Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ANKRD6 (ankyrin repeat domain 6)

Identity

Alias_symbol (synonym)KIAA0957
Other alias-
HGNC (Hugo) ANKRD6
LocusID (NCBI) 22881
Atlas_Id 54960
Location 6q15  [Link to chromosome band 6q15]
Location_base_pair Starts at 89433178 and ends at 89633834 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKRD6 (6q15) / UBE3C (7q36.3)ANKRD6 (6q15) / ZDHHC14 (6q25.3)ANKRD6 6q15 / ZDHHC14 6q25.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(q15;q25) ANKRD6/ZDHHC14


External links

Nomenclature
HGNC (Hugo)ANKRD6   17280
Cards
Entrez_Gene (NCBI)ANKRD6  22881  ankyrin repeat domain 6
Aliases
GeneCards (Weizmann)ANKRD6
Ensembl hg19 (Hinxton)ENSG00000135299 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135299 [Gene_View]  ENSG00000135299 [Sequence]  chr6:89433178-89633834 [Contig_View]  ANKRD6 [Vega]
ICGC DataPortalENSG00000135299
TCGA cBioPortalANKRD6
AceView (NCBI)ANKRD6
Genatlas (Paris)ANKRD6
WikiGenes22881
SOURCE (Princeton)ANKRD6
Genetics Home Reference (NIH)ANKRD6
Genomic and cartography
GoldenPath hg38 (UCSC)ANKRD6  -     chr6:89433178-89633834 +  6q15   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANKRD6  -     6q15   [Description]    (hg19-Feb_2009)
EnsemblANKRD6 - 6q15 [CytoView hg19]  ANKRD6 - 6q15 [CytoView hg38]
Mapping of homologs : NCBIANKRD6 [Mapview hg19]  ANKRD6 [Mapview hg38]
OMIM610583   
Gene and transcription
Genbank (Entrez)AB023174 AK021550 AK022699 AK074189 AK092235
RefSeq transcript (Entrez)NM_001242809 NM_001242811 NM_001242813 NM_001242814 NM_014942
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ANKRD6
Cluster EST : UnigeneHs.702213 [ NCBI ]
CGAP (NCI)Hs.702213
Alternative Splicing GalleryENSG00000135299
Gene ExpressionANKRD6 [ NCBI-GEO ]   ANKRD6 [ EBI - ARRAY_EXPRESS ]   ANKRD6 [ SEEK ]   ANKRD6 [ MEM ]
Gene Expression Viewer (FireBrowse)ANKRD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22881
GTEX Portal (Tissue expression)ANKRD6
Human Protein AtlasENSG00000135299-ANKRD6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2G4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2G4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2G4
Splice isoforms : SwissVarQ9Y2G4
PhosPhoSitePlusQ9Y2G4
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)ANKRD6
DMDM Disease mutations22881
Blocks (Seattle)ANKRD6
SuperfamilyQ9Y2G4
Human Protein Atlas [tissue]ENSG00000135299-ANKRD6 [tissue]
Peptide AtlasQ9Y2G4
HPRD09798
IPIIPI00032135   IPI00218274   IPI00885007   IPI00976294   IPI00983720   IPI00982391   IPI00974158   IPI00974232   IPI00981332   IPI00978417   IPI00980329   IPI00979225   IPI00974513   IPI00978950   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2G4
IntAct (EBI)Q9Y2G4
FunCoupENSG00000135299
BioGRIDANKRD6
STRING (EMBL)ANKRD6
ZODIACANKRD6
Ontologies - Pathways
QuickGOQ9Y2G4
Ontology : AmiGOnucleus  cytoplasm  intracellular membrane-bounded organelle  positive regulation of JNK cascade  negative regulation of canonical Wnt signaling pathway  positive regulation of Wnt signaling pathway, planar cell polarity pathway  
Ontology : EGO-EBInucleus  cytoplasm  intracellular membrane-bounded organelle  positive regulation of JNK cascade  negative regulation of canonical Wnt signaling pathway  positive regulation of Wnt signaling pathway, planar cell polarity pathway  
NDEx NetworkANKRD6
Atlas of Cancer Signalling NetworkANKRD6
Wikipedia pathwaysANKRD6
Orthology - Evolution
OrthoDB22881
GeneTree (enSembl)ENSG00000135299
Phylogenetic Trees/Animal Genes : TreeFamANKRD6
HOVERGENQ9Y2G4
HOGENOMQ9Y2G4
Homologs : HomoloGeneANKRD6
Homology/Alignments : Family Browser (UCSC)ANKRD6
Gene fusions - Rearrangements
Fusion : MitelmanANKRD6/ZDHHC14 [6q15/6q25.3]  
Fusion PortalANKRD6 6q15 ZDHHC14 6q25.3 LGG
Fusion : QuiverANKRD6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANKRD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANKRD6
dbVarANKRD6
ClinVarANKRD6
1000_GenomesANKRD6 
Exome Variant ServerANKRD6
ExAC (Exome Aggregation Consortium)ENSG00000135299
GNOMAD BrowserENSG00000135299
Genetic variants : HAPMAP22881
Genomic Variants (DGV)ANKRD6 [DGVbeta]
DECIPHERANKRD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANKRD6 
Mutations
ICGC Data PortalANKRD6 
TCGA Data PortalANKRD6 
Broad Tumor PortalANKRD6
OASIS PortalANKRD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANKRD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANKRD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANKRD6
DgiDB (Drug Gene Interaction Database)ANKRD6
DoCM (Curated mutations)ANKRD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANKRD6 (select a term)
intoGenANKRD6
Cancer3DANKRD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610583   
Orphanet
DisGeNETANKRD6
MedgenANKRD6
Genetic Testing Registry ANKRD6
NextProtQ9Y2G4 [Medical]
TSGene22881
GENETestsANKRD6
Target ValidationANKRD6
Huge Navigator ANKRD6 [HugePedia]
snp3D : Map Gene to Disease22881
BioCentury BCIQANKRD6
ClinGenANKRD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22881
Chemical/Pharm GKB GenePA24807
Clinical trialANKRD6
Miscellaneous
canSAR (ICR)ANKRD6 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANKRD6
EVEXANKRD6
GoPubMedANKRD6
iHOPANKRD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:14:10 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.