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ANO3 (anoctamin 3)

Identity

Alias (NCBI)C11orf25
DYT23
DYT24
GENX-3947
TMEM16C
HGNC (Hugo) ANO3
HGNC Alias symbGENX-3947
DYT23
HGNC Alias nametransmembrane protein 16C (eight membrane-spanning domains)
HGNC Previous nameC11orf25
 TMEM16C
HGNC Previous namechromosome 11 open reading frame 25
 transmembrane protein 16C
LocusID (NCBI) 63982
Atlas_Id 60377
Location 11p14.2  [Link to chromosome band 11p14]
Location_base_pair Starts at 26332130 and ends at 26663289 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALKBH3 (11p11.2) / ANO3 (11p14.2)ANO3 (11p14.2) / ANO3 (11p14.2)SMG1 (16p12.3) / ANO3 (11p14.2)
SMG1 ANO3ALKBH3 ANO3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ANO3   14004
Cards
Entrez_Gene (NCBI)ANO3    anoctamin 3
AliasesC11orf25; DYT23; DYT24; GENX-3947; 
TMEM16C
GeneCards (Weizmann)ANO3
Ensembl hg19 (Hinxton)ENSG00000134343 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134343 [Gene_View]  ENSG00000134343 [Sequence]  chr11:26332130-26663289 [Contig_View]  ANO3 [Vega]
ICGC DataPortalENSG00000134343
TCGA cBioPortalANO3
AceView (NCBI)ANO3
Genatlas (Paris)ANO3
SOURCE (Princeton)ANO3
Genetics Home Reference (NIH)ANO3
Genomic and cartography
GoldenPath hg38 (UCSC)ANO3  -     chr11:26332130-26663289 +  11p14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANO3  -     11p14.2   [Description]    (hg19-Feb_2009)
GoldenPathANO3 - 11p14.2 [CytoView hg19]  ANO3 - 11p14.2 [CytoView hg38]
ImmunoBaseENSG00000134343
Genome Data Viewer NCBIANO3 [Mapview hg19]  
OMIM610110   615034   
Gene and transcription
Genbank (Entrez)AJ300461 AK295143 AK295658 AK295816 AK302659
RefSeq transcript (Entrez)NM_001313726 NM_001313727 NM_031418
Consensus coding sequences : CCDS (NCBI)ANO3
Gene ExpressionANO3 [ NCBI-GEO ]   ANO3 [ EBI - ARRAY_EXPRESS ]   ANO3 [ SEEK ]   ANO3 [ MEM ]
Gene Expression Viewer (FireBrowse)ANO3 [ Firebrowse - Broad ]
GenevisibleExpression of ANO3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63982
GTEX Portal (Tissue expression)ANO3
Human Protein AtlasENSG00000134343-ANO3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYT9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYT9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYT9
PhosPhoSitePlusQ9BYT9
Domains : Interpro (EBI)Anoct_dimer    Anoctamin    Anoctamin-3   
Domain families : Pfam (Sanger)Anoct_dimer (PF16178)    Anoctamin (PF04547)   
Domain families : Pfam (NCBI)pfam16178    pfam04547   
Conserved Domain (NCBI)ANO3
SuperfamilyQ9BYT9
AlphaFold pdb e-kbQ9BYT9   
Human Protein Atlas [tissue]ENSG00000134343-ANO3 [tissue]
HPRD15526
Protein Interaction databases
DIP (DOE-UCLA)Q9BYT9
IntAct (EBI)Q9BYT9
BioGRIDANO3
STRING (EMBL)ANO3
ZODIACANO3
Ontologies - Pathways
QuickGOQ9BYT9
Ontology : AmiGOintracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  integral component of membrane  detection of temperature stimulus  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  detection of mechanical stimulus  transmembrane transport  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
Ontology : EGO-EBIintracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  integral component of membrane  detection of temperature stimulus  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  detection of mechanical stimulus  transmembrane transport  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
NDEx NetworkANO3
Atlas of Cancer Signalling NetworkANO3
Wikipedia pathwaysANO3
Orthology - Evolution
OrthoDB63982
GeneTree (enSembl)ENSG00000134343
Phylogenetic Trees/Animal Genes : TreeFamANO3
Homologs : HomoloGeneANO3
Homology/Alignments : Family Browser (UCSC)ANO3
Gene fusions - Rearrangements
Fusion : QuiverANO3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANO3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANO3
dbVarANO3
ClinVarANO3
MonarchANO3
1000_GenomesANO3 
Exome Variant ServerANO3
GNOMAD BrowserENSG00000134343
Varsome BrowserANO3
ACMGANO3 variants
VarityQ9BYT9
Genomic Variants (DGV)ANO3 [DGVbeta]
DECIPHERANO3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANO3 
Mutations
ICGC Data PortalANO3 
TCGA Data PortalANO3 
Broad Tumor PortalANO3
OASIS PortalANO3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANO3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANO3
Mutations and Diseases : HGMDANO3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANO3
DgiDB (Drug Gene Interaction Database)ANO3
DoCM (Curated mutations)ANO3
CIViC (Clinical Interpretations of Variants in Cancer)ANO3
Cancer3DANO3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610110    615034   
Orphanet23108   
DisGeNETANO3
MedgenANO3
Genetic Testing Registry ANO3
NextProtQ9BYT9 [Medical]
GENETestsANO3
Target ValidationANO3
Huge Navigator ANO3 [HugePedia]
ClinGenANO3
Clinical trials, drugs, therapy
MyCancerGenomeANO3
Protein Interactions : CTDANO3
Pharm GKB GenePA25489
PharosQ9BYT9
Clinical trialANO3
Miscellaneous
canSAR (ICR)ANO3
HarmonizomeANO3
DataMed IndexANO3
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANO3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:42:13 CEST 2021

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