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ANO4 (anoctamin 4)

Identity

Alias_namesTMEM16D
transmembrane protein 16D
Alias_symbol (synonym)FLJ34221
FLJ34272
FLJ35277
Other alias
HGNC (Hugo) ANO4
LocusID (NCBI) 121601
Atlas_Id 60378
Location 12q23.1  [Link to chromosome band 12q23]
Location_base_pair Starts at 100794596 and ends at 101128641 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANKS1B (12q23.1) / ANO4 (12q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANO4   23837
Cards
Entrez_Gene (NCBI)ANO4  121601  anoctamin 4
AliasesTMEM16D
GeneCards (Weizmann)ANO4
Ensembl hg19 (Hinxton)ENSG00000151572 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151572 [Gene_View]  chr12:100794596-101128641 [Contig_View]  ANO4 [Vega]
ICGC DataPortalENSG00000151572
TCGA cBioPortalANO4
AceView (NCBI)ANO4
Genatlas (Paris)ANO4
WikiGenes121601
SOURCE (Princeton)ANO4
Genetics Home Reference (NIH)ANO4
Genomic and cartography
GoldenPath hg38 (UCSC)ANO4  -     chr12:100794596-101128641 +  12q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANO4  -     12q23.1   [Description]    (hg19-Feb_2009)
EnsemblANO4 - 12q23.1 [CytoView hg19]  ANO4 - 12q23.1 [CytoView hg38]
Mapping of homologs : NCBIANO4 [Mapview hg19]  ANO4 [Mapview hg38]
OMIM610111   
Gene and transcription
Genbank (Entrez)AI140598 AK091540 AK091591 AK092596 AK293810
RefSeq transcript (Entrez)NM_001286615 NM_001286616 NM_178826
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ANO4
Cluster EST : UnigeneHs.58785 [ NCBI ]
CGAP (NCI)Hs.58785
Alternative Splicing GalleryENSG00000151572
Gene ExpressionANO4 [ NCBI-GEO ]   ANO4 [ EBI - ARRAY_EXPRESS ]   ANO4 [ SEEK ]   ANO4 [ MEM ]
Gene Expression Viewer (FireBrowse)ANO4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121601
GTEX Portal (Tissue expression)ANO4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ32M45   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ32M45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ32M45
Splice isoforms : SwissVarQ32M45
PhosPhoSitePlusQ32M45
Domains : Interpro (EBI)Anoct_dimer    Anoctamin    Anoctamin-4   
Domain families : Pfam (Sanger)Anoct_dimer (PF16178)    Anoctamin (PF04547)   
Domain families : Pfam (NCBI)pfam16178    pfam04547   
Conserved Domain (NCBI)ANO4
DMDM Disease mutations121601
Blocks (Seattle)ANO4
SuperfamilyQ32M45
Human Protein AtlasENSG00000151572
Peptide AtlasQ32M45
HPRD15527
IPIIPI00249140   IPI00847500   IPI00177878   IPI00921990   IPI01023057   IPI01022461   
Protein Interaction databases
DIP (DOE-UCLA)Q32M45
IntAct (EBI)Q32M45
FunCoupENSG00000151572
BioGRIDANO4
STRING (EMBL)ANO4
ZODIACANO4
Ontologies - Pathways
QuickGOQ32M45
Ontology : AmiGOintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  intracellular  plasma membrane  plasma membrane  chloride transport  lipid transport  integral component of membrane  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  calcium activated phosphatidylserine scrambling  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
Ontology : EGO-EBIintracellular calcium activated chloride channel activity  intracellular calcium activated chloride channel activity  intracellular  plasma membrane  plasma membrane  chloride transport  lipid transport  integral component of membrane  phospholipid scramblase activity  ion transmembrane transport  protein dimerization activity  calcium activated phosphatidylserine scrambling  calcium activated phosphatidylcholine scrambling  calcium activated galactosylceramide scrambling  chloride transmembrane transport  
NDEx NetworkANO4
Atlas of Cancer Signalling NetworkANO4
Wikipedia pathwaysANO4
Orthology - Evolution
OrthoDB121601
GeneTree (enSembl)ENSG00000151572
Phylogenetic Trees/Animal Genes : TreeFamANO4
HOVERGENQ32M45
HOGENOMQ32M45
Homologs : HomoloGeneANO4
Homology/Alignments : Family Browser (UCSC)ANO4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANO4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANO4
dbVarANO4
ClinVarANO4
1000_GenomesANO4 
Exome Variant ServerANO4
ExAC (Exome Aggregation Consortium)ANO4 (select the gene name)
Genetic variants : HAPMAP121601
Genomic Variants (DGV)ANO4 [DGVbeta]
DECIPHERANO4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANO4 
Mutations
ICGC Data PortalANO4 
TCGA Data PortalANO4 
Broad Tumor PortalANO4
OASIS PortalANO4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANO4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANO4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANO4
DgiDB (Drug Gene Interaction Database)ANO4
DoCM (Curated mutations)ANO4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANO4 (select a term)
intoGenANO4
Cancer3DANO4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610111   
Orphanet
MedgenANO4
Genetic Testing Registry ANO4
NextProtQ32M45 [Medical]
TSGene121601
GENETestsANO4
Target ValidationANO4
Huge Navigator ANO4 [HugePedia]
snp3D : Map Gene to Disease121601
BioCentury BCIQANO4
ClinGenANO4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD121601
Chemical/Pharm GKB GenePA164715582
Clinical trialANO4
Miscellaneous
canSAR (ICR)ANO4 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANO4
EVEXANO4
GoPubMedANO4
iHOPANO4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:29 CEST 2017

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