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ANKRD26 (ankyrin repeat domain 26)

Identity

Alias (NCBI)THC2
bA145E8.1
HGNC (Hugo) ANKRD26
HGNC Alias symbKIAA1074
HGNC Previous nameTHC2
HGNC Previous namethrombocytopenia 2 (autosomal dominant)
LocusID (NCBI) 22852
Atlas_Id 55967
Location 10p12.1  [Link to chromosome band 10p12]
Location_base_pair Starts at 27004116 and ends at 27100494 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKRD26 (10p12.1) / ANKRD26 (10p12.1)CALM3 (19q13.32) / ANKRD26 (10p12.1)FAM171A1 (10p13) / ANKRD26 (10p12.1)
ZNHIT6 (1p22.3) / ANKRD26 (10p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Therapy-Related Hematopoietic Neoplasia


External links

 

Nomenclature
HGNC (Hugo)ANKRD26   29186
LRG (Locus Reference Genomic)LRG_605
Cards
Entrez_Gene (NCBI)ANKRD26    ankyrin repeat domain 26
AliasesTHC2; bA145E8.1
GeneCards (Weizmann)ANKRD26
Ensembl hg19 (Hinxton)ENSG00000107890 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107890 [Gene_View]  ENSG00000107890 [Sequence]  chr10:27004116-27100494 [Contig_View]  ANKRD26 [Vega]
ICGC DataPortalENSG00000107890
TCGA cBioPortalANKRD26
AceView (NCBI)ANKRD26
Genatlas (Paris)ANKRD26
SOURCE (Princeton)ANKRD26
Genetics Home Reference (NIH)ANKRD26
Genomic and cartography
GoldenPath hg38 (UCSC)ANKRD26  -     chr10:27004116-27100494 -  10p12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANKRD26  -     10p12.1   [Description]    (hg19-Feb_2009)
GoldenPathANKRD26 - 10p12.1 [CytoView hg19]  ANKRD26 - 10p12.1 [CytoView hg38]
ImmunoBaseENSG00000107890
Genome Data Viewer NCBIANKRD26 [Mapview hg19]  
OMIM188000   610855   
Gene and transcription
Genbank (Entrez)AB028997 AK001137 AK128577 AL137351 AL162063
RefSeq transcript (Entrez)NM_001256053 NM_014915
Consensus coding sequences : CCDS (NCBI)ANKRD26
Gene ExpressionANKRD26 [ NCBI-GEO ]   ANKRD26 [ EBI - ARRAY_EXPRESS ]   ANKRD26 [ SEEK ]   ANKRD26 [ MEM ]
Gene Expression Viewer (FireBrowse)ANKRD26 [ Firebrowse - Broad ]
GenevisibleExpression of ANKRD26 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22852
GTEX Portal (Tissue expression)ANKRD26
Human Protein AtlasENSG00000107890-ANKRD26 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UPS8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UPS8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UPS8
PhosPhoSitePlusQ9UPS8
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf    CC144C-like_CC_dom    DUF3496   
Domain families : Pfam (Sanger)Ank (PF00023)    Ank_2 (PF12796)    CCDC144C (PF14915)    DUF3496 (PF12001)   
Domain families : Pfam (NCBI)pfam00023    pfam12796    pfam14915    pfam12001   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)ANKRD26
SuperfamilyQ9UPS8
AlphaFold pdb e-kbQ9UPS8   
Human Protein Atlas [tissue]ENSG00000107890-ANKRD26 [tissue]
HPRD16491
Protein Interaction databases
DIP (DOE-UCLA)Q9UPS8
IntAct (EBI)Q9UPS8
BioGRIDANKRD26
STRING (EMBL)ANKRD26
ZODIACANKRD26
Ontologies - Pathways
QuickGOQ9UPS8
Ontology : AmiGOprotein binding  centrosome  negative regulation of fat cell differentiation  
Ontology : EGO-EBIprotein binding  centrosome  negative regulation of fat cell differentiation  
NDEx NetworkANKRD26
Atlas of Cancer Signalling NetworkANKRD26
Wikipedia pathwaysANKRD26
Orthology - Evolution
OrthoDB22852
GeneTree (enSembl)ENSG00000107890
Phylogenetic Trees/Animal Genes : TreeFamANKRD26
Homologs : HomoloGeneANKRD26
Homology/Alignments : Family Browser (UCSC)ANKRD26
Gene fusions - Rearrangements
Fusion : QuiverANKRD26
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANKRD26 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANKRD26
dbVarANKRD26
ClinVarANKRD26
MonarchANKRD26
1000_GenomesANKRD26 
Exome Variant ServerANKRD26
GNOMAD BrowserENSG00000107890
Varsome BrowserANKRD26
ACMGANKRD26 variants
VarityQ9UPS8
Genomic Variants (DGV)ANKRD26 [DGVbeta]
DECIPHERANKRD26 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANKRD26 
Mutations
ICGC Data PortalANKRD26 
TCGA Data PortalANKRD26 
Broad Tumor PortalANKRD26
OASIS PortalANKRD26 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANKRD26  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANKRD26
Mutations and Diseases : HGMDANKRD26
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANKRD26
DgiDB (Drug Gene Interaction Database)ANKRD26
DoCM (Curated mutations)ANKRD26
CIViC (Clinical Interpretations of Variants in Cancer)ANKRD26
Cancer3DANKRD26
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM188000    610855   
Orphanet17789   
DisGeNETANKRD26
MedgenANKRD26
Genetic Testing Registry ANKRD26
NextProtQ9UPS8 [Medical]
GENETestsANKRD26
Target ValidationANKRD26
Huge Navigator ANKRD26 [HugePedia]
ClinGenANKRD26
Clinical trials, drugs, therapy
MyCancerGenomeANKRD26
Protein Interactions : CTDANKRD26
Pharm GKB GenePA134926710
PharosQ9UPS8
Clinical trialANKRD26
Miscellaneous
canSAR (ICR)ANKRD26
HarmonizomeANKRD26
DataMed IndexANKRD26
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANKRD26
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 14:59:24 CEST 2021

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