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ANXA8 (annexin A8)

Identity

Alias (NCBI)ANX8
CH17-360D5.2
HGNC (Hugo) ANXA8
HGNC Previous nameANX8
LocusID (NCBI) 653145
Atlas_Id 50053
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 47467994 and ends at 47484158 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANXA8 (10q11.22) / EPG5 (18q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)ANXA8   546
Cards
Entrez_Gene (NCBI)ANXA8    annexin A8
AliasesANX8; CH17-360D5.2
GeneCards (Weizmann)ANXA8
Ensembl hg19 (Hinxton)ENSG00000265190 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000265190 [Gene_View]  ENSG00000265190 [Sequence]  chr10:47467994-47484158 [Contig_View]  ANXA8 [Vega]
ICGC DataPortalENSG00000265190
TCGA cBioPortalANXA8
AceView (NCBI)ANXA8
Genatlas (Paris)ANXA8
SOURCE (Princeton)ANXA8
Genetics Home Reference (NIH)ANXA8
Genomic and cartography
GoldenPath hg38 (UCSC)ANXA8  -     chr10:47467994-47484158 -  10q11.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ANXA8  -     10q11.22   [Description]    (hg19-Feb_2009)
GoldenPathANXA8 - 10q11.22 [CytoView hg19]  ANXA8 - 10q11.22 [CytoView hg38]
ImmunoBaseENSG00000265190
Genome Data Viewer NCBIANXA8 [Mapview hg19]  
OMIM602396   
Gene and transcription
Genbank (Entrez)AK296573 AK296976 AK298761 AK300139 AK300158
RefSeq transcript (Entrez)NM_001040084 NM_001271702 NM_001271703
Consensus coding sequences : CCDS (NCBI)ANXA8
Gene ExpressionANXA8 [ NCBI-GEO ]   ANXA8 [ EBI - ARRAY_EXPRESS ]   ANXA8 [ SEEK ]   ANXA8 [ MEM ]
Gene Expression Viewer (FireBrowse)ANXA8 [ Firebrowse - Broad ]
GenevisibleExpression of ANXA8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)653145
GTEX Portal (Tissue expression)ANXA8
Human Protein AtlasENSG00000265190-ANXA8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP13928   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP13928  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP13928
PhosPhoSitePlusP13928
Domaine pattern : Prosite (Expaxy)ANNEXIN_1 (PS00223)    ANNEXIN_2 (PS51897)   
Domains : Interpro (EBI)Annexin    Annexin_repeat    Annexin_repeat_CS    Annexin_sf    ANX8   
Domain families : Pfam (Sanger)Annexin (PF00191)   
Domain families : Pfam (NCBI)pfam00191   
Domain families : Smart (EMBL)ANX (SM00335)  
Conserved Domain (NCBI)ANXA8
PDB (RSDB)1W3W    1W45   
PDB Europe1W3W    1W45   
PDB (PDBSum)1W3W    1W45   
PDB (IMB)1W3W    1W45   
Structural Biology KnowledgeBase1W3W    1W45   
SCOP (Structural Classification of Proteins)1W3W    1W45   
CATH (Classification of proteins structures)1W3W    1W45   
SuperfamilyP13928
AlphaFold pdb e-kbP13928   
Human Protein Atlas [tissue]ENSG00000265190-ANXA8 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P13928
IntAct (EBI)P13928
BioGRIDANXA8
STRING (EMBL)ANXA8
ZODIACANXA8
Ontologies - Pathways
QuickGOP13928
Ontology : AmiGOcalcium ion binding  calcium ion binding  protein binding  calcium-dependent phospholipid binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  cytoplasm  cytosol  plasma membrane  endosome organization  endosome organization  blood coagulation  endosomal transport  endosomal transport  late endosome membrane  phosphatidylinositol-3,4-bisphosphate binding  actin filament binding  collagen-containing extracellular matrix  negative regulation of serine-type endopeptidase activity  negative regulation of serine-type endopeptidase activity  negative regulation of phospholipase A2 activity  negative regulation of phospholipase A2 activity  
Ontology : EGO-EBIcalcium ion binding  calcium ion binding  protein binding  calcium-dependent phospholipid binding  phosphatidylinositol-4,5-bisphosphate binding  phosphatidylinositol-3,4,5-trisphosphate binding  cytoplasm  cytosol  plasma membrane  endosome organization  endosome organization  blood coagulation  endosomal transport  endosomal transport  late endosome membrane  phosphatidylinositol-3,4-bisphosphate binding  actin filament binding  collagen-containing extracellular matrix  negative regulation of serine-type endopeptidase activity  negative regulation of serine-type endopeptidase activity  negative regulation of phospholipase A2 activity  negative regulation of phospholipase A2 activity  
NDEx NetworkANXA8
Atlas of Cancer Signalling NetworkANXA8
Wikipedia pathwaysANXA8
Orthology - Evolution
OrthoDB653145
GeneTree (enSembl)ENSG00000265190
Phylogenetic Trees/Animal Genes : TreeFamANXA8
Homologs : HomoloGeneANXA8
Homology/Alignments : Family Browser (UCSC)ANXA8
Gene fusions - Rearrangements
Fusion : QuiverANXA8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerANXA8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ANXA8
dbVarANXA8
ClinVarANXA8
MonarchANXA8
1000_GenomesANXA8 
Exome Variant ServerANXA8
GNOMAD BrowserENSG00000265190
Varsome BrowserANXA8
ACMGANXA8 variants
VarityP13928
Genomic Variants (DGV)ANXA8 [DGVbeta]
DECIPHERANXA8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisANXA8 
Mutations
ICGC Data PortalANXA8 
TCGA Data PortalANXA8 
Broad Tumor PortalANXA8
OASIS PortalANXA8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICANXA8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DANXA8
Mutations and Diseases : HGMDANXA8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaANXA8
DgiDB (Drug Gene Interaction Database)ANXA8
DoCM (Curated mutations)ANXA8
CIViC (Clinical Interpretations of Variants in Cancer)ANXA8
Cancer3DANXA8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602396   
Orphanet
DisGeNETANXA8
MedgenANXA8
Genetic Testing Registry ANXA8
NextProtP13928 [Medical]
GENETestsANXA8
Target ValidationANXA8
Huge Navigator ANXA8 [HugePedia]
ClinGenANXA8
Clinical trials, drugs, therapy
MyCancerGenomeANXA8
Protein Interactions : CTDANXA8
Pharm GKB GenePA24836
PharosP13928
Clinical trialANXA8
Miscellaneous
canSAR (ICR)ANXA8
HarmonizomeANXA8
DataMed IndexANXA8
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXANXA8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 14:59:33 CEST 2021

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