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ANKRD11 (ankyrin repeat domain 11)

Identity

Alias (NCBI)ANCO-1
ANCO1
LZ16
T13
HGNC (Hugo) ANKRD11
HGNC Alias symbLZ16
T13
LocusID (NCBI) 29123
Atlas_Id 644
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89267632 and ends at 89490561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAM10 (15q21.3) / ANKRD11 (16q24.3)ANKRD11 (16q24.3) / ANKRD11 (16q24.3)ANKRD11 (16q24.3) / DPEP1 (16q24.3)
ANKRD11 (16q24.3) / FANCA (16q24.3)ANKRD11 (16q24.3) / FAU (11q13.1)ANKRD11 (16q24.3) / GOLGB1 (3q13.33)
ANKRD11 (16q24.3) / HABP4 (9q22.32)ANKRD11 (16q24.3) / HUWE1 (Xp11.22)ANKRD11 (16q24.3) / KLHL32 (6q16.1)
ANKRD11 (16q24.3) / LINGO1 (15q24.3)ANKRD11 (16q24.3) / RNF11 (1p32.3)ANKRD11 (16q24.3) / RNF135 (17q11.2)
ANKRD11 (16q24.3) / S100A9 (1q21.3)ANKRD11 (16q24.3) / TGIF1 (18p11.31)CDS2 (20p12.3) / ANKRD11 (16q24.3)
COPG1 (3q21.3) / ANKRD11 (16q24.3)DNAJA2 (16q11.2) / ANKRD11 (16q24.3)FURIN (15q26.1) / ANKRD11 (16q24.3)
IL12RB2 (1p31.3) / ANKRD11 (16q24.3)LDLR (19p13.2) / ANKRD11 (16q24.3)PTK2 (8q24.3) / ANKRD11 (16q24.3)
TYSND1 (10q22.1) / ANKRD11 (16q24.3)ANKRD11 16q24.3 / DPEP1 16q24.3ANKRD11 16q24.3 / FANCA 16q24.3
ANKRD11 16q24.3 / KLHL32 6q16.1ANKRD11 16q24.3 / LINGO1 15q24.3ANKRD11 16q24.3 / TGIF1 18p11.31
PTK2 8q24.3 / ANKRD11 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(16;16)(q24;q24) ANKRD11/SPG7
t(16;20)(q24;p12) CDS2/ANKRD11

External links

 

