Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AOC3 (amine oxidase, copper containing 3)

Identity

Alias_symbol (synonym)VAP1
HPAO
VAP-1
Other aliasSSAO
HGNC (Hugo) AOC3
LocusID (NCBI) 8639
Atlas_Id 45604
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 42851184 and ends at 42858131 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AOC3   550
Cards
Entrez_Gene (NCBI)AOC3  8639  amine oxidase, copper containing 3
AliasesHPAO; SSAO; VAP-1; VAP1
GeneCards (Weizmann)AOC3
Ensembl hg19 (Hinxton)ENSG00000131471 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131471 [Gene_View]  chr17:42851184-42858131 [Contig_View]  AOC3 [Vega]
ICGC DataPortalENSG00000131471
TCGA cBioPortalAOC3
AceView (NCBI)AOC3
Genatlas (Paris)AOC3
WikiGenes8639
SOURCE (Princeton)AOC3
Genetics Home Reference (NIH)AOC3
Genomic and cartography
GoldenPath hg38 (UCSC)AOC3  -     chr17:42851184-42858131 +  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AOC3  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblAOC3 - 17q21.31 [CytoView hg19]  AOC3 - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBIAOC3 [Mapview hg19]  AOC3 [Mapview hg38]
OMIM603735   
Gene and transcription
Genbank (Entrez)AF054985 AF067406 AK025727 AK315129 BC036368
RefSeq transcript (Entrez)NM_001277731 NM_001277732 NM_003734
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AOC3
Cluster EST : UnigeneHs.198241 [ NCBI ]
CGAP (NCI)Hs.198241
Alternative Splicing GalleryENSG00000131471
Gene ExpressionAOC3 [ NCBI-GEO ]   AOC3 [ EBI - ARRAY_EXPRESS ]   AOC3 [ SEEK ]   AOC3 [ MEM ]
Gene Expression Viewer (FireBrowse)AOC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8639
GTEX Portal (Tissue expression)AOC3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16853   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16853  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16853
Splice isoforms : SwissVarQ16853
PhosPhoSitePlusQ16853
Domaine pattern : Prosite (Expaxy)COPPER_AMINE_OXID_1 (PS01164)    COPPER_AMINE_OXID_2 (PS01165)   
Domains : Interpro (EBI)Cu_amine_oxidase    Cu_amine_oxidase_C    Cu_amine_oxidase_N-reg    Cu_amine_oxidase_N2    Cu_amine_oxidase_N3   
Domain families : Pfam (Sanger)Cu_amine_oxid (PF01179)    Cu_amine_oxidN2 (PF02727)    Cu_amine_oxidN3 (PF02728)   
Domain families : Pfam (NCBI)pfam01179    pfam02727    pfam02728   
Conserved Domain (NCBI)AOC3
DMDM Disease mutations8639
Blocks (Seattle)AOC3
PDB (SRS)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
PDB (PDBSum)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
PDB (IMB)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
PDB (RSDB)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
Structural Biology KnowledgeBase1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
SCOP (Structural Classification of Proteins)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
CATH (Classification of proteins structures)1PU4    1US1    2C10    2C11    2Y73    2Y74    3ALA    4BTW    4BTX    4BTY   
SuperfamilyQ16853
Human Protein AtlasENSG00000131471
Peptide AtlasQ16853
HPRD04770
IPIIPI00004457   
Protein Interaction databases
DIP (DOE-UCLA)Q16853
IntAct (EBI)Q16853
FunCoupENSG00000131471
BioGRIDAOC3
STRING (EMBL)AOC3
ZODIACAOC3
Ontologies - Pathways
QuickGOQ16853
Ontology : AmiGOcopper ion binding  calcium ion binding  protein binding  cytoplasm  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  plasma membrane  microvillus  xenobiotic metabolic process  inflammatory response  cell adhesion  primary amine oxidase activity  primary amine oxidase activity  primary amine oxidase activity  amine metabolic process  cell surface  integral component of membrane  protein homodimerization activity  response to antibiotic  protein heterodimerization activity  quinone binding  tryptamine:oxygen oxidoreductase (deaminating) activity  aminoacetone:oxygen oxidoreductase(deaminating) activity  aliphatic-amine oxidase activity  phenethylamine:oxygen oxidoreductase (deaminating) activity  oxidation-reduction process  negative regulation of primary amine oxidase activity  
Ontology : EGO-EBIcopper ion binding  calcium ion binding  protein binding  cytoplasm  early endosome  endoplasmic reticulum  Golgi apparatus  plasma membrane  plasma membrane  microvillus  xenobiotic metabolic process  inflammatory response  cell adhesion  primary amine oxidase activity  primary amine oxidase activity  primary amine oxidase activity  amine metabolic process  cell surface  integral component of membrane  protein homodimerization activity  response to antibiotic  protein heterodimerization activity  quinone binding  tryptamine:oxygen oxidoreductase (deaminating) activity  aminoacetone:oxygen oxidoreductase(deaminating) activity  aliphatic-amine oxidase activity  phenethylamine:oxygen oxidoreductase (deaminating) activity  oxidation-reduction process  negative regulation of primary amine oxidase activity  
Pathways : KEGGGlycine, serine and threonine metabolism    Tyrosine metabolism    Phenylalanine metabolism    beta-Alanine metabolism   
NDEx NetworkAOC3
Atlas of Cancer Signalling NetworkAOC3
Wikipedia pathwaysAOC3
Orthology - Evolution
OrthoDB8639
GeneTree (enSembl)ENSG00000131471
Phylogenetic Trees/Animal Genes : TreeFamAOC3
HOVERGENQ16853
HOGENOMQ16853
Homologs : HomoloGeneAOC3
Homology/Alignments : Family Browser (UCSC)AOC3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAOC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AOC3
dbVarAOC3
ClinVarAOC3
1000_GenomesAOC3 
Exome Variant ServerAOC3
ExAC (Exome Aggregation Consortium)AOC3 (select the gene name)
Genetic variants : HAPMAP8639
Genomic Variants (DGV)AOC3 [DGVbeta]
DECIPHERAOC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAOC3 
Mutations
ICGC Data PortalAOC3 
TCGA Data PortalAOC3 
Broad Tumor PortalAOC3
OASIS PortalAOC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAOC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAOC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AOC3
DgiDB (Drug Gene Interaction Database)AOC3
DoCM (Curated mutations)AOC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AOC3 (select a term)
intoGenAOC3
Cancer3DAOC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603735   
Orphanet
MedgenAOC3
Genetic Testing Registry AOC3
NextProtQ16853 [Medical]
TSGene8639
GENETestsAOC3
Huge Navigator AOC3 [HugePedia]
snp3D : Map Gene to Disease8639
BioCentury BCIQAOC3
ClinGenAOC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8639
Chemical/Pharm GKB GenePA24840
Clinical trialAOC3
Miscellaneous
canSAR (ICR)AOC3 (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAOC3
EVEXAOC3
GoPubMedAOC3
iHOPAOC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:06:09 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.