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AOC1 (amine oxidase, copper containing 1)

Identity

Alias_namesABP1
amiloride binding protein 1 (amine oxidase (copper-containing))
Alias_symbol (synonym)DAO
Other aliasABP
DAO1
KAO
HGNC (Hugo) AOC1
LocusID (NCBI) 26
Atlas_Id 53470
Location 7q36.1  [Link to chromosome band 7q36]
Location_base_pair Starts at 150852477 and ends at 150861291 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AOC1   80
Cards
Entrez_Gene (NCBI)AOC1  26  amine oxidase, copper containing 1
AliasesABP; ABP1; DAO; DAO1; 
KAO
GeneCards (Weizmann)AOC1
Ensembl hg19 (Hinxton)ENSG00000002726 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000002726 [Gene_View]  chr7:150852477-150861291 [Contig_View]  AOC1 [Vega]
ICGC DataPortalENSG00000002726
TCGA cBioPortalAOC1
AceView (NCBI)AOC1
Genatlas (Paris)AOC1
WikiGenes26
SOURCE (Princeton)AOC1
Genetics Home Reference (NIH)AOC1
Genomic and cartography
GoldenPath hg38 (UCSC)AOC1  -     chr7:150852477-150861291 +  7q36.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AOC1  -     7q36.1   [Description]    (hg19-Feb_2009)
EnsemblAOC1 - 7q36.1 [CytoView hg19]  AOC1 - 7q36.1 [CytoView hg38]
Mapping of homologs : NCBIAOC1 [Mapview hg19]  AOC1 [Mapview hg38]
OMIM104610   
Gene and transcription
Genbank (Entrez)AK092514 AK296638 AK307278 AK314806 BC014093
RefSeq transcript (Entrez)NM_001091 NM_001272072
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AOC1
Cluster EST : UnigeneHs.733889 [ NCBI ]
CGAP (NCI)Hs.733889
Alternative Splicing GalleryENSG00000002726
Gene ExpressionAOC1 [ NCBI-GEO ]   AOC1 [ EBI - ARRAY_EXPRESS ]   AOC1 [ SEEK ]   AOC1 [ MEM ]
Gene Expression Viewer (FireBrowse)AOC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26
GTEX Portal (Tissue expression)AOC1
Human Protein AtlasENSG00000002726-AOC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19801   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP19801  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19801
Splice isoforms : SwissVarP19801
PhosPhoSitePlusP19801
Domaine pattern : Prosite (Expaxy)COPPER_AMINE_OXID_1 (PS01164)    COPPER_AMINE_OXID_2 (PS01165)   
Domains : Interpro (EBI)Cu_amine_oxidase    Cu_amine_oxidase_C    Cu_amine_oxidase_N-reg    Cu_amine_oxidase_N2    Cu_amine_oxidase_N3   
Domain families : Pfam (Sanger)Cu_amine_oxid (PF01179)    Cu_amine_oxidN2 (PF02727)    Cu_amine_oxidN3 (PF02728)   
Domain families : Pfam (NCBI)pfam01179    pfam02727    pfam02728   
Conserved Domain (NCBI)AOC1
DMDM Disease mutations26
Blocks (Seattle)AOC1
PDB (SRS)3HI7    3HIG    3HII    3K5T    3MPH   
PDB (PDBSum)3HI7    3HIG    3HII    3K5T    3MPH   
PDB (IMB)3HI7    3HIG    3HII    3K5T    3MPH   
PDB (RSDB)3HI7    3HIG    3HII    3K5T    3MPH   
Structural Biology KnowledgeBase3HI7    3HIG    3HII    3K5T    3MPH   
SCOP (Structural Classification of Proteins)3HI7    3HIG    3HII    3K5T    3MPH   
CATH (Classification of proteins structures)3HI7    3HIG    3HII    3K5T    3MPH   
SuperfamilyP19801
Human Protein Atlas [tissue]ENSG00000002726-AOC1 [tissue]
Peptide AtlasP19801
HPRD00088
IPIIPI00020982   IPI00219832   IPI00908979   IPI00956005   IPI01009159   IPI00783534   IPI00953666   IPI00947111   
Protein Interaction databases
DIP (DOE-UCLA)P19801
IntAct (EBI)P19801
FunCoupENSG00000002726
BioGRIDAOC1
STRING (EMBL)AOC1
ZODIACAOC1
Ontologies - Pathways
QuickGOP19801
