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ANAPC7 (anaphase promoting complex subunit 7)

Identity

Alias_symbol (synonym)APC7
Other alias
HGNC (Hugo) ANAPC7
LocusID (NCBI) 51434
Atlas_Id 45546
Location 12q24.11  [Link to chromosome band 12q24]
Location_base_pair Starts at 110813272 and ends at 110841535 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANAPC7 (12q24.11) / PAH (12q23.2)SEMA3C (7q21.11) / ANAPC7 (12q24.11)SLC2A13 (12q12) / ANAPC7 (12q24.11)
SLC41A2 (12q23.3) / ANAPC7 (12q24.11)ANAPC7 12q24.11 / PAH 12q23.2SLC41A2 12q23.3 / ANAPC7 12q24.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANAPC7   17380
Cards
Entrez_Gene (NCBI)ANAPC7  51434  anaphase promoting complex subunit 7
AliasesAPC7
GeneCards (Weizmann)ANAPC7
Ensembl hg19 (Hinxton)ENSG00000196510 [Gene_View]  chr12:110813272-110841535 [Contig_View]  ANAPC7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000196510 [Gene_View]  chr12:110813272-110841535 [Contig_View]  ANAPC7 [Vega]
ICGC DataPortalENSG00000196510
TCGA cBioPortalANAPC7
AceView (NCBI)ANAPC7
Genatlas (Paris)ANAPC7
WikiGenes51434
SOURCE (Princeton)ANAPC7
Genetics Home Reference (NIH)ANAPC7
Genomic and cartography
GoldenPath hg19 (UCSC)ANAPC7  -     chr12:110813272-110841535 -  12q24.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANAPC7  -     12q24.11   [Description]    (hg38-Dec_2013)
EnsemblANAPC7 - 12q24.11 [CytoView hg19]  ANAPC7 - 12q24.11 [CytoView hg38]
Mapping of homologs : NCBIANAPC7 [Mapview hg19]  ANAPC7 [Mapview hg38]
OMIM606949   
Gene and transcription
Genbank (Entrez)AF191340 AK021809 AL137586 AL157481 AY007104
RefSeq transcript (Entrez)NM_001137664 NM_016238
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929385
Consensus coding sequences : CCDS (NCBI)ANAPC7
Cluster EST : UnigeneHs.719935 [ NCBI ]
CGAP (NCI)Hs.719935
Alternative Splicing GalleryENSG00000196510
Gene ExpressionANAPC7 [ NCBI-GEO ]   ANAPC7 [ EBI - ARRAY_EXPRESS ]   ANAPC7 [ SEEK ]   ANAPC7 [ MEM ]
Gene Expression Viewer (FireBrowse)ANAPC7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51434
GTEX Portal (Tissue expression)ANAPC7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJX3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJX3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJX3
Splice isoforms : SwissVarQ9UJX3
PhosPhoSitePlusQ9UJX3
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)TPR-contain_dom    TPR-like_helical_dom    TPR_2    TPR_repeat   
Domain families : Pfam (Sanger)TPR_2 (PF07719)   
Domain families : Pfam (NCBI)pfam07719   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)ANAPC7
DMDM Disease mutations51434
Blocks (Seattle)ANAPC7
PDB (SRS)3FFL    4UI9    5A31   
PDB (PDBSum)3FFL    4UI9    5A31   
PDB (IMB)3FFL    4UI9    5A31   
PDB (RSDB)3FFL    4UI9    5A31   
Structural Biology KnowledgeBase3FFL    4UI9    5A31   
SCOP (Structural Classification of Proteins)3FFL    4UI9    5A31   
CATH (Classification of proteins structures)3FFL    4UI9    5A31   
SuperfamilyQ9UJX3
Human Protein AtlasENSG00000196510
Peptide AtlasQ9UJX3
HPRD16233
IPIIPI00008248   IPI00915282   IPI01022592   IPI01022736   IPI01022252   IPI01022361   IPI01021898   IPI01022075   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJX3
IntAct (EBI)Q9UJX3
FunCoupENSG00000196510
BioGRIDANAPC7
STRING (EMBL)ANAPC7
ZODIACANAPC7
Ontologies - Pathways
QuickGOQ9UJX3
Ontology : AmiGOnucleus  nucleoplasm  anaphase-promoting complex  cytosol  mitotic nuclear division  protein phosphatase binding  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Ontology : EGO-EBInucleus  nucleoplasm  anaphase-promoting complex  cytosol  mitotic nuclear division  protein phosphatase binding  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  cell division  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  protein K11-linked ubiquitination  
Pathways : KEGGCell cycle    Oocyte meiosis    Ubiquitin mediated proteolysis    Progesterone-mediated oocyte maturation    HTLV-I infection   
NDEx NetworkANAPC7
Atlas of Cancer Signalling NetworkANAPC7
Wikipedia pathwaysANAPC7
Orthology - Evolution
OrthoDB51434
GeneTree (enSembl)ENSG00000196510
Phylogenetic Trees/Animal Genes : TreeFamANAPC7
HOVERGENQ9UJX3
HOGENOMQ9UJX3
Homologs : HomoloGeneANAPC7
Homology/Alignments : Family Browser (UCSC)ANAPC7
Gene fusions - Rearrangements
Fusion : MitelmanANAPC7/PAH [12q24.11/12q23.2]  
Fusion : MitelmanSLC2A13/ANAPC7 [12q12/12q24.11]  [t(12;12)(q12;q24)]  
Fusion : MitelmanSLC41A2/ANAPC7 [12q23.3/12q24.11]  [t(12;12)(q23;q24)]  
Fusion: TCGAANAPC7 12q24.11 PAH 12q23.2 PRAD
Fusion: TCGASLC41A2 12q23.3 ANAPC7 12q24.11 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANAPC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANAPC7
dbVarANAPC7
ClinVarANAPC7
1000_GenomesANAPC7 
Exome Variant ServerANAPC7
ExAC (Exome Aggregation Consortium)ANAPC7 (select the gene name)
Genetic variants : HAPMAP51434
Genomic Variants (DGV)ANAPC7 [DGVbeta]
DECIPHER (Syndromes)12:110813272-110841535  ENSG00000196510
CONAN: Copy Number AnalysisANAPC7 
Mutations
ICGC Data PortalANAPC7 
TCGA Data PortalANAPC7 
Broad Tumor PortalANAPC7
OASIS PortalANAPC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANAPC7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANAPC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANAPC7
DgiDB (Drug Gene Interaction Database)ANAPC7
DoCM (Curated mutations)ANAPC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANAPC7 (select a term)
intoGenANAPC7
Cancer3DANAPC7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606949   
Orphanet
MedgenANAPC7
Genetic Testing Registry ANAPC7
NextProtQ9UJX3 [Medical]
TSGene51434
GENETestsANAPC7
Huge Navigator ANAPC7 [HugePedia]
snp3D : Map Gene to Disease51434
BioCentury BCIQANAPC7
ClinGenANAPC7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51434
Chemical/Pharm GKB GenePA134901290
Clinical trialANAPC7
Miscellaneous
canSAR (ICR)ANAPC7 (select the gene name)
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANAPC7
EVEXANAPC7
GoPubMedANAPC7
iHOPANAPC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:55:44 CET 2017

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