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ANO4 (anoctamin 4)

Identity

Alias (NCBI)TMEM16D
HGNC (Hugo) ANO4
HGNC Alias symbFLJ34221
FLJ34272
FLJ35277
HGNC Previous nameTMEM16D
HGNC Previous nametransmembrane protein 16D
LocusID (NCBI) 121601
Atlas_Id 58177
Location 12q23.1  [Link to chromosome band 12q23]
Location_base_pair Starts at 100794776 and ends at 101128629 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKS1B (12q23.1) / ANO4 (12q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ANO4   23837
Cards
Entrez_Gene (NCBI)ANO4    anoctamin 4
AliasesTMEM16D
GeneCards (Weizmann)ANO4
Ensembl hg19 (Hinxton)ENSG00000151572 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151572 [Gene_View]  ENSG00000151572 [Sequence]  chr12:100794776-101128629 [Contig_View]  ANO4 [Vega]
ICGC DataPortalENSG00000151572
TCGA cBioPortalANO4
AceView (NCBI)ANO4
Genatlas (Paris)ANO4
SOURCE (Princeton)ANO4
Genetics Home Reference (NIH)ANO4
Genomic and cartography
GoldenPath hg38 (UCSC)ANO4  -     chr12:100794776-101128629 +  12q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANO4  -     12q23.1   [Description]    (hg19-Feb_2009)
GoldenPathANO4 - 12q23.1 [CytoView hg19]  ANO4 - 12q23.1 [CytoView hg38]
ImmunoBaseENSG00000151572
Genome Data Viewer NCBIANO4 [Mapview hg19]  
OMIM610111   
Gene and transcription
Genbank (Entrez)AI140598 AK091540 AK091591 AK092596 AK293810
RefSeq transcript (Entrez)NM_001286615 NM_001286616 NM_178826
Consensus coding sequences : CCDS (NCBI)ANO4
Gene ExpressionANO4 [ NCBI-GEO ]   ANO4 [ EBI - ARRAY_EXPRESS ]   ANO4 [ SEEK ]   ANO4 [ MEM ]
Gene Expression Viewer (FireBrowse)ANO4 [ Firebrowse - Broad ]
GenevisibleExpression of ANO4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121601
GTEX Portal (Tissue expression)ANO4
Human Protein AtlasENSG00000151572-ANO4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ32M45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ32M45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ32M45
PhosPhoSitePlusQ32M45
Domains : Interpro (EBI)Anoct_dimer    Anoctamin    Anoctamin-4   
Domain families : Pfam (Sanger)Anoct_dimer (PF16178)    Anoctamin (PF04547)   
Domain families : Pfam (NCBI)pfam16178    pfam04547   
Conserved Domain (NCBI)ANO4
SuperfamilyQ32M45
AlphaFold pdb e-kbQ32M45   
Human Protein Atlas [tissue]ENSG00000151572-ANO4 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q32M45
IntAct (EBI)Q32M45
BioGRIDANO4
STRING (EMBL)ANO4
ZODIACANO4
Ontologies - Pathways
QuickGOQ32M45
Ontology : AmiGOintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  plasma membrane  chloride transport  integral component of membrane  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  transmembrane transport  calcium activated phosphatidylserine scrambling  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
Ontology : EGO-EBIintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  chloride channel activity  plasma membrane  plasma membrane  plasma membrane  chloride transport  integral component of membrane  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  transmembrane transport  calcium activated phosphatidylserine scrambling  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
NDEx NetworkANO4
Atlas of Cancer Signalling NetworkANO4
Wikipedia pathwaysANO4
Orthology - Evolution
OrthoDB121601
GeneTree (enSembl)ENSG00000151572
Phylogenetic Trees/Animal Genes : TreeFamANO4
Homologs : HomoloGeneANO4
Homology/Alignments : Family Browser (UCSC)ANO4
Gene fusions - Rearrangements
Fusion : QuiverANO4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANO4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANO4
dbVarANO4
ClinVarANO4
MonarchANO4
1000_GenomesANO4 
Exome Variant ServerANO4
GNOMAD BrowserENSG00000151572
Varsome BrowserANO4
ACMGANO4 variants
VarityQ32M45
Genomic Variants (DGV)ANO4 [DGVbeta]
DECIPHERANO4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANO4 
Mutations
ICGC Data PortalANO4 
TCGA Data PortalANO4 
Broad Tumor PortalANO4
OASIS PortalANO4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANO4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANO4
Mutations and Diseases : HGMDANO4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANO4
DgiDB (Drug Gene Interaction Database)ANO4
DoCM (Curated mutations)ANO4
CIViC (Clinical Interpretations of Variants in Cancer)ANO4
Cancer3DANO4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610111   
Orphanet
DisGeNETANO4
MedgenANO4
Genetic Testing Registry ANO4
NextProtQ32M45 [Medical]
GENETestsANO4
Target ValidationANO4
Huge Navigator ANO4 [HugePedia]
ClinGenANO4
Clinical trials, drugs, therapy
MyCancerGenomeANO4
Protein Interactions : CTDANO4
PharosQ32M45
Clinical trialANO4
Miscellaneous
canSAR (ICR)ANO4
HarmonizomeANO4
DataMed IndexANO4
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANO4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:29 CEST 2021

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