ANK1 (ankyrin 1, erythrocytic)

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

ANK1 (ankyrin 1, erythrocytic)

Identity

Other names	ANK
	SPH1
	SPH2
HGNC (Hugo)	ANK1
LocusID (NCBI)	286
Location	8p11.21
Location_base_pair	Starts at 41510744 and ends at 41655140 bp from pter ( according to hg19-Feb_2009)
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to How to contribute

DNA/RNA

External links

	Nomenclature
HGNC (Hugo)	ANK1 492
	Cards
Entrez_Gene (NCBI)	ANK1 286 ankyrin 1, erythrocytic
GeneCards (Weizmann)	ANK1
Ensembl hg19 (Hinxton)	ENSG00000029534 [Gene_View] chr8:41510744-41655140 [Contig_View] ANK1 [Vega]
Ensembl hg38 (Hinxton)	ENSG00000029534 [Gene_View] chr8:41510744-41655140 [Contig_View] ANK1 [Vega]
ICGC DataPortal	ENSG00000029534
cBioPortal	ANK1
AceView (NCBI)	ANK1
Genatlas (Paris)	ANK1
WikiGenes	286
SOURCE (Princeton)	ANK1
	Genomic and cartography
GoldenPath hg19 (UCSC)	ANK1 - chr8:41510744-41655140 - 8p11.21 [Description] (hg19-Feb_2009)
GoldenPath hg38 (UCSC)	ANK1 - 8p11.21 [Description] (hg38-Dec_2013)
Ensembl	ANK1 - 8p11.21 [CytoView hg19] ANK1 - 8p11.21 [CytoView hg38]
Mapping of homologs : NCBI	ANK1 [Mapview hg19] ANK1 [Mapview hg38]
OMIM	182900 612641
	Gene and transcription
Genbank (Entrez)	AA404587 AB209418 AI167814 AI684839 AK126647
RefSeq transcript (Entrez)	NM_000037 NM_001142445 NM_001142446 NM_020475 NM_020476 NM_020477 NM_020478 NM_020479 NM_020480 NM_020481
RefSeq genomic (Entrez)	AC_000140 NC_000008 NC_018919 NG_012820 NT_167187 NW_001839130 NW_004929337
Consensus coding sequences : CCDS (NCBI)	ANK1
Cluster EST : Unigene	Hs.708861 [ NCBI ]
CGAP (NCI)	Hs.708861
Alternative Splicing : Fast-db (Paris)	GSHG0029546
Alternative Splicing Gallery	ENSG00000029534
Gene Expression	ANK1 [ NCBI-GEO ] ANK1 [ SEEK ] ANK1 [ MEM ]
SOURCE (Princeton)	Expression in : [Normal Tissue Atlas] [carcinoma Classsification] [NCI60]
	Protein : pattern, domain, 3D structure
UniProt/SwissProt	P16157 (Uniprot)
NextProt	P16157 [Medical]
With graphics : InterPro	P16157
Splice isoforms : SwissVar	P16157 (Swissvar)
Domaine pattern : Prosite (Expaxy)	ANK_REP_REGION (PS50297) ANK_REPEAT (PS50088) DEATH_DOMAIN (PS50017) ZU5 (PS51145)
Domains : Interpro (EBI)	Ankyrin_rpt Ankyrin_rpt-contain_dom DEATH-like_dom Death_domain ZU5
Related proteins : CluSTr	P16157
Domain families : Pfam (Sanger)	Ank (PF00023) Death (PF00531) ZU5 (PF00791)
Domain families : Pfam (NCBI)	pfam00023 pfam00531 pfam00791
Domain families : Smart (EMBL)	ANK (SM00248) DEATH (SM00005) ZU5 (SM00218)
DMDM Disease mutations	286
Blocks (Seattle)	P16157
PDB (SRS)	1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
PDB (PDBSum)	1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
PDB (IMB)	1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
PDB (RSDB)	1N11 2YQF 2YVI 3F59 3KBT 3KBU 3UD1 3UD2
Human Protein Atlas	ENSG00000029534
Peptide Atlas	P16157
HPRD	01693
IPI	IPI00216697 IPI00744986 IPI00744846 IPI00747536 IPI00749301 IPI00748895 IPI00748439 IPI00748074 IPI00748154 IPI00007623 IPI00743884 IPI00646300 IPI00007625 IPI00748330 IPI00654646 IPI00297532 IPI00374973 IPI00745348 IPI00744895 IPI00744408 IPI00747552 IPI00984523 IPI00917882 IPI00182779 IPI00878241 IPI00449128 IPI00795357 IPI00980703
	Protein Interaction databases
DIP (DOE-UCLA)	P16157
IntAct (EBI)	P16157
FunCoup	ENSG00000029534
BioGRID	ANK1
IntegromeDB	ANK1
STRING (EMBL)	ANK1
	Ontologies - Pathways
QuickGO	P16157
