ANGPTL8 (angiopoietin like 8)

2016-10-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
C19orf80,PRO1185,PVPA599,RIFL,TD26

Other Information

Locus ID:

NCBI: 55908
MIM: 616223
HGNC: 24933
Ensembl: ENSG00000130173

Variants:

dbSNP: 55908
ClinVar: 55908
TCGA: ENSG00000130173
COSMIC: ANGPTL8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130173ENST00000252453Q6UXH0
ENSG00000130173ENST00000587543K7EJY6
ENSG00000130173ENST00000591200K7EIY2
ENSG00000130173ENST00000616433Q6UXH0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
Chylomicron-mediated lipid transportREACTOMER-HSA-174800

References

Pubmed IDYearTitleCitations
228095132012Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels.117
225690732012Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism.101
248526942014Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity.73
248526942014Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity.73
250243952014Increased circulating levels of betatrophin in newly diagnosed type 2 diabetic patients.65
240780582014Increased circulating levels of betatrophin in individuals with long-standing type 1 diabetes.59
250509012014Circulating betatrophin concentrations are decreased in human obesity and type 2 diabetes.57
270536792016The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking.49
234158642013Emerging roles of Lipasin as a critical lipid regulator.48
232614422013Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family.47

Citation

Dessen P

ANGPTL8 (angiopoietin like 8)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56550/angptl8