Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ANTXR1 (anthrax toxin receptor 1)

Identity

Alias_symbol (synonym)TEM8
FLJ21776
FLJ10601
ATR
Other aliasGAPO
HGNC (Hugo) ANTXR1
LocusID (NCBI) 84168
Atlas_Id 652
Location 2p13.3  [Link to chromosome band 2p13]
Location_base_pair Starts at 69240276 and ends at 69373496 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANTXR1 (2p13.3) / APLF (2p13.3)ANTXR1 (2p13.3) / NCOA3 (20q13.12)AUTS2 (7q11.22) / ANTXR1 (2p13.3)
MAPK8IP3 (16p13.3) / ANTXR1 (2p13.3)MXD1 (2p13.3) / ANTXR1 (2p13.3)ANTXR1 2p13.3 / APLF 2p13.3
MXD1 2p13.3 / ANTXR1 2p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANTXR1   21014
Cards
Entrez_Gene (NCBI)ANTXR1  84168  anthrax toxin receptor 1
AliasesATR; GAPO; TEM8
GeneCards (Weizmann)ANTXR1
Ensembl hg19 (Hinxton)ENSG00000169604 [Gene_View]  chr2:69240276-69373496 [Contig_View]  ANTXR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000169604 [Gene_View]  chr2:69240276-69373496 [Contig_View]  ANTXR1 [Vega]
ICGC DataPortalENSG00000169604
TCGA cBioPortalANTXR1
AceView (NCBI)ANTXR1
Genatlas (Paris)ANTXR1
WikiGenes84168
SOURCE (Princeton)ANTXR1
Genetics Home Reference (NIH)ANTXR1
Genomic and cartography
GoldenPath hg19 (UCSC)ANTXR1  -     chr2:69240276-69373496 +  2p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANTXR1  -     2p13.3   [Description]    (hg38-Dec_2013)
EnsemblANTXR1 - 2p13.3 [CytoView hg19]  ANTXR1 - 2p13.3 [CytoView hg38]
Mapping of homologs : NCBIANTXR1 [Mapview hg19]  ANTXR1 [Mapview hg38]
OMIM230740   602089   606410   
Gene and transcription
Genbank (Entrez)AF090095 AF279145 AF421380 AK001463 AK002160
RefSeq transcript (Entrez)NM_018153 NM_032208 NM_053034
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_012649 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)ANTXR1
Cluster EST : UnigeneHs.165859 [ NCBI ]
CGAP (NCI)Hs.165859
Alternative Splicing GalleryENSG00000169604
Gene ExpressionANTXR1 [ NCBI-GEO ]   ANTXR1 [ EBI - ARRAY_EXPRESS ]   ANTXR1 [ SEEK ]   ANTXR1 [ MEM ]
Gene Expression Viewer (FireBrowse)ANTXR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84168
GTEX Portal (Tissue expression)ANTXR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6X2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H6X2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H6X2
Splice isoforms : SwissVarQ9H6X2
PhosPhoSitePlusQ9H6X2
Domaine pattern : Prosite (Expaxy)VWFA (PS50234)   
Domains : Interpro (EBI)Anthrax_toxin_rcpt    Anthrax_toxin_rcpt_C    Anthrax_toxin_rcpt_extracel    VWF_A   
Domain families : Pfam (Sanger)Ant_C (PF05586)    Anth_Ig (PF05587)    VWA (PF00092)   
Domain families : Pfam (NCBI)pfam05586    pfam05587    pfam00092   
Domain families : Smart (EMBL)VWA (SM00327)  
Domain structure : Prodom (Prabi Lyon)Anthrax_toxin_rcpt_C (PD377005)   
Conserved Domain (NCBI)ANTXR1
DMDM Disease mutations84168
Blocks (Seattle)ANTXR1
PDB (SRS)3N2N   
PDB (PDBSum)3N2N   
PDB (IMB)3N2N   
PDB (RSDB)3N2N   
Structural Biology KnowledgeBase3N2N   
SCOP (Structural Classification of Proteins)3N2N   
CATH (Classification of proteins structures)3N2N   
SuperfamilyQ9H6X2
Human Protein AtlasENSG00000169604
Peptide AtlasQ9H6X2
