ANG (angiogenin, ribonuclease, RNase A family, 5)

Identity

Other names	ALS9
	MGC22466
	MGC71966
	RNASE4
	RNASE5
HGNC	ANG
Location	14q11.1-q11.2
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	ANG   483
Entrez_Gene	ANG  283  angiogenin, ribonuclease, RNase A family, 5
	Cards
GeneCards	ANG
Ensembl	ANG [Search_View]   ENSG00000214274 [Gene_View]
Genatlas	ANG
GeneLynx	ANG
eGenome	ANG
euGene	283
	Genomic and cartography
GoldenPath	ANG  -     chr14:20226772-20232185 +  14q11.2   [Description]    (hg18-March_2006)
Ensembl	ANG - 14q11.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	ANG
	Gene and transcription
Genbank	AK313989 [ ENTREZ ]
Genbank	AV646929 [ ENTREZ ]
Genbank	BC020704 [ ENTREZ ]
Genbank	BC054880 [ ENTREZ ]
Genbank	BC062698 [ ENTREZ ]
RefSeq	NM_001097577 [ SRS ]    NM_001097577 [ ENTREZ ]
RefSeq	NM_001145 [ SRS ]    NM_001145 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
AceView	ANG AceView - NCBI
Unigene	Hs.283749 [ SRS ]    Hs.283749 [ NCBI ]     HS283749 [ spliceNest ]
Fast-db	22 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P03950 [ SRS]    P03950 [ EXPASY ]     P03950 [ INTERPRO ]     P03950 [ UNIPROT ]
Prosite	PS00127 RNASE_PANCREATIC [ SRS ]    PS00127 RNASE_PANCREATIC [ Expasy ]
Interpro	IPR001427 RNaseA [ SRS ]    IPR001427 RNaseA [ EBI ]
CluSTr	P03950
Pfam	PF00074 RnaseA [ SRS ]    PF00074 RnaseA [ Sanger ]    pfam00074 [ NCBI-CDD ]
Smart	SM00092 RNAse_Pc [EMBL]
Prodom	PD000535 RNaseA[INRA-Toulouse]
Prodom	P03950 ANGI_HUMAN [ Domain structure ]   P03950 ANGI_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P03950
PDB	1A4Y [ SRS ]    1A4Y [ PdbSum ],   1A4Y [ IMB ]   1A4Y [ RSDB ]
PDB	1ANG [ SRS ]    1ANG [ PdbSum ],   1ANG [ IMB ]   1ANG [ RSDB ]
PDB	1AWZ [ SRS ]    1AWZ [ PdbSum ],   1AWZ [ IMB ]   1AWZ [ RSDB ]
PDB	1B1E [ SRS ]    1B1E [ PdbSum ],   1B1E [ IMB ]   1B1E [ RSDB ]
PDB	1B1I [ SRS ]    1B1I [ PdbSum ],   1B1I [ IMB ]   1B1I [ RSDB ]
PDB	1B1J [ SRS ]    1B1J [ PdbSum ],   1B1J [ IMB ]   1B1J [ RSDB ]
PDB	1GV7 [ SRS ]    1GV7 [ PdbSum ],   1GV7 [ IMB ]   1GV7 [ RSDB ]
PDB	1H0D [ SRS ]    1H0D [ PdbSum ],   1H0D [ IMB ]   1H0D [ RSDB ]
PDB	1H52 [ SRS ]    1H52 [ PdbSum ],   1H52 [ IMB ]   1H52 [ RSDB ]
PDB	1H53 [ SRS ]    1H53 [ PdbSum ],   1H53 [ IMB ]   1H53 [ RSDB ]
PDB	1HBY [ SRS ]    1HBY [ PdbSum ],   1HBY [ IMB ]   1HBY [ RSDB ]
PDB	1K58 [ SRS ]    1K58 [ PdbSum ],   1K58 [ IMB ]   1K58 [ RSDB ]
PDB	1K59 [ SRS ]    1K59 [ PdbSum ],   1K59 [ IMB ]   1K59 [ RSDB ]
PDB	1K5A [ SRS ]    1K5A [ PdbSum ],   1K5A [ IMB ]   1K5A [ RSDB ]
PDB	1K5B [ SRS ]    1K5B [ PdbSum ],   1K5B [ IMB ]   1K5B [ RSDB ]
PDB	1UN3 [ SRS ]    1UN3 [ PdbSum ],   1UN3 [ IMB ]   1UN3 [ RSDB ]
PDB	1UN4 [ SRS ]    1UN4 [ PdbSum ],   1UN4 [ IMB ]   1UN4 [ RSDB ]
PDB	1UN5 [ SRS ]    1UN5 [ PdbSum ],   1UN5 [ IMB ]   1UN5 [ RSDB ]
PDB	2ANG [ SRS ]    2ANG [ PdbSum ],   2ANG [ IMB ]   2ANG [ RSDB ]
HPRD	00105
	Protein Interaction databases
DIP	P03950
IntAct	P03950
	Polymorphism : SNP, mutations, diseases
OMIM	105400;105850;611895    [ map ]
GENECLINICS	105400;105850;611895
SNP	ANG [dbSNP-NCBI]
SNP	NM_001097577 [SNP-NCI]
SNP	NM_001145 [SNP-NCI]
SNP	ANG [GeneSNPs - Utah]  ANG] [HGBASE - SRS]
HAPMAP	ANG [HAPMAP]
