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ANAPC5 (anaphase promoting complex subunit 5)

Identity

Other namesAPC5
HGNC (Hugo) ANAPC5
LocusID (NCBI) 51433
Location 12q24.31
Location_base_pair Starts at 121746048 and ends at 121792012 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ANAPC5   15713
Entrez_Gene (NCBI)ANAPC5  51433  anaphase promoting complex subunit 5
Cards
GeneCards (Weizmann)ANAPC5
Ensembl (Hinxton)ENSG00000089053 [Gene_View]  chr12:121746048-121792012 [Contig_View]  ANAPC5 [Vega]
AceView (NCBI)ANAPC5
Genatlas (Paris)ANAPC5
SOURCE (Stanford)NM_001137559 NM_016237
Genomic and cartography
GoldenPath (UCSC)ANAPC5  -  12q24.31   chr12:121746048-121792012 -  12q24.31   [Description]    (hg19-Feb_2009)
EnsemblANAPC5 - 12q24.31 [CytoView]
Mapping of homologs : NCBIANAPC5 [Mapview]
OMIM606948   
Gene and transcription
Genbank (Entrez)AA349724 AF191339 AI879332 AK025614 AK054779
RefSeq transcript (SRS)NM_001137559 NM_016237
RefSeq transcript (Entrez)NM_001137559 NM_016237
RefSeq genomic (SRS)AC_000144 NC_000012 NC_018923 NT_009775 NW_001838063 NW_004078075
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_009775 NW_001838063 NW_004078075
Consensus coding sequences : CCDS (NCBI)ANAPC5
Cluster EST : UnigeneHs.7101 [ SRS ] Hs.7101 [ NCBI ]
CGAP (NCI)Hs.7101
Alternative Splicing : Fast-db (Paris)GSHG0007865
Alternative Splicing GalleryENSG00000089053
Gene ExpressionANAPC5 [ NCBI-GEO ]   ANAPC5 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJX4 (SRS) Q9UJX4 (Uniprot)
NextProtQ9UJX4
With graphics : InterProQ9UJX4
Splice isoforms : SwissVarQ9UJX4(Swissvar)
Domaine pattern : Prosite (SRS)TPR (PS50005)    TPR_REGION (PS50293)   
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (SRS)Apc5_TPR    TPR-like_helical   
Domains : Interpro (EBI)Apc5_TPR    TPR-like_helical   
Related proteins : CluSTrQ9UJX4
Domain families : Pfam (SRS)Apc5 (PF12862)   
Domain families : Pfam (Sanger)Apc5 (PF12862)   
Domain families : Pfam (NCBI)pfam12862   
DMDM51433
Blocks (Seattle)Q9UJX4
Human Protein AtlasENSG00000089053
HPRD10453
IPIIPI00008247   IPI00375602   IPI00383638   IPI01011593   IPI00788662   IPI01010709   IPI00798336   IPI01016032   IPI01009549   IPI01014487   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJX4
IntAct (EBI)Q9UJX4
FunCoupENSG00000089053
REACTOMEANAPC5
Protein Interaction Database51433
BioGRIDANAPC5
InParanoidQ9UJX4
Interologous Interaction database Q9UJX4
IntegromeDBANAPC5
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ANAPC5
SNP (GeneSNP Utah)ANAPC5
SNP : HGBaseANAPC5
Genetic variants : HAPMAPANAPC5
Somatic Mutations in Cancer : COSMICANAPC5 
CONAN: Copy Number AnalysisANAPC5 
Mutations and Diseases : HGMDANAPC5
OMIM606948   
GENETests606948   
Disease Genetic AssociationANAPC5
Huge Navigator ANAPC5 [HugePedia]  ANAPC5 [HugeCancerGEM]
Genomic VariantsANAPC5  ANAPC5 [DGVbeta]
snp3D : Map Gene to Disease51433
General knowledge
Homologs : HomoloGeneANAPC5
Homology/Alignments : Family Browser (UCSC)ANAPC5
Phylogenetic Trees/Animal Genes : TreeFamANAPC5
Chemical/Protein Interactions : CTD51433
Chemical/Pharm GKB GenePA24788
Clinical trialANAPC5
Cancer Resource (Charite)ENSG00000089053
Ontology : AmiGOcell cycle checkpoint  G2/M transition of mitotic cell cycle  mitotic anaphase  mitotic cell cycle  ubiquitin-protein ligase activity  nucleus  nucleoplasm  anaphase-promoting complex  cytosol  ubiquitin-dependent protein catabolic process  mitotic cell cycle spindle assembly checkpoint  protein phosphatase binding  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Ontology : EGO-EBIcell cycle checkpoint  G2/M transition of mitotic cell cycle  mitotic anaphase  mitotic cell cycle  ubiquitin-protein ligase activity  nucleus  nucleoplasm  anaphase-promoting complex  cytosol  ubiquitin-dependent protein catabolic process  mitotic cell cycle spindle assembly checkpoint  protein phosphatase binding  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Pathways : KEGGCell cycleUbiquitin mediated proteolysis
Other databases
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
PubGeneANAPC5
iHOPANAPC5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:19:35 CEST 2013
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