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ANTXR2 (anthrax toxin receptor 2)

Identity

Alias_symbol (synonym)CMG2
CMG-2
FLJ31074
Other aliasHFS
ISH
JHF
HGNC (Hugo) ANTXR2
LocusID (NCBI) 118429
Atlas_Id 54049
Location 4q21.21  [Link to chromosome band 4q21]
Location_base_pair Starts at 80898662 and ends at 80994477 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ANTXR2 (4q21.21) / ANTXR2 (4q21.21)ANTXR2 (4q21.21) / IGFBP3 (7p12.3)ANTXR2 (4q21.21) / RNF111 (15q22.1)
IGFBP3 (7p12.3) / ANTXR2 (4q21.21)NPLOC4 (17q25.3) / ANTXR2 (4q21.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ANTXR2   21732
Cards
Entrez_Gene (NCBI)ANTXR2  118429  anthrax toxin receptor 2
AliasesCMG-2; CMG2; HFS; ISH; 
JHF
GeneCards (Weizmann)ANTXR2
Ensembl hg19 (Hinxton)ENSG00000163297 [Gene_View]  chr4:80898662-80994477 [Contig_View]  ANTXR2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163297 [Gene_View]  chr4:80898662-80994477 [Contig_View]  ANTXR2 [Vega]
ICGC DataPortalENSG00000163297
TCGA cBioPortalANTXR2
AceView (NCBI)ANTXR2
Genatlas (Paris)ANTXR2
WikiGenes118429
SOURCE (Princeton)ANTXR2
Genetics Home Reference (NIH)ANTXR2
Genomic and cartography
GoldenPath hg19 (UCSC)ANTXR2  -     chr4:80898662-80994477 -  4q21.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ANTXR2  -     4q21.21   [Description]    (hg38-Dec_2013)
EnsemblANTXR2 - 4q21.21 [CytoView hg19]  ANTXR2 - 4q21.21 [CytoView hg38]
Mapping of homologs : NCBIANTXR2 [Mapview hg19]  ANTXR2 [Mapview hg38]
OMIM228600   608041   
Gene and transcription
Genbank (Entrez)AB209913 AK023450 AK055636 AL110207 AL831848
RefSeq transcript (Entrez)NM_001145794 NM_001286780 NM_001286781 NM_058172
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_015987 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)ANTXR2
Cluster EST : UnigeneHs.162963 [ NCBI ]
CGAP (NCI)Hs.162963
Alternative Splicing GalleryENSG00000163297
Gene ExpressionANTXR2 [ NCBI-GEO ]   ANTXR2 [ EBI - ARRAY_EXPRESS ]   ANTXR2 [ SEEK ]   ANTXR2 [ MEM ]
Gene Expression Viewer (FireBrowse)ANTXR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118429
GTEX Portal (Tissue expression)ANTXR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP58335   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP58335  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP58335
Splice isoforms : SwissVarP58335
PhosPhoSitePlusP58335
Domaine pattern : Prosite (Expaxy)VWFA (PS50234)   
Domains : Interpro (EBI)Anthrax_toxin_rcpt    Anthrax_toxin_rcpt_C    Anthrax_toxin_rcpt_extracel    VWF_A   
Domain families : Pfam (Sanger)Ant_C (PF05586)    Anth_Ig (PF05587)    VWA (PF00092)   
Domain families : Pfam (NCBI)pfam05586    pfam05587    pfam00092   
Domain families : Smart (EMBL)VWA (SM00327)  
Domain structure : Prodom (Prabi Lyon)Anthrax_toxin_rcpt_C (PD377005)   
Conserved Domain (NCBI)ANTXR2
DMDM Disease mutations118429
Blocks (Seattle)ANTXR2
PDB (SRS)1SHT    1SHU    1T6B    1TZN   
PDB (PDBSum)1SHT    1SHU    1T6B    1TZN   
PDB (IMB)1SHT    1SHU    1T6B    1TZN   
PDB (RSDB)1SHT    1SHU    1T6B    1TZN   
Structural Biology KnowledgeBase1SHT    1SHU    1T6B    1TZN   
SCOP (Structural Classification of Proteins)1SHT    1SHU    1T6B    1TZN   
CATH (Classification of proteins structures)1SHT    1SHU    1T6B    1TZN   
SuperfamilyP58335
Human Protein AtlasENSG00000163297
Peptide AtlasP58335
HPRD07452
IPIIPI00375552   IPI00036552   IPI00375555   IPI00375556   IPI00894466   
Protein Interaction databases
DIP (DOE-UCLA)P58335
IntAct (EBI)P58335
FunCoupENSG00000163297
BioGRIDANTXR2
STRING (EMBL)ANTXR2
ZODIACANTXR2
Ontologies - Pathways
QuickGOP58335
Ontology : AmiGOreceptor activity  protein binding  extracellular region  endoplasmic reticulum membrane  plasma membrane  external side of plasma membrane  endosome membrane  integral component of membrane  reproductive process  metal ion binding  toxin transport  
Ontology : EGO-EBIreceptor activity  protein binding  extracellular region  endoplasmic reticulum membrane  plasma membrane  external side of plasma membrane  endosome membrane  integral component of membrane  reproductive process  metal ion binding  toxin transport  
NDEx NetworkANTXR2
Atlas of Cancer Signalling NetworkANTXR2
Wikipedia pathwaysANTXR2
Orthology - Evolution
OrthoDB118429
GeneTree (enSembl)ENSG00000163297
Phylogenetic Trees/Animal Genes : TreeFamANTXR2
HOVERGENP58335
HOGENOMP58335
Homologs : HomoloGeneANTXR2
Homology/Alignments : Family Browser (UCSC)ANTXR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANTXR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANTXR2
dbVarANTXR2
ClinVarANTXR2
1000_GenomesANTXR2 
Exome Variant ServerANTXR2
ExAC (Exome Aggregation Consortium)ANTXR2 (select the gene name)
Genetic variants : HAPMAP118429
Genomic Variants (DGV)ANTXR2 [DGVbeta]
DECIPHER (Syndromes)4:80898662-80994477  ENSG00000163297
CONAN: Copy Number AnalysisANTXR2 
Mutations
ICGC Data PortalANTXR2 
TCGA Data PortalANTXR2 
Broad Tumor PortalANTXR2
OASIS PortalANTXR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANTXR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDANTXR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch ANTXR2
DgiDB (Drug Gene Interaction Database)ANTXR2
DoCM (Curated mutations)ANTXR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ANTXR2 (select a term)
intoGenANTXR2
Cancer3DANTXR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM228600    608041   
Orphanet1959    2069   
MedgenANTXR2
Genetic Testing Registry ANTXR2
NextProtP58335 [Medical]
TSGene118429
GENETestsANTXR2
Huge Navigator ANTXR2 [HugePedia]
snp3D : Map Gene to Disease118429
BioCentury BCIQANTXR2
ClinGenANTXR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD118429
Chemical/Pharm GKB GenePA128394752
Clinical trialANTXR2
Miscellaneous
canSAR (ICR)ANTXR2 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineANTXR2
EVEXANTXR2
GoPubMedANTXR2
iHOPANTXR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:55:56 CET 2017

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