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AOPEP (chromosome 9 open reading frame 3)

Identity

Other aliasAOPEP
AP-O
APO
C90RF3
ONPEP
HGNC (Hugo) AOPEP
LocusID (NCBI) 84909
Atlas_Id 57065
Location 9q22.32  [Link to chromosome band 9q22]
Location_base_pair Starts at 94726669 and ends at 95087218 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  C9orf3/PTPDC1 (9q22)
FANCC/C9orf3 (9q22)
t(9;12)(q22;q15) CPSF6/C9orf3


External links

Nomenclature
HGNC (Hugo)AOPEP   1361
Cards
Entrez_Gene (NCBI)AOPEP  84909  chromosome 9 open reading frame 3
AliasesAOPEP; AP-O; APO; C90RF3; 
ONPEP
GeneCards (Weizmann)AOPEP
Ensembl hg19 (Hinxton)ENSG00000148120 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148120 [Gene_View]  ENSG00000148120 [Sequence]  chr9:94726669-95087218 [Contig_View]  AOPEP [Vega]
ICGC DataPortalENSG00000148120
TCGA cBioPortalAOPEP
AceView (NCBI)AOPEP
Genatlas (Paris)AOPEP
WikiGenes84909
SOURCE (Princeton)AOPEP
Genetics Home Reference (NIH)AOPEP
Genomic and cartography
GoldenPath hg38 (UCSC)AOPEP  -     chr9:94726669-95087218 +  9q22.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AOPEP  -     9q22.32   [Description]    (hg19-Feb_2009)
GoldenPathAOPEP - 9q22.32 [CytoView hg19]  AOPEP - 9q22.32 [CytoView hg38]
ImmunoBaseENSG00000148120
Mapping of homologs : NCBIAOPEP [Mapview hg19]  AOPEP [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF043896 AF043897 AI982632 AJ560639 AK027581
RefSeq transcript (Entrez)NM_001193329 NM_001193330 NM_001193331 NM_032823
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AOPEP
Cluster EST : UnigeneHs.675327 [ NCBI ]
CGAP (NCI)Hs.675327
Alternative Splicing GalleryENSG00000148120
Gene ExpressionAOPEP [ NCBI-GEO ]   AOPEP [ EBI - ARRAY_EXPRESS ]   AOPEP [ SEEK ]   AOPEP [ MEM ]
Gene Expression Viewer (FireBrowse)AOPEP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84909
GTEX Portal (Tissue expression)AOPEP
Human Protein AtlasENSG00000148120-AOPEP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N6M6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N6M6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N6M6
Splice isoforms : SwissVarQ8N6M6
PhosPhoSitePlusQ8N6M6
Domains : Interpro (EBI)AOPep    ARM-type_fold    M1_LTA-4_hydro/amino_C_sf    Peptidase_M1    Peptidase_M1_C    Peptidase_M1_N   
Domain families : Pfam (Sanger)Leuk-A4-hydro_C (PF09127)    Peptidase_M1 (PF01433)   
Domain families : Pfam (NCBI)pfam09127    pfam01433   
Domain families : Smart (EMBL)Leuk-A4-hydro_C (SM01263)  
Conserved Domain (NCBI)AOPEP
DMDM Disease mutations84909
Blocks (Seattle)AOPEP
SuperfamilyQ8N6M6
Human Protein Atlas [tissue]ENSG00000148120-AOPEP [tissue]
Peptide AtlasQ8N6M6
IPIIPI00163493   IPI00171144   IPI00554492   IPI00647187   IPI00909505   IPI00908509   IPI00552364   IPI00187032   IPI00552746   IPI00978523   
Protein Interaction databases
DIP (DOE-UCLA)Q8N6M6
IntAct (EBI)Q8N6M6
FunCoupENSG00000148120
BioGRIDAOPEP
STRING (EMBL)AOPEP
ZODIACAOPEP
Ontologies - Pathways
QuickGOQ8N6M6
Ontology : AmiGOangiotensin maturation  aminopeptidase activity  aminopeptidase activity  aminopeptidase activity  nucleolus  cytosol  proteolysis  metallopeptidase activity  metallopeptidase activity  zinc ion binding  metalloaminopeptidase activity  
Ontology : EGO-EBIangiotensin maturation  aminopeptidase activity  aminopeptidase activity  aminopeptidase activity  nucleolus  cytosol  proteolysis  metallopeptidase activity  metallopeptidase activity  zinc ion binding  metalloaminopeptidase activity  
NDEx NetworkAOPEP
Atlas of Cancer Signalling NetworkAOPEP
Wikipedia pathwaysAOPEP
Orthology - Evolution
OrthoDB84909
GeneTree (enSembl)ENSG00000148120
Phylogenetic Trees/Animal Genes : TreeFamAOPEP
HOGENOMQ8N6M6
Homologs : HomoloGeneAOPEP
Homology/Alignments : Family Browser (UCSC)AOPEP
Gene fusions - Rearrangements
Fusion : QuiverAOPEP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAOPEP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AOPEP
dbVarAOPEP
ClinVarAOPEP
1000_GenomesAOPEP 
Exome Variant ServerAOPEP
ExAC (Exome Aggregation Consortium)ENSG00000148120
GNOMAD BrowserENSG00000148120
Varsome BrowserAOPEP
Genetic variants : HAPMAP84909
Genomic Variants (DGV)AOPEP [DGVbeta]
DECIPHERAOPEP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAOPEP 
Mutations
ICGC Data PortalAOPEP 
TCGA Data PortalAOPEP 
Broad Tumor PortalAOPEP
OASIS PortalAOPEP [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDAOPEP
BioMutasearch AOPEP
DgiDB (Drug Gene Interaction Database)AOPEP
DoCM (Curated mutations)AOPEP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AOPEP (select a term)
intoGenAOPEP
Cancer3DAOPEP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETAOPEP
MedgenAOPEP
Genetic Testing Registry AOPEP
NextProtQ8N6M6 [Medical]
TSGene84909
GENETestsAOPEP
Target ValidationAOPEP
Huge Navigator AOPEP [HugePedia]
snp3D : Map Gene to Disease84909
BioCentury BCIQAOPEP
ClinGenAOPEP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84909
Chemical/Pharm GKB GenePA25978
Clinical trialAOPEP
Miscellaneous
canSAR (ICR)AOPEP (select the gene name)
DataMed IndexAOPEP
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAOPEP
EVEXAOPEP
GoPubMedAOPEP
iHOPAOPEP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 8 11:10:41 CEST 2019

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