ANXA3 (annexin A3)

2010-04-01  

Identity

HGNC
ANXA3
LOCATION
4q21.21
LOCUSID
306
ALIAS
ANX3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 306
MIM: 106490
HGNC: 541
Ensembl: ENSG00000138772

Variants:

dbSNP: 306
ClinVar: 306
TCGA: ENSG00000138772
COSMIC: ANXA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138772ENST00000264908P12429
ENSG00000138772ENST00000503570D6RA82
ENSG00000138772ENST00000508214D6RCA8
ENSG00000138772ENST00000512373D6RAZ8
ENSG00000138772ENST00000512542D6RFJ9
ENSG00000138772ENST00000512884D6RA82
ENSG00000138772ENST00000514171D6RFG5

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
214351742012Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients.31
201036352010Increased expression of annexin A3 is a mechanism of platinum resistance in ovarian cancer.28
162362642005Annexin A3 is a potential angiogenic mediator.26
230118542013The role of annexin A3 playing in cancers.25
221899132012Proteomic investigation of 5-fluorouracil resistance in a human hepatocellular carcinoma cell line.19
260956092015ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma.19
243754742015Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma.18
252672732015Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells.15
236318202013Annexin A3 is associated with a poor prognosis in breast cancer and participates in the modulation of apoptosis in vitro by affecting the Bcl-2/Bax balance.13
276536862016Quantitative Lipid Droplet Proteome Analysis Identifies Annexin A3 as a Cofactor for HCV Particle Production.13

Citation

Dessen P

ANXA3 (annexin A3)

Atlas Genet Cytogenet Oncol Haematol. 2010-04-01

Online version: http://atlasgeneticsoncology.org/gene/51407/anxa3