Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AP1B1 (adaptor-related protein complex 1, beta 1 subunit)

Identity

Other namesADTB1
AP105A
BAM22
CLAPB2
HGNC (Hugo) AP1B1
LocusID (NCBI) 162
Location 22q12.2
Location_base_pair Starts at 29723669 and ends at 29784572 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)AP1B1   554
Cards
Entrez_Gene (NCBI)AP1B1  162  adaptor-related protein complex 1, beta 1 subunit
GeneCards (Weizmann)AP1B1
Ensembl (Hinxton)ENSG00000100280 [Gene_View]  chr22:29723669-29784572 [Contig_View]  AP1B1 [Vega]
ICGC DataPortalENSG00000100280
AceView (NCBI)AP1B1
Genatlas (Paris)AP1B1
WikiGenes162
SOURCE (Princeton)NM_001127 NM_001166019 NM_145730
Genomic and cartography
GoldenPath (UCSC)AP1B1  -  22q12.2   chr22:29723669-29784572 -  22q12.2   [Description]    (hg19-Feb_2009)
EnsemblAP1B1 - 22q12.2 [CytoView]
Mapping of homologs : NCBIAP1B1 [Mapview]
OMIM600157   
Gene and transcription
Genbank (Entrez)AI084003 AK294406 AK296567 AK299613 AU139022
RefSeq transcript (Entrez)NM_001127 NM_001166019 NM_145730
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NT_011520 NW_001838745 NW_004929430
Consensus coding sequences : CCDS (NCBI)AP1B1
Cluster EST : UnigeneHs.368794 [ NCBI ]
CGAP (NCI)Hs.368794
Alternative Splicing : Fast-db (Paris)GSHG0020289
Alternative Splicing GalleryENSG00000100280
Gene ExpressionAP1B1 [ NCBI-GEO ]     AP1B1 [ SEEK ]   AP1B1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ10567 (Uniprot)
NextProtQ10567  [Medical]
With graphics : InterProQ10567
Splice isoforms : SwissVarQ10567 (Swissvar)
Domains : Interpro (EBI)AP_beta    AP_complex_bsu_1_2_4    ARM-like    ARM-type_fold    B-adaptin_app_sub_C    Beta2_adaptin/TBP_C_dom    Clathrin/coatomer_adapt-like_N    Clathrin_a/b/g-adaptin_app_Ig    Clathrin_b-adaptin_app_Ig-like    Coatomer/calthrin_app_sub_C    Coatomer/clathrin_app_Ig-like   
Related proteins : CluSTrQ10567
Domain families : Pfam (Sanger)Adaptin_N (PF01602)    Alpha_adaptinC2 (PF02883)    B2-adapt-app_C (PF09066)   
Domain families : Pfam (NCBI)pfam01602    pfam02883    pfam09066   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  B2-adapt-app_C (SM01020)  
DMDM Disease mutations162
Blocks (Seattle)Q10567
PDB (SRS)4HMY   
PDB (PDBSum)4HMY   
PDB (IMB)4HMY   
PDB (RSDB)4HMY   
Human Protein AtlasENSG00000100280
Peptide AtlasQ10567
HPRD02541
IPIIPI00328257   IPI00413947   IPI00940292   IPI00385007   IPI00384489   IPI00946351   IPI00788911   
Protein Interaction databases
DIP (DOE-UCLA)Q10567
IntAct (EBI)Q10567
FunCoupENSG00000100280
BioGRIDAP1B1
IntegromeDBAP1B1
STRING (EMBL)AP1B1
Ontologies - Pathways
QuickGOQ10567
Ontology : AmiGOGolgi membrane  transporter activity  protein binding  lysosomal membrane  cytosol  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  trans-Golgi network membrane  regulation of defense response to virus by virus  membrane organization  
Ontology : EGO-EBIGolgi membrane  transporter activity  protein binding  lysosomal membrane  cytosol  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  protein kinase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  trans-Golgi network membrane  regulation of defense response to virus by virus  membrane organization  
Pathways : KEGGLysosome   
Protein Interaction DatabaseAP1B1
Wikipedia pathwaysAP1B1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)AP1B1
SNP (GeneSNP Utah)AP1B1
SNP : HGBaseAP1B1
Genetic variants : HAPMAPAP1B1
1000_GenomesAP1B1 
ICGC programENSG00000100280 
CONAN: Copy Number AnalysisAP1B1 
Somatic Mutations in Cancer : COSMICAP1B1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)22:29723669-29784572
Mutations and Diseases : HGMDAP1B1
OMIM600157   
MedgenAP1B1
GENETestsAP1B1
Disease Genetic AssociationAP1B1
Huge Navigator AP1B1 [HugePedia]  AP1B1 [HugeCancerGEM]
Genomic VariantsAP1B1  AP1B1 [DGVbeta]
Exome VariantAP1B1
dbVarAP1B1
ClinVarAP1B1
snp3D : Map Gene to Disease162
General knowledge
Homologs : HomoloGeneAP1B1
Homology/Alignments : Family Browser (UCSC)AP1B1
Phylogenetic Trees/Animal Genes : TreeFamAP1B1
Chemical/Protein Interactions : CTD162
Chemical/Pharm GKB GenePA24844
Clinical trialAP1B1
Cancer Resource (Charite)ENSG00000100280
Other databases
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
CoreMineAP1B1
GoPubMedAP1B1
iHOPAP1B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:11:41 CET 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.