Ontology : AmiGOreceptor activity  copper ion binding  calcium ion binding  extracellular region  extracellular space  peroxisome  plasma membrane  plasma membrane  bicellular tight junction  xenobiotic metabolic process  primary amine oxidase activity  drug binding  heparin binding  zinc ion binding  amine metabolic process  protein complex binding  specific granule lumen  cellular response to copper ion starvation  response to drug  protein homodimerization activity  neutrophil degranulation  response to antibiotic  quinone binding  diamine oxidase activity  histamine oxidase activity  methylputrescine oxidase activity  propane-1,3-diamine oxidase activity  oxidation-reduction process  extracellular exosome  cellular response to copper ion  cellular response to histamine  cellular response to heparin  cellular response to azide  
Ontology : EGO-EBIreceptor activity  copper ion binding  calcium ion binding  extracellular region  extracellular space  peroxisome  plasma membrane  plasma membrane  bicellular tight junction  xenobiotic metabolic process  primary amine oxidase activity  drug binding  heparin binding  zinc ion binding  amine metabolic process  protein complex binding  specific granule lumen  cellular response to copper ion starvation  response to drug  protein homodimerization activity  neutrophil degranulation  response to antibiotic  quinone binding  diamine oxidase activity  histamine oxidase activity  methylputrescine oxidase activity  propane-1,3-diamine oxidase activity  oxidation-reduction process  extracellular exosome  cellular response to copper ion  cellular response to histamine  cellular response to heparin  cellular response to azide  
Pathways : KEGGArginine and proline metabolism    Histidine metabolism    Tryptophan metabolism   
NDEx NetworkAOC1
Atlas of Cancer Signalling NetworkAOC1
Wikipedia pathwaysAOC1
Orthology - Evolution
OrthoDB26
GeneTree (enSembl)ENSG00000002726
Phylogenetic Trees/Animal Genes : TreeFamAOC1
HOVERGENP19801
HOGENOMP19801
Homologs : HomoloGeneAOC1
Homology/Alignments : Family Browser (UCSC)AOC1
Gene fusions - Rearrangements
Tumor Fusion PortalAOC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAOC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AOC1
dbVarAOC1
ClinVarAOC1
1000_GenomesAOC1 
Exome Variant ServerAOC1
ExAC (Exome Aggregation Consortium)ENSG00000002726
GNOMAD BrowserENSG00000002726
Genetic variants : HAPMAP26
Genomic Variants (DGV)AOC1 [DGVbeta]
DECIPHERAOC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAOC1 
Mutations
ICGC Data PortalAOC1 
TCGA Data PortalAOC1 
Broad Tumor PortalAOC1
OASIS PortalAOC1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDAOC1
BioMutasearch AOC1
DgiDB (Drug Gene Interaction Database)AOC1
DoCM (Curated mutations)AOC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AOC1 (select a term)
intoGenAOC1
Cancer3DAOC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104610   
Orphanet
DisGeNETAOC1
MedgenAOC1
Genetic Testing Registry AOC1
NextProtP19801 [Medical]
TSGene26
GENETestsAOC1
Target ValidationAOC1
Huge Navigator AOC1 [HugePedia]
snp3D : Map Gene to Disease26
BioCentury BCIQAOC1
ClinGenAOC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26
Chemical/Pharm GKB GenePA24416
Clinical trialAOC1
Miscellaneous
canSAR (ICR)AOC1 (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAOC1
EVEXAOC1
GoPubMedAOC1
iHOPAOC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:11 CET 2017

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