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AP1AR (adaptor-related protein complex 1 associated regulatory protein)

Identity

Alias_namesC4orf16
chromosome 4 open reading frame 16
adaptor-related protein complex 1 associated regulatory protein
Alias_symbol (synonym)PRO0971
2C18
gamma-BAR
Other aliasGBAR
HGNC (Hugo) AP1AR
LocusID (NCBI) 55435
Atlas_Id 60395
Location 4q25  [Link to chromosome band 4q25]
Location_base_pair Starts at 113152895 and ends at 113191211 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AP1AR (4q25) / NDST4 (4q26)AP1AR (4q25) / SRSF7 (2p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP1AR   28808
Cards
Entrez_Gene (NCBI)AP1AR  55435  adaptor-related protein complex 1 associated regulatory protein
Aliases2C18; C4orf16; GBAR; PRO0971; 
gamma-BAR
GeneCards (Weizmann)AP1AR
Ensembl hg19 (Hinxton)ENSG00000138660 [Gene_View]  chr4:113152895-113191211 [Contig_View]  AP1AR [Vega]
Ensembl hg38 (Hinxton)ENSG00000138660 [Gene_View]  chr4:113152895-113191211 [Contig_View]  AP1AR [Vega]
ICGC DataPortalENSG00000138660
TCGA cBioPortalAP1AR
AceView (NCBI)AP1AR
Genatlas (Paris)AP1AR
WikiGenes55435
SOURCE (Princeton)AP1AR
Genetics Home Reference (NIH)AP1AR
Genomic and cartography
GoldenPath hg19 (UCSC)AP1AR  -     chr4:113152895-113191211 +  4q25   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AP1AR  -     4q25   [Description]    (hg38-Dec_2013)
EnsemblAP1AR - 4q25 [CytoView hg19]  AP1AR - 4q25 [CytoView hg38]
Mapping of homologs : NCBIAP1AR [Mapview hg19]  AP1AR [Mapview hg38]
OMIM610851   
Gene and transcription
Genbank (Entrez)AF116612 AI273122 AK310787 AK315299 AL136628
RefSeq transcript (Entrez)NM_001128426 NM_018569
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)AP1AR
Cluster EST : UnigeneHs.606210 [ NCBI ]
CGAP (NCI)Hs.606210
Alternative Splicing GalleryENSG00000138660
Gene ExpressionAP1AR [ NCBI-GEO ]   AP1AR [ EBI - ARRAY_EXPRESS ]   AP1AR [ SEEK ]   AP1AR [ MEM ]
Gene Expression Viewer (FireBrowse)AP1AR [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55435
GTEX Portal (Tissue expression)AP1AR
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ63HQ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ63HQ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ63HQ0
Splice isoforms : SwissVarQ63HQ0
PhosPhoSitePlusQ63HQ0
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)AP1AR
DMDM Disease mutations55435
Blocks (Seattle)AP1AR
SuperfamilyQ63HQ0
Human Protein AtlasENSG00000138660
Peptide AtlasQ63HQ0
HPRD12824
IPIIPI00000795   IPI00305539   IPI00964614   
Protein Interaction databases
DIP (DOE-UCLA)Q63HQ0
IntAct (EBI)Q63HQ0
FunCoupENSG00000138660
BioGRIDAP1AR
STRING (EMBL)AP1AR
ZODIACAP1AR
Ontologies - Pathways
QuickGOQ63HQ0
Ontology : AmiGOnegative regulation of receptor recycling  early endosome  late endosome  Golgi apparatus  protein transport  kinesin binding  transport vesicle  regulation of Arp2/3 complex-mediated actin nucleation  cellular protein localization  AP-1 adaptor complex binding  vesicle targeting, trans-Golgi to endosome  negative regulation of substrate adhesion-dependent cell spreading  negative regulation of cell motility  
Ontology : EGO-EBInegative regulation of receptor recycling  early endosome  late endosome  Golgi apparatus  protein transport  kinesin binding  transport vesicle  regulation of Arp2/3 complex-mediated actin nucleation  cellular protein localization  AP-1 adaptor complex binding  vesicle targeting, trans-Golgi to endosome  negative regulation of substrate adhesion-dependent cell spreading  negative regulation of cell motility  
NDEx NetworkAP1AR
Atlas of Cancer Signalling NetworkAP1AR
Wikipedia pathwaysAP1AR
Orthology - Evolution
OrthoDB55435
GeneTree (enSembl)ENSG00000138660
Phylogenetic Trees/Animal Genes : TreeFamAP1AR
HOVERGENQ63HQ0
HOGENOMQ63HQ0
Homologs : HomoloGeneAP1AR
Homology/Alignments : Family Browser (UCSC)AP1AR
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1AR [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1AR
dbVarAP1AR
ClinVarAP1AR
1000_GenomesAP1AR 
Exome Variant ServerAP1AR
ExAC (Exome Aggregation Consortium)AP1AR (select the gene name)
Genetic variants : HAPMAP55435
Genomic Variants (DGV)AP1AR [DGVbeta]
DECIPHER (Syndromes)4:113152895-113191211  ENSG00000138660
CONAN: Copy Number AnalysisAP1AR 
Mutations
ICGC Data PortalAP1AR 
TCGA Data PortalAP1AR 
Broad Tumor PortalAP1AR
OASIS PortalAP1AR [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1AR  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1AR
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1AR
DgiDB (Drug Gene Interaction Database)AP1AR
DoCM (Curated mutations)AP1AR (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1AR (select a term)
intoGenAP1AR
Cancer3DAP1AR(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610851   
Orphanet
MedgenAP1AR
Genetic Testing Registry AP1AR
NextProtQ63HQ0 [Medical]
TSGene55435
GENETestsAP1AR
Huge Navigator AP1AR [HugePedia]
snp3D : Map Gene to Disease55435
BioCentury BCIQAP1AR
ClinGenAP1AR
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55435
Chemical/Pharm GKB GenePA165663153
Clinical trialAP1AR
Miscellaneous
canSAR (ICR)AP1AR (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1AR
EVEXAP1AR
GoPubMedAP1AR
iHOPAP1AR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:37 CET 2017

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