Identity
HGNC
LOCATION
12q23.1
LOCUSID
ALIAS
AIDA,AIDA-1,ANKS2,EB-1,EB1,cajalin-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56899
MIM: 607815
HGNC: 24600
Ensembl: ENSG00000185046
Variants:
dbSNP: 56899
ClinVar: 56899
TCGA: ENSG00000185046
COSMIC: ANKS1B
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA162565877 | amisulpride | Chemical | ClinicalAnnotation | associated | PD | 28332719 | |
| PA166119022 | methamphetamine dependence | Disease | ClinicalAnnotation | associated | PD | 31462767 | |
| PA443309 | Alcoholism | Disease | ClinicalAnnotation | associated | PD | 31462767 | |
| PA444460 | Heroin Dependence | Disease | ClinicalAnnotation | associated | PD | 31462767 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 28332719 | |
| PA448073 | ethanol | Chemical | ClinicalAnnotation | associated | PD | 31462767 | |
| PA450403 | methamphetamine | Chemical | ClinicalAnnotation | associated | PD | 31462767 | |
| PA452619 | heroin | Chemical | ClinicalAnnotation | associated | PD | 31462767 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38759928 | 2024 | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity. | 0 |
| 38759928 | 2024 | AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity. | 0 |
| 37597021 | 2023 | Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells. | 0 |
| 37597021 | 2023 | Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells. | 0 |
| 33556191 | 2021 | Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-α expression. | 11 |
| 34781814 | 2021 | Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma. | 9 |
| 33556191 | 2021 | Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-α expression. | 11 |
| 34781814 | 2021 | Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma. | 9 |
| 31388001 | 2019 | Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome. | 14 |
| 31388001 | 2019 | Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome. | 14 |
| 30454010 | 2018 | The pro-metastasis effect of circANKS1B in breast cancer. | 159 |
| 30454010 | 2018 | The pro-metastasis effect of circANKS1B in breast cancer. | 159 |
| 28332719 | 2017 | rs7968606 polymorphism of ANKS1B is associated with improvement in the PANSS general score of schizophrenia caused by amisulpride. | 3 |
| 28332719 | 2017 | rs7968606 polymorphism of ANKS1B is associated with improvement in the PANSS general score of schizophrenia caused by amisulpride. | 3 |
| 24479813 | 2014 | ANKS1B is a smoking-related molecular alteration in clear cell renal cell carcinoma. | 29 |
Citation
Dessen P
ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40391/anks1b