HPRD05913
IPIIPI00030431   IPI00071177   IPI00219619   IPI00871735   IPI00969452   IPI00816778   IPI00979310   
Protein Interaction databases
DIP (DOE-UCLA)Q9H6X2
IntAct (EBI)Q9H6X2
FunCoupENSG00000169604
BioGRIDANTXR1
STRING (EMBL)ANTXR1
ZODIACANTXR1
Ontologies - Pathways
QuickGOQ9H6X2
Ontology : AmiGOtransmembrane signaling receptor activity  protein binding  collagen binding  plasma membrane  signal transduction  cell surface  endosome membrane  integral component of membrane  reproductive process  lamellipodium membrane  filopodium membrane  actin cytoskeleton reorganization  substrate adhesion-dependent cell spreading  metal ion binding  actin filament binding  extracellular exosome  
Ontology : EGO-EBItransmembrane signaling receptor activity  protein binding  collagen binding  plasma membrane  signal transduction  cell surface  endosome membrane  integral component of membrane  reproductive process  lamellipodium membrane  filopodium membrane  actin cytoskeleton reorganization  substrate adhesion-dependent cell spreading  metal ion binding  actin filament binding  extracellular exosome  
NDEx NetworkANTXR1
Atlas of Cancer Signalling NetworkANTXR1
Wikipedia pathwaysANTXR1
Orthology - Evolution
OrthoDB84168
GeneTree (enSembl)ENSG00000169604
Phylogenetic Trees/Animal Genes : TreeFamANTXR1
HOVERGENQ9H6X2
HOGENOMQ9H6X2
Homologs : HomoloGeneANTXR1
Homology/Alignments : Family Browser (UCSC)ANTXR1
Gene fusions - Rearrangements
Fusion : MitelmanANTXR1/APLF [2p13.3/2p13.3]  
Fusion : MitelmanMXD1/ANTXR1 [2p13.3/2p13.3]  [t(2;2)(p13;p13)]  
Fusion: TCGAANTXR1 2p13.3 APLF 2p13.3 OV
Fusion: TCGAMXD1 2p13.3 ANTXR1 2p13.3 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANTXR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANTXR1
dbVarANTXR1
ClinVarANTXR1
1000_GenomesANTXR1 
Exome Variant ServerANTXR1
ExAC (Exome Aggregation Consortium)ANTXR1 (select the gene name)
Genetic variants : HAPMAP84168
Genomic Variants (DGV)ANTXR1 [DGVbeta]
DECIPHER (Syndromes)2:69240276-69373496  ENSG00000169604
CONAN: Copy Number AnalysisANTXR1 
Mutations
ICGC Data PortalANTXR1 
TCGA Data PortalANTXR1 
Broad Tumor PortalANTXR1
OASIS PortalANTXR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANTXR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANTXR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ANTXR1
DgiDB (Drug Gene Interaction Database)ANTXR1
DoCM (Curated mutations)ANTXR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANTXR1 (select a term)
intoGenANTXR1
Cancer3DANTXR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM230740    602089    606410   
Orphanet1985   
MedgenANTXR1
Genetic Testing Registry ANTXR1
NextProtQ9H6X2 [Medical]
TSGene84168
GENETestsANTXR1
Huge Navigator ANTXR1 [HugePedia]
snp3D : Map Gene to Disease84168
BioCentury BCIQANTXR1
ClinGenANTXR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84168
Chemical/Pharm GKB GenePA134956382
Clinical trialANTXR1
Miscellaneous
canSAR (ICR)ANTXR1 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANTXR1
EVEXANTXR1
GoPubMedANTXR1
iHOPANTXR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:55:56 CET 2017

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