Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ANKRD2 (ankyrin repeat domain 2)

Identity

Alias_namesankyrin repeat domain 2 (stretch responsive muscle)
Alias_symbol (synonym)ARPP
Other alias
HGNC (Hugo) ANKRD2
LocusID (NCBI) 26287
Atlas_Id 46185
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 97572441 and ends at 97583886 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANKRD2   495
Cards
Entrez_Gene (NCBI)ANKRD2  26287  ankyrin repeat domain 2
AliasesARPP
GeneCards (Weizmann)ANKRD2
Ensembl hg19 (Hinxton)ENSG00000165887 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000165887 [Gene_View]  chr10:97572441-97583886 [Contig_View]  ANKRD2 [Vega]
ICGC DataPortalENSG00000165887
TCGA cBioPortalANKRD2
AceView (NCBI)ANKRD2
Genatlas (Paris)ANKRD2
WikiGenes26287
SOURCE (Princeton)ANKRD2
Genetics Home Reference (NIH)ANKRD2
Genomic and cartography
GoldenPath hg38 (UCSC)ANKRD2  -     chr10:97572441-97583886 +  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANKRD2  -     10q24.2   [Description]    (hg19-Feb_2009)
EnsemblANKRD2 - 10q24.2 [CytoView hg19]  ANKRD2 - 10q24.2 [CytoView hg38]
Mapping of homologs : NCBIANKRD2 [Mapview hg19]  ANKRD2 [Mapview hg38]
OMIM610734   
Gene and transcription
Genbank (Entrez)AB058599 AJ249975 AJ304805 AJ346356 AJ583444
RefSeq transcript (Entrez)NM_001129981 NM_001291218 NM_001291219 NM_001346793 NM_001346797 NM_020349
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ANKRD2
Cluster EST : UnigeneHs.73708 [ NCBI ]
CGAP (NCI)Hs.73708
Alternative Splicing GalleryENSG00000165887
Gene ExpressionANKRD2 [ NCBI-GEO ]   ANKRD2 [ EBI - ARRAY_EXPRESS ]   ANKRD2 [ SEEK ]   ANKRD2 [ MEM ]
Gene Expression Viewer (FireBrowse)ANKRD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26287
GTEX Portal (Tissue expression)ANKRD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZV1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZV1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZV1
Splice isoforms : SwissVarQ9GZV1
PhosPhoSitePlusQ9GZV1
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)ANKRD2
DMDM Disease mutations26287
Blocks (Seattle)ANKRD2
SuperfamilyQ9GZV1
Human Protein AtlasENSG00000165887
Peptide AtlasQ9GZV1
HPRD12460
IPIIPI00418217   IPI00514352   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZV1
IntAct (EBI)Q9GZV1
FunCoupENSG00000165887
BioGRIDANKRD2
STRING (EMBL)ANKRD2
ZODIACANKRD2
Ontologies - Pathways
QuickGOQ9GZV1
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  euchromatin  regulation of cytokine production  chromatin binding  nucleus  cytosol  muscle contraction  muscle organ development  structural constituent of muscle  negative regulation of myotube differentiation  PML body  sarcomere  titin binding  I band  skeletal muscle cell differentiation  intracellular membrane-bounded organelle  protein kinase B binding  regulation of transcription from RNA polymerase II promoter in response to oxidative stress  negative regulation of myoblast differentiation  RNA polymerase II sequence-specific DNA binding transcription factor binding  regulation of intrinsic apoptotic signaling pathway by p53 class mediator  regulation of myoblast proliferation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  euchromatin  regulation of cytokine production  chromatin binding  nucleus  cytosol  muscle contraction  muscle organ development  structural constituent of muscle  negative regulation of myotube differentiation  PML body  sarcomere  titin binding  I band  skeletal muscle cell differentiation  intracellular membrane-bounded organelle  protein kinase B binding  regulation of transcription from RNA polymerase II promoter in response to oxidative stress  negative regulation of myoblast differentiation  RNA polymerase II sequence-specific DNA binding transcription factor binding  regulation of intrinsic apoptotic signaling pathway by p53 class mediator  regulation of myoblast proliferation  
NDEx NetworkANKRD2
Atlas of Cancer Signalling NetworkANKRD2
Wikipedia pathwaysANKRD2
Orthology - Evolution
OrthoDB26287
GeneTree (enSembl)ENSG00000165887
Phylogenetic Trees/Animal Genes : TreeFamANKRD2
HOVERGENQ9GZV1
HOGENOMQ9GZV1
Homologs : HomoloGeneANKRD2
Homology/Alignments : Family Browser (UCSC)ANKRD2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANKRD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANKRD2
dbVarANKRD2
ClinVarANKRD2
1000_GenomesANKRD2 
Exome Variant ServerANKRD2
ExAC (Exome Aggregation Consortium)ANKRD2 (select the gene name)
Genetic variants : HAPMAP26287
Genomic Variants (DGV)ANKRD2 [DGVbeta]
DECIPHERANKRD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANKRD2 
Mutations
ICGC Data PortalANKRD2 
TCGA Data PortalANKRD2 
Broad Tumor PortalANKRD2
OASIS PortalANKRD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANKRD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANKRD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANKRD2
DgiDB (Drug Gene Interaction Database)ANKRD2
DoCM (Curated mutations)ANKRD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANKRD2 (select a term)
intoGenANKRD2
Cancer3DANKRD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610734   
Orphanet
MedgenANKRD2
Genetic Testing Registry ANKRD2
NextProtQ9GZV1 [Medical]
TSGene26287
GENETestsANKRD2
Target ValidationANKRD2
Huge Navigator ANKRD2 [HugePedia]
snp3D : Map Gene to Disease26287
BioCentury BCIQANKRD2
ClinGenANKRD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26287
Chemical/Pharm GKB GenePA24804
Clinical trialANKRD2
Miscellaneous
canSAR (ICR)ANKRD2 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANKRD2
EVEXANKRD2
GoPubMedANKRD2
iHOPANKRD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:23:45 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.