Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

ANXA5 (annexin A5)

Identity

Alias (NCBI)ANX5
CPB-I
ENX2
HEL-S-7
PP4
RPRGL3
VAC-alph
HGNC (Hugo) ANXA5
HGNC Previous nameENX2
 ANX5
LocusID (NCBI) 308
Atlas_Id 656
Location 4q27  [Link to chromosome band 4q27]
Location_base_pair Starts at 121667946 and ends at 121696980 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANXA5 (4q27)::ANXA5 (4q27)ANXA5 (4q27)::CLASP2 (3p22.3)ANXA5 (4q27)::INO80C (18q12.2)
ANXA5 (4q27)::USP48 (1p36.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ANXA5   543
LRG (Locus Reference Genomic)LRG_606
Cards
Entrez_Gene (NCBI)ANXA5    annexin A5
AliasesANX5; CPB-I; ENX2; HEL-S-7; 
PP4; RPRGL3; VAC-alph
GeneCards (Weizmann)ANXA5
Ensembl hg19 (Hinxton)ENSG00000164111 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164111 [Gene_View]  ENSG00000164111 [Sequence]  chr4:121667946-121696980 [Contig_View]  ANXA5 [Vega]
ICGC DataPortalENSG00000164111
TCGA cBioPortalANXA5
AceView (NCBI)ANXA5
Genatlas (Paris)ANXA5
SOURCE (Princeton)ANXA5
Genetics Home Reference (NIH)ANXA5
Genomic and cartography
GoldenPath hg38 (UCSC)ANXA5  -     chr4:121667946-121696980 -  4q27   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANXA5  -     4q27   [Description]    (hg19-Feb_2009)
GoldenPathANXA5 - 4q27 [CytoView hg19]  ANXA5 - 4q27 [CytoView hg38]
ImmunoBaseENSG00000164111
Genome Data Viewer NCBIANXA5 [Mapview hg19]  
OMIM131230   614391   
Gene and transcription
Genbank (Entrez)AK297909 AK312644 AY577779 BC001429 BC004993
RefSeq transcript (Entrez)NM_001154
Consensus coding sequences : CCDS (NCBI)ANXA5
Gene ExpressionANXA5 [ NCBI-GEO ]   ANXA5 [ EBI - ARRAY_EXPRESS ]   ANXA5 [ SEEK ]   ANXA5 [ MEM ]
Gene Expression Viewer (FireBrowse)ANXA5 [ Firebrowse - Broad ]
GenevisibleExpression of ANXA5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)308
GTEX Portal (Tissue expression)ANXA5
Human Protein AtlasENSG00000164111-ANXA5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08758   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08758  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08758
PhosPhoSitePlusP08758
Domaine pattern : Prosite (Expaxy)ANNEXIN_1 (PS00223)    ANNEXIN_2 (PS51897)   
Domains : Interpro (EBI)Annexin    Annexin_repeat    Annexin_repeat_CS    Annexin_sf    ANX5   
Domain families : Pfam (Sanger)Annexin (PF00191)   
Domain families : Pfam (NCBI)pfam00191   
Domain families : Smart (EMBL)ANX (SM00335)  
Conserved Domain (NCBI)ANXA5
PDB (RSDB)1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
PDB Europe1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
PDB (PDBSum)1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
PDB (IMB)1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
Structural Biology KnowledgeBase1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
SCOP (Structural Classification of Proteins)1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
CATH (Classification of proteins structures)1ANW    1ANX    1AVH    1AVR    1HAK    1HVD    1HVE    1HVF    1HVG    1SAV    2XO2    2XO3    6K22    6K25   
SuperfamilyP08758
AlphaFold pdb e-kbP08758   
Human Protein Atlas [tissue]ENSG00000164111-ANXA5 [tissue]
HPRD00568
Protein Interaction databases
DIP (DOE-UCLA)P08758
IntAct (EBI)P08758
BioGRIDANXA5
STRING (EMBL)ANXA5
ZODIACANXA5
Ontologies - Pathways
QuickGOP08758
Ontology : AmiGOphospholipase inhibitor activity  calcium ion binding  protein binding  phospholipid binding  calcium-dependent phospholipid binding  extracellular region  cytoplasm  cytoplasm  cytosol  focal adhesion  signal transduction  blood coagulation  external side of plasma membrane  response to organic substance  membrane  negative regulation of apoptotic process  negative regulation of catalytic activity  negative regulation of coagulation  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  endothelial microparticle  
Ontology : EGO-EBIphospholipase inhibitor activity  calcium ion binding  protein binding  phospholipid binding  calcium-dependent phospholipid binding  extracellular region  cytoplasm  cytoplasm  cytosol  focal adhesion  signal transduction  blood coagulation  external side of plasma membrane  response to organic substance  membrane  negative regulation of apoptotic process  negative regulation of catalytic activity  negative regulation of coagulation  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  endothelial microparticle  
NDEx NetworkANXA5
Atlas of Cancer Signalling NetworkANXA5
Wikipedia pathwaysANXA5
Orthology - Evolution
OrthoDB308
GeneTree (enSembl)ENSG00000164111
Phylogenetic Trees/Animal Genes : TreeFamANXA5
Homologs : HomoloGeneANXA5
Homology/Alignments : Family Browser (UCSC)ANXA5
Gene fusions - Rearrangements
Fusion : QuiverANXA5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANXA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANXA5
dbVarANXA5
ClinVarANXA5
MonarchANXA5
1000_GenomesANXA5 
Exome Variant ServerANXA5
GNOMAD BrowserENSG00000164111
Varsome BrowserANXA5
ACMGANXA5 variants
VarityP08758
Genomic Variants (DGV)ANXA5 [DGVbeta]
DECIPHERANXA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANXA5 
Mutations
ICGC Data PortalANXA5 
TCGA Data PortalANXA5 
Broad Tumor PortalANXA5
OASIS PortalANXA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANXA5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANXA5
Mutations and Diseases : HGMDANXA5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANXA5
DgiDB (Drug Gene Interaction Database)ANXA5
DoCM (Curated mutations)ANXA5
CIViC (Clinical Interpretations of Variants in Cancer)ANXA5
Cancer3DANXA5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM131230    614391   
Orphanet
DisGeNETANXA5
MedgenANXA5
Genetic Testing Registry ANXA5
NextProtP08758 [Medical]
GENETestsANXA5
Target ValidationANXA5
Huge Navigator ANXA5 [HugePedia]
ClinGenANXA5
Clinical trials, drugs, therapy
MyCancerGenomeANXA5
Protein Interactions : CTDANXA5
Pharm GKB GenePA24833
PharosP08758
Clinical trialANXA5
Miscellaneous
canSAR (ICR)ANXA5
HarmonizomeANXA5
ARCHS4ANXA5
DataMed IndexANXA5
Probes
Litterature
PubMed273 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANXA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 20 12:22:37 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.