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ANKRD28 (ankyrin repeat domain 28)

Identity

Alias_symbol (synonym)KIAA0379
PITK
PP6-ARS-A
PPP1R65
Other alias
HGNC (Hugo) ANKRD28
LocusID (NCBI) 23243
Atlas_Id 52969
Location 3p25.1  [Link to chromosome band 3p25]
Location_base_pair Starts at 15708744 and ends at 15839691 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANKRD28 (3p25.1) / ANKRD28 (3p25.1)ANKRD28 (3p25.1) / ATXN3 (14q32.12)ANKRD28 (3p25.1) / LMNB1 (5q23.2)
ANKRD28 (3p25.1) / NUP98 (11p15.4)ANKRD28 (3p25.1) / RFTN1 (3p25.1)NSD1 (5q35.2) / ANKRD28 (3p25.1)
PTMA (2q37.1) / ANKRD28 (3p25.1)SMARCB1 (22q11.23) / ANKRD28 (3p25.1)ANKRD28 3p25.1 / RFTN1 3p25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(3;11)(p25;p15) ANKRD28/NUP98


External links

Nomenclature
HGNC (Hugo)ANKRD28   29024
Cards
Entrez_Gene (NCBI)ANKRD28  23243  ankyrin repeat domain 28
AliasesPITK; PPP1R65
GeneCards (Weizmann)ANKRD28
Ensembl hg19 (Hinxton)ENSG00000206560 [Gene_View]  chr3:15708744-15839691 [Contig_View]  ANKRD28 [Vega]
Ensembl hg38 (Hinxton)ENSG00000206560 [Gene_View]  chr3:15708744-15839691 [Contig_View]  ANKRD28 [Vega]
ICGC DataPortalENSG00000206560
TCGA cBioPortalANKRD28
AceView (NCBI)ANKRD28
Genatlas (Paris)ANKRD28
WikiGenes23243
SOURCE (Princeton)ANKRD28
Genetics Home Reference (NIH)ANKRD28
Genomic and cartography
GoldenPath hg19 (UCSC)ANKRD28  -     chr3:15708744-15839691 -  3p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANKRD28  -     3p25.1   [Description]    (hg38-Dec_2013)
EnsemblANKRD28 - 3p25.1 [CytoView hg19]  ANKRD28 - 3p25.1 [CytoView hg38]
Mapping of homologs : NCBIANKRD28 [Mapview hg19]  ANKRD28 [Mapview hg38]
OMIM611122   
Gene and transcription
Genbank (Entrez)AB002377 AI565587 AK126888 AK293770 AK295813
RefSeq transcript (Entrez)NM_001195098 NM_001195099 NM_015199
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)ANKRD28
Cluster EST : UnigeneHs.335239 [ NCBI ]
CGAP (NCI)Hs.335239
Alternative Splicing GalleryENSG00000206560
Gene ExpressionANKRD28 [ NCBI-GEO ]   ANKRD28 [ EBI - ARRAY_EXPRESS ]   ANKRD28 [ SEEK ]   ANKRD28 [ MEM ]
Gene Expression Viewer (FireBrowse)ANKRD28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23243
GTEX Portal (Tissue expression)ANKRD28
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15084   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15084  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15084
Splice isoforms : SwissVarO15084
PhosPhoSitePlusO15084
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)Ank (PF00023)    Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam00023    pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)ANKRD28
DMDM Disease mutations23243
Blocks (Seattle)ANKRD28
SuperfamilyO15084
Human Protein AtlasENSG00000206560
Peptide AtlasO15084
HPRD10651
IPIIPI00477505   IPI00981632   IPI00514769   IPI01009712   IPI00791281   IPI00927832   IPI00908701   
Protein Interaction databases
DIP (DOE-UCLA)O15084
IntAct (EBI)O15084
FunCoupENSG00000206560
BioGRIDANKRD28
STRING (EMBL)ANKRD28
ZODIACANKRD28
Ontologies - Pathways
QuickGOO15084
Ontology : AmiGOGolgi membrane  protein binding  nucleoplasm  cytosol  COPII vesicle coating  
Ontology : EGO-EBIGolgi membrane  protein binding  nucleoplasm  cytosol  COPII vesicle coating  
NDEx NetworkANKRD28
Atlas of Cancer Signalling NetworkANKRD28
Wikipedia pathwaysANKRD28
Orthology - Evolution
OrthoDB23243
GeneTree (enSembl)ENSG00000206560
Phylogenetic Trees/Animal Genes : TreeFamANKRD28
HOVERGENO15084
HOGENOMO15084
Homologs : HomoloGeneANKRD28
Homology/Alignments : Family Browser (UCSC)ANKRD28
Gene fusions - Rearrangements
Fusion : MitelmanANKRD28/NUP98 [3p25.1/11p15.4]  
Fusion : MitelmanANKRD28/RFTN1 [3p25.1/3p25.1]  [t(3;3)(p24;p25)]  
Fusion: TCGAANKRD28 3p25.1 RFTN1 3p25.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANKRD28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANKRD28
dbVarANKRD28
ClinVarANKRD28
1000_GenomesANKRD28 
Exome Variant ServerANKRD28
ExAC (Exome Aggregation Consortium)ANKRD28 (select the gene name)
Genetic variants : HAPMAP23243
Genomic Variants (DGV)ANKRD28 [DGVbeta]
DECIPHER (Syndromes)3:15708744-15839691  ENSG00000206560
CONAN: Copy Number AnalysisANKRD28 
Mutations
ICGC Data PortalANKRD28 
TCGA Data PortalANKRD28 
Broad Tumor PortalANKRD28
OASIS PortalANKRD28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANKRD28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANKRD28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANKRD28
DgiDB (Drug Gene Interaction Database)ANKRD28
DoCM (Curated mutations)ANKRD28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANKRD28 (select a term)
intoGenANKRD28
Cancer3DANKRD28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611122   
Orphanet
MedgenANKRD28
Genetic Testing Registry ANKRD28
NextProtO15084 [Medical]
TSGene23243
GENETestsANKRD28
Huge Navigator ANKRD28 [HugePedia]
snp3D : Map Gene to Disease23243
BioCentury BCIQANKRD28
ClinGenANKRD28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23243
Chemical/Pharm GKB GenePA134880251
Clinical trialANKRD28
Miscellaneous
canSAR (ICR)ANKRD28 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANKRD28
EVEXANKRD28
GoPubMedANKRD28
iHOPANKRD28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:55:51 CET 2017

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