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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

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AP1B1 (adaptor-related protein complex 1, beta 1 subunit)

Identity

Other namesADTB1
AP105A
BAM22
CLAPB2
HGNC (Hugo) AP1B1
LocusID (NCBI) 162
Location 22q12.2
Location_base_pair Starts at 29723669 and ends at 29784572 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AP1B1   554
Cards
Entrez_Gene (NCBI)AP1B1  162  adaptor-related protein complex 1, beta 1 subunit
GeneCards (Weizmann)AP1B1
Ensembl hg19 (Hinxton)ENSG00000100280 [Gene_View]  chr22:29723669-29784572 [Contig_View]  AP1B1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100280 [Gene_View]  chr22:29723669-29784572 [Contig_View]  AP1B1 [Vega]
ICGC DataPortalENSG00000100280
cBioPortalAP1B1
AceView (NCBI)AP1B1
Genatlas (Paris)AP1B1
WikiGenes162
SOURCE (Princeton)AP1B1
Genomic and cartography
GoldenPath hg19 (UCSC)AP1B1  -     chr22:29723669-29784572 -  22q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AP1B1  -     22q12.2   [Description]    (hg38-Dec_2013)
EnsemblAP1B1 - 22q12.2 [CytoView hg19]  AP1B1 - 22q12.2 [CytoView hg38]
Mapping of homologs : NCBIAP1B1 [Mapview hg19]  AP1B1 [Mapview hg38]
OMIM600157   
Gene and transcription
Genbank (Entrez)AI084003 AK294406 AK296567 AK299613 AU139022
RefSeq transcript (Entrez)NM_001127 NM_001166019 NM_145730
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004929430
Consensus coding sequences : CCDS (NCBI)AP1B1
Cluster EST : UnigeneHs.368794 [ NCBI ]
CGAP (NCI)Hs.368794
Alternative Splicing : Fast-db (Paris)GSHG0020289
Alternative Splicing GalleryENSG00000100280
Gene ExpressionAP1B1 [ NCBI-GEO ]     AP1B1 [ SEEK ]   AP1B1 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ10567 (Uniprot)
NextProtQ10567  [Medical]
With graphics : InterProQ10567
Splice isoforms : SwissVarQ10567 (Swissvar)
Domains : Interpro (EBI)AP_beta    AP_complex_bsu_1_2_4    ARM-like    ARM-type_fold    B-adaptin_app_sub_C    Beta2_adaptin/TBP_C_dom    Clathrin/coatomer_adapt-like_N    Clathrin_a/b/g-adaptin_app_Ig    Clathrin_b-adaptin_app_Ig-like    Coatomer/calthrin_app_sub_C    Coatomer/clathrin_app_Ig-like   
Related proteins : CluSTrQ10567
Domain families : Pfam (Sanger)Adaptin_N (PF01602)    Alpha_adaptinC2 (PF02883)    B2-adapt-app_C (PF09066)   
Domain families : Pfam (NCBI)pfam01602    pfam02883    pfam09066   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  B2-adapt-app_C (SM01020)  
DMDM Disease mutations162
Blocks (Seattle)Q10567
PDB (SRS)4HMY   
PDB (PDBSum)4HMY   
PDB (IMB)4HMY   
PDB (RSDB)4HMY   
Human Protein AtlasENSG00000100280
Peptide AtlasQ10567
HPRD02541
IPIIPI00328257   IPI00413947   IPI00940292   IPI00385007   IPI00384489   IPI00946351   IPI00788911   
Protein Interaction databases
DIP (DOE-UCLA)Q10567
IntAct (EBI)Q10567
FunCoupENSG00000100280
BioGRIDAP1B1
IntegromeDBAP1B1
STRING (EMBL)AP1B1
Ontologies - Pathways
QuickGOQ10567
Ontology : AmiGOGolgi membrane  transporter activity  protein binding  lysosomal membrane  cytosol  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  trans-Golgi network membrane  regulation of defense response to virus by virus  membrane organization  
Ontology : EGO-EBIGolgi membrane  transporter activity  protein binding  lysosomal membrane  cytosol  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  trans-Golgi network membrane  regulation of defense response to virus by virus  membrane organization  
Pathways : KEGGLysosome   
Protein Interaction DatabaseAP1B1
DoCM (Curated mutations)AP1B1
Wikipedia pathwaysAP1B1
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerAP1B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1B1
dbVarAP1B1
ClinVarAP1B1
1000_GenomesAP1B1 
Exome Variant ServerAP1B1
SNP (GeneSNP Utah)AP1B1
SNP : HGBaseAP1B1
Genetic variants : HAPMAPAP1B1
Genomic Variants (DGV)AP1B1 [DGVbeta]
Mutations
ICGC Data PortalENSG00000100280 
Somatic Mutations in Cancer : COSMICAP1B1 
CONAN: Copy Number AnalysisAP1B1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:29723669-29784572
Mutations and Diseases : HGMDAP1B1
OMIM600157   
MedgenAP1B1
NextProtQ10567 [Medical]
GENETestsAP1B1
Disease Genetic AssociationAP1B1
Huge Navigator AP1B1 [HugePedia]  AP1B1 [HugeCancerGEM]
snp3D : Map Gene to Disease162
DGIdb (Drug Gene Interaction db)AP1B1
General knowledge
Homologs : HomoloGeneAP1B1
Homology/Alignments : Family Browser (UCSC)AP1B1
Phylogenetic Trees/Animal Genes : TreeFamAP1B1
Chemical/Protein Interactions : CTD162
Chemical/Pharm GKB GenePA24844
Clinical trialAP1B1
Cancer Resource (Charite)ENSG00000100280
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
CoreMineAP1B1
GoPubMedAP1B1
iHOPAP1B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 14:39:51 CET 2015

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