Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AOC2 (amine oxidase, copper containing 2)

Identity

Alias_namesamine oxidase, copper containing 2 (retina-specific)
Alias_symbol (synonym)RAO
DAO2
Other aliasSSAO
HGNC (Hugo) AOC2
LocusID (NCBI) 314
Atlas_Id 60392
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 42844583 and ends at 42850712 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AOC2   549
Cards
Entrez_Gene (NCBI)AOC2  314  amine oxidase, copper containing 2
AliasesDAO2; RAO; SSAO
GeneCards (Weizmann)AOC2
Ensembl hg19 (Hinxton)ENSG00000131480 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131480 [Gene_View]  chr17:42844583-42850712 [Contig_View]  AOC2 [Vega]
ICGC DataPortalENSG00000131480
TCGA cBioPortalAOC2
AceView (NCBI)AOC2
Genatlas (Paris)AOC2
WikiGenes314
SOURCE (Princeton)AOC2
Genetics Home Reference (NIH)AOC2
Genomic and cartography
GoldenPath hg38 (UCSC)AOC2  -     chr17:42844583-42850712 +  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AOC2  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblAOC2 - 17q21.31 [CytoView hg19]  AOC2 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIAOC2 [Mapview hg19]  AOC2 [Mapview hg38]
OMIM602268   
Gene and transcription
Genbank (Entrez)AF081363 BC142641 CA425343 CA427935 CN355968
RefSeq transcript (Entrez)NM_001158 NM_009590
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AOC2
Cluster EST : UnigeneHs.143102 [ NCBI ]
CGAP (NCI)Hs.143102
Alternative Splicing GalleryENSG00000131480
Gene ExpressionAOC2 [ NCBI-GEO ]   AOC2 [ EBI - ARRAY_EXPRESS ]   AOC2 [ SEEK ]   AOC2 [ MEM ]
Gene Expression Viewer (FireBrowse)AOC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)314
GTEX Portal (Tissue expression)AOC2
Human Protein AtlasENSG00000131480-AOC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75106   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75106  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75106
Splice isoforms : SwissVarO75106
PhosPhoSitePlusO75106
Domaine pattern : Prosite (Expaxy)COPPER_AMINE_OXID_1 (PS01164)    COPPER_AMINE_OXID_2 (PS01165)   
Domains : Interpro (EBI)AOC2    Cu_amine_oxidase    Cu_amine_oxidase_C    Cu_amine_oxidase_N-reg    Cu_amine_oxidase_N2    Cu_amine_oxidase_N3   
Domain families : Pfam (Sanger)Cu_amine_oxid (PF01179)    Cu_amine_oxidN2 (PF02727)    Cu_amine_oxidN3 (PF02728)   
Domain families : Pfam (NCBI)pfam01179    pfam02727    pfam02728   
Conserved Domain (NCBI)AOC2
DMDM Disease mutations314
Blocks (Seattle)AOC2
SuperfamilyO75106
Human Protein Atlas [tissue]ENSG00000131480-AOC2 [tissue]
Peptide AtlasO75106
HPRD11889
IPIIPI00024357   IPI00293889   
Protein Interaction databases
DIP (DOE-UCLA)O75106
IntAct (EBI)O75106
FunCoupENSG00000131480
BioGRIDAOC2
STRING (EMBL)AOC2
ZODIACAOC2
Ontologies - Pathways
QuickGOO75106
Ontology : AmiGOcopper ion binding  cytoplasm  plasma membrane  catecholamine metabolic process  xenobiotic metabolic process  visual perception  primary amine oxidase activity  electron carrier activity  amine metabolic process  quinone binding  tryptamine:oxygen oxidoreductase (deaminating) activity  aminoacetone:oxygen oxidoreductase(deaminating) activity  aliphatic-amine oxidase activity  phenethylamine:oxygen oxidoreductase (deaminating) activity  oxidation-reduction process  
Ontology : EGO-EBIcopper ion binding  cytoplasm  plasma membrane  catecholamine metabolic process  xenobiotic metabolic process  visual perception  primary amine oxidase activity  electron carrier activity  amine metabolic process  quinone binding  tryptamine:oxygen oxidoreductase (deaminating) activity  aminoacetone:oxygen oxidoreductase(deaminating) activity  aliphatic-amine oxidase activity  phenethylamine:oxygen oxidoreductase (deaminating) activity  oxidation-reduction process  
Pathways : KEGGGlycine, serine and threonine metabolism    Tyrosine metabolism    Phenylalanine metabolism    beta-Alanine metabolism   
NDEx NetworkAOC2
Atlas of Cancer Signalling NetworkAOC2
Wikipedia pathwaysAOC2
Orthology - Evolution
OrthoDB314
GeneTree (enSembl)ENSG00000131480
Phylogenetic Trees/Animal Genes : TreeFamAOC2
HOVERGENO75106
HOGENOMO75106
Homologs : HomoloGeneAOC2
Homology/Alignments : Family Browser (UCSC)AOC2
Gene fusions - Rearrangements
Tumor Fusion PortalAOC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAOC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AOC2
dbVarAOC2
ClinVarAOC2
1000_GenomesAOC2 
Exome Variant ServerAOC2
ExAC (Exome Aggregation Consortium)ENSG00000131480
GNOMAD BrowserENSG00000131480
Genetic variants : HAPMAP314
Genomic Variants (DGV)AOC2 [DGVbeta]
DECIPHERAOC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAOC2 
Mutations
ICGC Data PortalAOC2 
TCGA Data PortalAOC2 
Broad Tumor PortalAOC2
OASIS PortalAOC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAOC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAOC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AOC2
DgiDB (Drug Gene Interaction Database)AOC2
DoCM (Curated mutations)AOC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AOC2 (select a term)
intoGenAOC2
Cancer3DAOC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602268   
Orphanet
DisGeNETAOC2
MedgenAOC2
Genetic Testing Registry AOC2
NextProtO75106 [Medical]
TSGene314
GENETestsAOC2
Target ValidationAOC2
Huge Navigator AOC2 [HugePedia]
snp3D : Map Gene to Disease314
BioCentury BCIQAOC2
ClinGenAOC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD314
Chemical/Pharm GKB GenePA24839
Clinical trialAOC2
Miscellaneous
canSAR (ICR)AOC2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAOC2
EVEXAOC2
GoPubMedAOC2
iHOPAOC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Nov 20 19:18:50 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.