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AP1G1 (adaptor related protein complex 1 gamma 1 subunit)

Identity

Alias_namesCLAPG1
ADTG
adaptor-related protein complex 1, gamma 1 subunit
adaptor-related protein complex 1 gamma 1 subunit
Other alias
HGNC (Hugo) AP1G1
LocusID (NCBI) 164
Atlas_Id 60397
Location 16q22.2  [Link to chromosome band 16q22]
Location_base_pair Starts at 71729002 and ends at 71809073 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AP1G1 (16q22.2) / ABCA6 (17q24.2)AP1G1 (16q22.2) / CA12 (15q22.2)AP1G1 (16q22.2) / WDR70 (5p13.2)
MEGF9 (9q33.2) / AP1G1 (16q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

=TD>ĽA LREF=http://www.genenames.org/data/hgnc_data.php?hgnc_id=555 TARGET=HUGO>AP1G1   555
Nomenclature
HGNC (Hugo)
Cards
Entrez_Gene (NCBI)AP1G1  164  adaptor related protein complex 1 gamma 1 subunit
AliasesADTG; CLAPG1
GeneCards (Weizmann)AP1G1
Ensembl hg19 (Hinxton)ENSG00000166747 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166747 [Gene_View]  chr16:71729002-71809073 [Contig_View]  AP1G1 [Vega]
ICGC DataPortalENSG00000166747
TCGA cBioPortalAP1G1
AceView (NCBI)AP1G1
Genatlas (Paris)AP1G1
WikiGenes164
SOURCE (Princeton)AP1G1
Genetics Home Reference (NIH)AP1G1
Genomic and cartography
GoldenPath hg38 (UCSC)AP1G1  -     chr16:71729002-71809073 -  16q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP1G1  -     16q22.2   [Description]    (hg19-Feb_2009)
EnsemblAP1G1 - 16q22.2 [CytoView hg19]  AP1G1 - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBIAP1G1 [Mapview hg19]  AP1G1 [Mapview hg38]
OMIM603533   
Gene and transcription
Genbank (Entrez)AB015317 AK025020 AK055122 AK128078 AK225906
RefSeq transcript (Entrez)NM_001030007 NM_001128
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AP1G1
Cluster EST : UnigeneHs.461253 [ NCBI ]
CGAP (NCI)Hs.461253
Alternative Splicing GalleryENSG00000166747
Gene ExpressionAP1G1 [ NCBI-GEO ]   AP1G1 [ EBI - ARRAY_EXPRESS ]   AP1G1 [ SEEK ]   AP1G1 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1G1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)164
GTEX Portal (Tissue expression)AP1G1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43747   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43747  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43747
Splice isoforms : SwissVarO43747
PhosPhoSitePlusO43747
Domaine pattern : Prosite (Expaxy)GAE (PS50180)   
Domains : Interpro (EBI)AP1_complex_gsu    ARM-like    ARM-type_fold    Clathrin/coatomer_adapt-like_N    Clathrin_a/b/g-adaptin_app_Ig    Clathrin_g-adaptin_app    Coatomer/clathrin_app_Ig-like   
Domain families : Pfam (Sanger)Adaptin_N (PF01602)    Alpha_adaptinC2 (PF02883)   
Domain families : Pfam (NCBI)pfam01602    pfam02883   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  
Conserved Domain (NCBI)AP1G1
DMDM Disease mutations164
Blocks (Seattle)AP1G1
PDB (SRS)1IU1   
PDB (PDBSum)1IU1   
PDB (IMB)1IU1   
PDB (RSDB)1IU1   
Structural Biology KnowledgeBase1IU1   
SCOP (Structural Classification of Proteins)1IU1   
CATH (Classification of proteins structures)1IU1   
SuperfamilyO43747
Human Protein AtlasENSG00000166747
Peptide AtlasO43747
HPRD04637
IPIIPI00939879   IPI00293396   IPI00643591   IPI00909354   IPI00910023   IPI00909722   IPI00816366   IPI01009532   
Protein Interaction databases
DIP (DOE-UCLA)O43747
IntAct (EBI)O43747
FunCoupENSG00000166747
BioGRIDAP1G1
STRING (EMBL)AP1G1
ZODIACAP1G1
Ontologies - Pathways
QuickGOO43747
Ontology : AmiGOGolgi membrane  transporter activity  protein binding  cytoplasm  lysosomal membrane  Golgi apparatus  cytosol  cytosol  intracellular protein transport  protein transporter activity  membrane  Rab GTPase binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  kinesin binding  AP-type membrane coat adaptor complex  clathrin adaptor complex  clathrin-coated vesicle  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  clathrin-coated endocytic vesicle membrane  GTP-dependent protein binding  melanosome organization  trans-Golgi network membrane  endosome to melanosome transport  intracellular membrane-bounded organelle  positive regulation of natural killer cell degranulation  positive regulation of natural killer cell mediated cytotoxicity  regulation of defense response to virus by virus  recycling endosome  Golgi to lysosome transport  
Ontology : EGO-EBIGolgi membrane  transporter activity  protein binding  cytoplasm  lysosomal membrane  Golgi apparatus  cytosol  cytosol  intracellular protein transport  protein transporter activity  membrane  Rab GTPase binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  kinesin binding  AP-type membrane coat adaptor complex  clathrin adaptor complex  clathrin-coated vesicle  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  clathrin-coated endocytic vesicle membrane  GTP-dependent protein binding  melanosome organization  trans-Golgi network membrane  endosome to melanosome transport  intracellular membrane-bounded organelle  positive regulation of natural killer cell degranulation  positive regulation of natural killer cell mediated cytotoxicity  regulation of defense response to virus by virus  recycling endosome  Golgi to lysosome transport  
Pathways : KEGGLysosome   
NDEx NetworkAP1G1
Atlas of Cancer Signalling NetworkAP1G1
Wikipedia pathwaysAP1G1
Orthology - Evolution
OrthoDB164
GeneTree (enSembl)ENSG00000166747
Phylogenetic Trees/Animal Genes : TreeFamAP1G1
HOVERGENO43747
HOGENOMO43747
Homologs : HomoloGeneAP1G1
Homology/Alignments : Family Browser (UCSC)AP1G1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1G1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1G1
dbVarAP1G1
ClinVarAP1G1
1000_GenomesAP1G1 
Exome Variant ServerAP1G1
ExAC (Exome Aggregation Consortium)AP1G1 (select the gene name)
Genetic variants : HAPMAP164
Genomic Variants (DGV)AP1G1 [DGVbeta]
DECIPHERAP1G1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP1G1 
Mutations
ICGC Data PortalAP1G1 
TCGA Data PortalAP1G1 
Broad Tumor PortalAP1G1
OASIS PortalAP1G1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1G1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1G1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1G1
DgiDB (Drug Gene Interaction Database)AP1G1
DoCM (Curated mutations)AP1G1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1G1 (select a term)
intoGenAP1G1
Cancer3DAP1G1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603533   
Orphanet
MedgenAP1G1
Genetic Testing Registry AP1G1
NextProtO43747 [Medical]
TSGene164
GENETestsAP1G1
Target ValidationAP1G1
Huge Navigator AP1G1 [HugePedia]
snp3D : Map Gene to Disease164
BioCentury BCIQAP1G1
ClinGenAP1G1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD164
Chemical/Pharm GKB GenePA24845
Clinical trialAP1G1
Miscellaneous
canSAR (ICR)AP1G1 (select the gene name)
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1G1
EVEXAP1G1
GoPubMedAP1G1
iHOPAP1G1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:31 CEST 2017

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