-Feb_2009)
GoldenPathANAPC5 - 12q24.31 [CytoView hg19]  ANAPC5 - 12q24.31 [CytoView hg38]
ImmunoBaseENSG00000089053
genome Data Viewer NCBIANAPC5 [Mapview hg19]  
OMIM606948   
Gene and transcription
Genbank (Entrez)AA349724 AF191339 AI879332 AK025614 AK054779
RefSeq transcript (Entrez)NM_001137559 NM_001330489 NM_016237
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ANAPC5
Alternative Splicing GalleryENSG00000089053
Gene ExpressionANAPC5 [ NCBI-GEO ]   ANAPC5 [ EBI - ARRAY_EXPRESS ]   ANAPC5 [ SEEK ]   ANAPC5 [ MEM ]
Gene Expression Viewer (FireBrowse)ANAPC5 [ Firebrowse - Broad ]
GenevisibleExpression of ANAPC5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51433
GTEX Portal (Tissue expression)ANAPC5
Human Protein AtlasENSG00000089053-ANAPC5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJX4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJX4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJX4
Splice isoforms : SwissVarQ9UJX4
PhosPhoSitePlusQ9UJX4
Domains : Interpro (EBI)Apc5    Apc5_dom    TPR-like_helical_dom_sf    TPR_repeat   
Domain families : Pfam (Sanger)ANAPC5 (PF12862)   
Domain families : Pfam (NCBI)pfam12862   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)ANAPC5
Blocks (Seattle)ANAPC5
PDB (RSDB)4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB Europe4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB (PDBSum)4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
PDB (IMB)4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
Structural Biology KnowledgeBase4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
SCOP (Structural Classification of Proteins)4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
CATH (Classification of proteins structures)4UI9    5A31    5G04    5G05    5KHR    5KHU    5L9T    5L9U    5LCW    6Q6G    6Q6H    6TLJ    6TM5   
SuperfamilyQ9UJX4
Human Protein Atlas [tissue]ENSG00000089053-ANAPC5 [tissue]
Peptide AtlasQ9UJX4
HPRD10453
IPIIPI00008247   IPI00375602   IPI00383638   IPI01011593   IPI00788662   IPI01010709   IPI00798336   IPI01016032   IPI01009549   IPI01014487   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJX4
IntAct (EBI)Q9UJX4
BioGRIDANAPC5
STRING (EMBL)ANAPC5
ZODIACANAPC5
Ontologies - Pathways
QuickGOQ9UJX4
Ontology : AmiGOnucleus  nucleoplasm  anaphase-promoting complex  anaphase-promoting complex  spindle  cytosol  ubiquitin-dependent protein catabolic process  cell cycle  protein phosphatase binding  anaphase-promoting complex-dependent catabolic process  anaphase-promoting complex-dependent catabolic process  positive regulation of mitotic metaphase/anaphase transition  cell division  protein K11-linked ubiquitination  protein K11-linked ubiquitination  regulation of mitotic cell cycle phase transition  
Ontology : EGO-EBInucleus  nucleoplasm  anaphase-promoting complex  anaphase-promoting complex  spindle  cytosol  ubiquitin-dependent protein catabolic process  cell cycle  protein phosphatase binding  anaphase-promoting complex-dependent catabolic process  anaphase-promoting complex-dependent catabolic process  positive regulation of mitotic metaphase/anaphase transition  cell division  protein K11-linked ubiquitination  protein K11-linked ubiquitination  regulation of mitotic cell cycle phase transition  
Pathways : KEGGCell cycle    Oocyte meiosis    Ubiquitin mediated proteolysis    Progesterone-mediated oocyte maturation    HTLV-I infection   
NDEx NetworkANAPC5
Atlas of Cancer Signalling NetworkANAPC5
Wikipedia pathwaysANAPC5
Orthology - Evolution
OrthoDB51433
GeneTree (enSembl)ENSG00000089053
Phylogenetic Trees/Animal Genes : TreeFamANAPC5
HOGENOMQ9UJX4
Homologs : HomoloGeneANAPC5
Homology/Alignments : Family Browser (UCSC)ANAPC5
Gene fusions - Rearrangements
Fusion : MitelmanANAPC5/KDM2B [12q24.31/12q24.31]  
Fusion PortalANAPC5 12q24.31 KDM2B 12q24.31 BRCA
Fusion : QuiverANAPC5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANAPC5 [hg38]
dbVarANAPC5
ClinVarANAPC5
MonarchANAPC5
1000_GenomesANAPC5 
Exome Variant ServerANAPC5
GNOMAD BrowserENSG00000089053
Varsome BrowserANAPC5
Genomic Variants (DGV)ANAPC5 [DGVbeta]
DECIPHERANAPC5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANAPC5 
Mutations
ICGC Data PortalANAPC5 
TCGA Data PortalANAPC5 
Broad Tumor PortalANAPC5
OASIS PortalANAPC5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANAPC5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANAPC5
Mutations and Diseases : HGMDANAPC5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANAPC5
DgiDB (Drug Gene Interaction Database)ANAPC5
DoCM (Curated mutations)ANAPC5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANAPC5 (select a term)
intoGenANAPC5
Cancer3DANAPC5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606948   
Orphanet
DisGeNETANAPC5
MedgenANAPC5
Genetic Testing Registry ANAPC5
NextProtQ9UJX4 [Medical]
GENETestsANAPC5
Target ValidationANAPC5
Huge Navigator ANAPC5 [HugePedia]
ClinGenANAPC5
Clinical trials, drugs, therapy
MyCancerGenomeANAPC5
Protein Interactions : CTD
Pharm GKB GenePA24788
PharosQ9UJX4
Clinical trialANAPC5
Miscellaneous
canSAR (ICR)ANAPC5 (select the gene name)
HarmonizomeANAPC5
DataMed IndexANAPC5
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANAPC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:10:49 CET 2021
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