HGMD	ANG
	General knowledge
Family Browser	ANG [UCSC Family Browser]
SOURCE	NM_001097577
SOURCE	NM_001145
SMD	Hs.283749
SAGE	Hs.283749
Enzyme	3.1.27.- [ Enzyme-Expasy ]   3.1.27.- [ Enzyme-SRS ]   3.1.27.- [ IntEnz-EBI ]   3.1.27.- [ BRENDA ]   3.1.27.- [ KEGG ]   3.1.27.- [ WIT ]
GO	angiogenesis [Amigo]  angiogenesis
GO	angiogenesis [Amigo]  angiogenesis
GO	ovarian follicle development [Amigo]  ovarian follicle development
GO	oocyte maturation [Amigo]  oocyte maturation
GO	response to hypoxia [Amigo]  response to hypoxia
GO	response to hypoxia [Amigo]  response to hypoxia
GO	placenta development [Amigo]  placenta development
GO	positive regulation of endothelial cell proliferation [Amigo]  positive regulation of endothelial cell proliferation
GO	nucleic acid binding [Amigo]  nucleic acid binding
GO	DNA binding [Amigo]  DNA binding
GO	actin binding [Amigo]  actin binding
GO	endonuclease activity [Amigo]  endonuclease activity
GO	endonuclease activity [Amigo]  endonuclease activity
GO	pancreatic ribonuclease activity [Amigo]  pancreatic ribonuclease activity
GO	ribonuclease activity [Amigo]  ribonuclease activity
GO	receptor binding [Amigo]  receptor binding
GO	copper ion binding [Amigo]  copper ion binding
GO	extracellular region [Amigo]  extracellular region
GO	basal lamina [Amigo]  basal lamina
GO	extracellular space [Amigo]  extracellular space
GO	nucleus [Amigo]  nucleus
GO	nucleolus [Amigo]  nucleolus
GO	diacylglycerol biosynthetic process [Amigo]  diacylglycerol biosynthetic process
GO	cell communication [Amigo]  cell communication
GO	activation of phospholipase C activity [Amigo]  activation of phospholipase C activity
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	heparin binding [Amigo]  heparin binding
GO	rRNA transcription [Amigo]  rRNA transcription
GO	response to hormone stimulus [Amigo]  response to hormone stimulus
GO	cell migration [Amigo]  cell migration
GO	hydrolase activity [Amigo]  hydrolase activity
GO	negative regulation of translation [Amigo]  negative regulation of translation
GO	rRNA binding [Amigo]  rRNA binding
GO	actin filament polymerization [Amigo]  actin filament polymerization
GO	cell differentiation [Amigo]  cell differentiation
GO	growth cone [Amigo]  growth cone
GO	activation of protein kinase B activity [Amigo]  activation of protein kinase B activity
GO	angiogenin-PRI complex [Amigo]  angiogenin-PRI complex
GO	activation of phospholipase A2 [Amigo]  activation of phospholipase A2
GO	peptide binding [Amigo]  peptide binding
GO	positive regulation of phosphorylation [Amigo]  positive regulation of phosphorylation
GO	homeostatic process [Amigo]  homeostatic process
GO	cell soma [Amigo]  cell soma
GO	negative regulation of smooth muscle cell proliferation [Amigo]  negative regulation of smooth muscle cell proliferation
GO	positive regulation of protein secretion [Amigo]  positive regulation of protein secretion
GO	positive regulation of protein secretion [Amigo]  positive regulation of protein secretion
PubGene	ANG
TreeFam	ANG
CTD	283 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	ANG Related clones (RZPD - Berlin)
	PubMed
PubMed	75 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:00:05 2008