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ANGPTL4 (angiopoietin like 4)

Identity

Alias_namesangiopoietin-like 4
Alias_symbol (synonym)pp1158
PGAR
ARP4
HFARP
FIAF
NL2
Other aliasHARP
TGQTL
UNQ171
HGNC (Hugo) ANGPTL4
LocusID (NCBI) 51129
Atlas_Id 43819
Location 19p13.2  [Link to chromosome band 19p13]
Location_base_pair Starts at 8364127 and ends at 8374375 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANGPTL4 (19p13.2) / PAX8 (2q13)ANGPTL4 (19p13.2) / RPL28 (19q13.42)PAX8 (2q13) / ANGPTL4 (19p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANGPTL4   16039
Cards
Entrez_Gene (NCBI)ANGPTL4  51129  angiopoietin like 4
AliasesARP4; FIAF; HARP; HFARP; 
NL2; PGAR; TGQTL; UNQ171; pp1158
GeneCards (Weizmann)ANGPTL4
Ensembl hg19 (Hinxton)ENSG00000167772 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167772 [Gene_View]  chr19:8364127-8374375 [Contig_View]  ANGPTL4 [Vega]
ICGC DataPortalENSG00000167772
TCGA cBioPortalANGPTL4
AceView (NCBI)ANGPTL4
Genatlas (Paris)ANGPTL4
WikiGenes51129
SOURCE (Princeton)ANGPTL4
Genetics Home Reference (NIH)ANGPTL4
Genomic and cartography
GoldenPath hg38 (UCSC)ANGPTL4  -     chr19:8364127-8374375 +  19p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANGPTL4  -     19p13.2   [Description]    (hg19-Feb_2009)
EnsemblANGPTL4 - 19p13.2 [CytoView hg19]  ANGPTL4 - 19p13.2 [CytoView hg38]
Mapping of homologs : NCBIANGPTL4 [Mapview hg19]  ANGPTL4 [Mapview hg38]
OMIM605910   615881   
Gene and transcription
Genbank (Entrez)AB056477 AF153606 AF169312 AF202636 AK222489
RefSeq transcript (Entrez)NM_001039667 NM_016109 NM_139314
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ANGPTL4
Cluster EST : UnigeneHs.9613 [ NCBI ]
CGAP (NCI)Hs.9613
Alternative Splicing GalleryENSG00000167772
Gene ExpressionANGPTL4 [ NCBI-GEO ]   ANGPTL4 [ EBI - ARRAY_EXPRESS ]   ANGPTL4 [ SEEK ]   ANGPTL4 [ MEM ]
Gene Expression Viewer (FireBrowse)ANGPTL4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51129
GTEX Portal (Tissue expression)ANGPTL4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BY76   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BY76  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BY76
Splice isoforms : SwissVarQ9BY76
PhosPhoSitePlusQ9BY76
Domaine pattern : Prosite (Expaxy)FIBRINOGEN_C_1 (PS00514)    FIBRINOGEN_C_2 (PS51406)   
Domains : Interpro (EBI)ANGPTL4    Fibrinogen_a/b/g_C_1    Fibrinogen_a/b/g_C_2    Fibrinogen_a/b/g_C_dom    Fibrinogen_CS   
Domain families : Pfam (Sanger)Fibrinogen_C (PF00147)   
Domain families : Pfam (NCBI)pfam00147   
Domain families : Smart (EMBL)FBG (SM00186)  
Conserved Domain (NCBI)ANGPTL4
DMDM Disease mutations51129
Blocks (Seattle)ANGPTL4
SuperfamilyQ9BY76
Human Protein AtlasENSG00000167772
Peptide AtlasQ9BY76
HPRD16173
IPIIPI00153060   IPI01010425   IPI00740170   
Protein Interaction databases
DIP (DOE-UCLA)Q9BY76
IntAct (EBI)Q9BY76
FunCoupENSG00000167772
BioGRIDANGPTL4
STRING (EMBL)ANGPTL4
ZODIACANGPTL4
Ontologies - Pathways
QuickGOQ9BY76
Ontology : AmiGOangiogenesis  response to hypoxia  enzyme inhibitor activity  protein binding  extracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  cell differentiation  identical protein binding  negative regulation of apoptotic process  positive regulation of angiogenesis  negative regulation of lipoprotein lipase activity  protein homooligomerization  triglyceride homeostasis  blood microparticle  negative regulation of endothelial cell apoptotic process  
Ontology : EGO-EBIangiogenesis  response to hypoxia  enzyme inhibitor activity  protein binding  extracellular region  extracellular region  proteinaceous extracellular matrix  extracellular space  cell differentiation  identical protein binding  negative regulation of apoptotic process  positive regulation of angiogenesis  negative regulation of lipoprotein lipase activity  protein homooligomerization  triglyceride homeostasis  blood microparticle  negative regulation of endothelial cell apoptotic process  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkANGPTL4
Atlas of Cancer Signalling NetworkANGPTL4
Wikipedia pathwaysANGPTL4
Orthology - Evolution
OrthoDB51129
GeneTree (enSembl)ENSG00000167772
Phylogenetic Trees/Animal Genes : TreeFamANGPTL4
HOVERGENQ9BY76
HOGENOMQ9BY76
Homologs : HomoloGeneANGPTL4
Homology/Alignments : Family Browser (UCSC)ANGPTL4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANGPTL4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANGPTL4
dbVarANGPTL4
ClinVarANGPTL4
1000_GenomesANGPTL4 
Exome Variant ServerANGPTL4
ExAC (Exome Aggregation Consortium)ANGPTL4 (select the gene name)
Genetic variants : HAPMAP51129
Genomic Variants (DGV)ANGPTL4 [DGVbeta]
DECIPHERANGPTL4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANGPTL4 
Mutations
ICGC Data PortalANGPTL4 
TCGA Data PortalANGPTL4 
Broad Tumor PortalANGPTL4
OASIS PortalANGPTL4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANGPTL4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANGPTL4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANGPTL4
DgiDB (Drug Gene Interaction Database)ANGPTL4
DoCM (Curated mutations)ANGPTL4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANGPTL4 (select a term)
intoGenANGPTL4
Cancer3DANGPTL4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605910    615881   
Orphanet
MedgenANGPTL4
Genetic Testing Registry ANGPTL4
NextProtQ9BY76 [Medical]
TSGene51129
GENETestsANGPTL4
Target ValidationANGPTL4
Huge Navigator ANGPTL4 [HugePedia]
snp3D : Map Gene to Disease51129
BioCentury BCIQANGPTL4
ClinGenANGPTL4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51129
Chemical/Pharm GKB GenePA24797
Clinical trialANGPTL4
Miscellaneous
canSAR (ICR)ANGPTL4 (select the gene name)
Probes
Litterature
PubMed152 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANGPTL4
EVEXANGPTL4
GoPubMedANGPTL4
iHOPANGPTL4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 18:57:11 CEST 2017

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