Nomenclature
HGNC (Hugo)ANKRD11   21316
Cards
Entrez_Gene (NCBI)ANKRD11    ankyrin repeat domain 11
AliasesANCO-1; ANCO1; LZ16; T13
GeneCards (Weizmann)ANKRD11
Ensembl hg19 (Hinxton)ENSG00000167522 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000167522 [Gene_View]  ENSG00000167522 [Sequence]  chr16:89267632-89490561 [Contig_View]  ANKRD11 [Vega]
ICGC DataPortalENSG00000167522
TCGA cBioPortalANKRD11
AceView (NCBI)ANKRD11
Genatlas (Paris)ANKRD11
SOURCE (Princeton)ANKRD11
Genetics Home Reference (NIH)ANKRD11
Genomic and cartography
GoldenPath hg38 (UCSC)ANKRD11  -     chr16:89267632-89490561 -  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANKRD11  -     16q24.3   [Description]    (hg19-Feb_2009)
GoldenPathANKRD11 - 16q24.3 [CytoView hg19]  ANKRD11 - 16q24.3 [CytoView hg38]
ImmunoBaseENSG00000167522
Genome Data Viewer NCBIANKRD11 [Mapview hg19]  
OMIM148050   611192   
Gene and transcription
Genbank (Entrez)AB209186 AF121775 AF130076 AK025964 AK057803
RefSeq transcript (Entrez)NM_001256182 NM_001256183 NM_013275
Consensus coding sequences : CCDS (NCBI)ANKRD11
Gene ExpressionANKRD11 [ NCBI-GEO ]   ANKRD11 [ EBI - ARRAY_EXPRESS ]   ANKRD11 [ SEEK ]   ANKRD11 [ MEM ]
Gene Expression Viewer (FireBrowse)ANKRD11 [ Firebrowse - Broad ]
GenevisibleExpression of ANKRD11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29123
GTEX Portal (Tissue expression)ANKRD11
Human Protein AtlasENSG00000167522-ANKRD11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UB99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UB99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UB99
PhosPhoSitePlusQ6UB99
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)ANKRD11    Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf   
Domain families : Pfam (Sanger)Ank (PF00023)    Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam00023    pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)ANKRD11
SuperfamilyQ6UB99
AlphaFold pdb e-kbQ6UB99   
Human Protein Atlas [tissue]ENSG00000167522-ANKRD11 [tissue]
HPRD12456
Protein Interaction databases
DIP (DOE-UCLA)Q6UB99
IntAct (EBI)Q6UB99
BioGRIDANKRD11
STRING (EMBL)ANKRD11
ZODIACANKRD11
Ontologies - Pathways
QuickGOQ6UB99
Ontology : AmiGOnucleus  nucleus  nucleoplasm  cytosol  anatomical structure morphogenesis  odontogenesis of dentin-containing tooth  skeletal system morphogenesis  face morphogenesis  
Ontology : EGO-EBInucleus  nucleus  nucleoplasm  cytosol  anatomical structure morphogenesis  odontogenesis of dentin-containing tooth  skeletal system morphogenesis  face morphogenesis  
NDEx NetworkANKRD11
Atlas of Cancer Signalling NetworkANKRD11
Wikipedia pathwaysANKRD11
Orthology - Evolution
OrthoDB29123
GeneTree (enSembl)ENSG00000167522
Phylogenetic Trees/Animal Genes : TreeFamANKRD11
Homologs : HomoloGeneANKRD11
Homology/Alignments : Family Browser (UCSC)ANKRD11
Gene fusions - Rearrangements
Fusion : MitelmanANKRD11/DPEP1 [16q24.3/16q24.3]  
Fusion : MitelmanANKRD11/FANCA [16q24.3/16q24.3]  
Fusion : MitelmanANKRD11/KLHL32 [16q24.3/6q16.1]  
Fusion : MitelmanANKRD11/LINGO1 [16q24.3/15q24.3]  
Fusion : MitelmanANKRD11/TGIF1 [16q24.3/18p11.31]  
Fusion : MitelmanPTK2/ANKRD11 [8q24.3/16q24.3]  
Fusion : QuiverANKRD11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANKRD11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANKRD11
dbVarANKRD11
ClinVarANKRD11
MonarchANKRD11
1000_GenomesANKRD11 
Exome Variant ServerANKRD11
GNOMAD BrowserENSG00000167522
Varsome BrowserANKRD11
ACMGANKRD11 variants
VarityQ6UB99
Genomic Variants (DGV)ANKRD11 [DGVbeta]
DECIPHERANKRD11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANKRD11 
Mutations
ICGC Data PortalANKRD11 
TCGA Data PortalANKRD11 
Broad Tumor PortalANKRD11
OASIS PortalANKRD11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANKRD11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANKRD11
Mutations and Diseases : HGMDANKRD11
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANKRD11
DgiDB (Drug Gene Interaction Database)ANKRD11
DoCM (Curated mutations)ANKRD11
CIViC (Clinical Interpretations of Variants in Cancer)ANKRD11
Cancer3DANKRD11
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM148050    611192   
Orphanet2184    19864   
DisGeNETANKRD11
MedgenANKRD11
Genetic Testing Registry ANKRD11
NextProtQ6UB99 [Medical]
GENETestsANKRD11
Target ValidationANKRD11
Huge Navigator ANKRD11 [HugePedia]
ClinGenANKRD11 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeANKRD11
Protein Interactions : CTDANKRD11
Pharm GKB GenePA134861925
PharosQ6UB99
Clinical trialANKRD11
Miscellaneous
canSAR (ICR)ANKRD11
HarmonizomeANKRD11
DataMed IndexANKRD11
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANKRD11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:23 CEST 2021
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