Ontology : AmiGO	structural molecule activity structural constituent of cytoskeleton protein binding nucleus cytosol cytoskeleton plasma membrane plasma membrane porphyrin-containing compound biosynthetic process exocytosis ER to Golgi vesicle-mediated transport cytoskeleton organization signal transduction axon guidance cytoskeletal adaptor activity cytoskeletal adaptor activity positive regulation of organelle organization spectrin-associated cytoskeleton monovalent inorganic cation transport basolateral plasma membrane sarcoplasmic reticulum enzyme binding enzyme binding Z disc spectrin binding spectrin binding spectrin binding axolemma cortical cytoskeleton M band sarcolemma maintenance of epithelial cell apical/basal polarity postsynaptic membrane erythrocyte development ATPase binding protein targeting to plasma membrane
Ontology : EGO-EBI	structural molecule activity structural constituent of cytoskeleton protein binding nucleus cytosol cytoskeleton plasma membrane plasma membrane porphyrin-containing compound biosynthetic process exocytosis ER to Golgi vesicle-mediated transport cytoskeleton organization signal transduction axon guidance cytoskeletal adaptor activity cytoskeletal adaptor activity positive regulation of organelle organization spectrin-associated cytoskeleton monovalent inorganic cation transport basolateral plasma membrane sarcoplasmic reticulum enzyme binding enzyme binding Z disc spectrin binding spectrin binding spectrin binding axolemma cortical cytoskeleton M band sarcolemma maintenance of epithelial cell apical/basal polarity postsynaptic membrane erythrocyte development ATPase binding protein targeting to plasma membrane
Pathways : BIOCARTA	Synaptic Proteins at the Synaptic Junction [Genes]
Pathways : KEGG	Proteoglycans in cancer
Protein Interaction Database	ANK1
DoCM (Curated mutations)	ANK1
Wikipedia pathways	ANK1
	Gene fusion - rearrangements
	Polymorphisms : SNP, variants
NCBI Variation Viewer	ANK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)	ANK1
dbVar	ANK1
ClinVar	ANK1
1000_Genomes	ANK1
Exome Variant Server	ANK1
SNP (GeneSNP Utah)	ANK1
SNP : HGBase	ANK1
Genetic variants : HAPMAP	ANK1
Genomic Variants (DGV)	ANK1 [DGVbeta]
	Mutations
ICGC Data Portal	ENSG00000029534
Somatic Mutations in Cancer : COSMIC	ANK1
CONAN: Copy Number Analysis	ANK1
LOVD (Leiden Open Variation Database)	Whole genome datasets
LOVD (Leiden Open Variation Database)	LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)	LOVD 3.0 shared installation
Impact of mutations	[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor]
	Diseases
DECIPHER (Syndromes)	8:41510744-41655140
Mutations and Diseases : HGMD	ANK1
OMIM	182900 612641
Medgen	ANK1
NextProt	P16157 [Medical]
GENETests	ANK1
Disease Genetic Association	ANK1
Huge Navigator	ANK1 [HugePedia] ANK1 [HugeCancerGEM]
snp3D : Map Gene to Disease	286
DGIdb (Drug Gene Interaction db)	ANK1
	General knowledge
Homologs : HomoloGene	ANK1
Homology/Alignments : Family Browser (UCSC)	ANK1
Phylogenetic Trees/Animal Genes : TreeFam	ANK1
Chemical/Protein Interactions : CTD	286
Chemical/Pharm GKB Gene	PA24798
Clinical trial	ANK1
Cancer Resource (Charite)	ENSG00000029534
	Other databases
	Probes
	Litterature
PubMed	71 Pubmed reference(s) in Entrez
CoreMine	ANK1
GoPubMed	ANK1
iHOP	ANK1

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

Updated	12-2014	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Feb 14 14:38:01 CET 2015

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For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.