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AP1G2 (adaptor-related protein complex 1, gamma 2 subunit)

Identity

Alias_namesadaptor-related protein complex 1, gamma 2 subunit
adaptor-related protein complex 1 gamma 2 subunit
Alias_symbol (synonym)G2AD
Other alias
HGNC (Hugo) AP1G2
LocusID (NCBI) 8906
Atlas_Id 60398
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 24028772 and ends at 24037045 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AP1G2 (14q11.2) / HLA-F (6p22.1)AP1G2 (14q11.2) / PTMS (12p13.31)FAM204A (10q26.11) / AP1G2 (14q11.2)
FARSA (19p13.2) / AP1G2 (14q11.2)IGF2 (11p15.5) / AP1G2 (14q11.2)ITGAM (16p11.2) / AP1G2 (14q11.2)
MAPKAP1 (9q33.3) / AP1G2 (14q11.2)RPL7 (8q21.11) / AP1G2 (14q11.2)RPS14 (5q33.1) / AP1G2 (14q11.2)
SDC4 (20q13.12) / AP1G2 (14q11.2)SMPD3 (16q22.1) / AP1G2 (14q11.2)SQSTM1 (5q35.3) / AP1G2 (14q11.2)
THTPA (14q11.2) / AP1G2 (14q11.2)FAM204A AP1G2SMPD3 AP1G2
SQSTM1 AP1G2SDC4 AP1G2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP1G2   556
Cards
Entrez_Gene (NCBI)AP1G2  8906  adaptor-related protein complex 1, gamma 2 subunit
AliasesG2AD
GeneCards (Weizmann)AP1G2
Ensembl hg19 (Hinxton)ENSG00000213983 [Gene_View]  chr14:24028772-24037045 [Contig_View]  AP1G2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000213983 [Gene_View]  chr14:24028772-24037045 [Contig_View]  AP1G2 [Vega]
ICGC DataPortalENSG00000213983
TCGA cBioPortalAP1G2
AceView (NCBI)AP1G2
Genatlas (Paris)AP1G2
WikiGenes8906
SOURCE (Princeton)AP1G2
Genetics Home Reference (NIH)AP1G2
Genomic and cartography
GoldenPath hg19 (UCSC)AP1G2  -     chr14:24028772-24037045 -  14q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AP1G2  -     14q11.2   [Description]    (hg38-Dec_2013)
EnsemblAP1G2 - 14q11.2 [CytoView hg19]  AP1G2 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIAP1G2 [Mapview hg19]  AP1G2 [Mapview hg38]
OMIM603534   
Gene and transcription
Genbank (Entrez)AB015318 AF068706 AI497879 AK096034 AK123354
RefSeq transcript (Entrez)NM_001282474 NM_001282475 NM_003917 NM_080545
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_011937 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)AP1G2
Cluster EST : UnigeneHs.569375 [ NCBI ]
CGAP (NCI)Hs.569375
Alternative Splicing GalleryENSG00000213983
Gene ExpressionAP1G2 [ NCBI-GEO ]   AP1G2 [ EBI - ARRAY_EXPRESS ]   AP1G2 [ SEEK ]   AP1G2 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1G2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8906
GTEX Portal (Tissue expression)AP1G2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75843   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75843  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75843
Splice isoforms : SwissVarO75843
PhosPhoSitePlusO75843
Domaine pattern : Prosite (Expaxy)GAE (PS50180)   
Domains : Interpro (EBI)AP1_complex_gsu    ARM-like    ARM-type_fold    Clathrin/coatomer_adapt-like_N    Clathrin_a/b/g-adaptin_app_Ig    Clathrin_g-adaptin_app    Coatomer/clathrin_app_Ig-like   
Domain families : Pfam (Sanger)Adaptin_N (PF01602)    Alpha_adaptinC2 (PF02883)   
Domain families : Pfam (NCBI)pfam01602    pfam02883   
Domain families : Smart (EMBL)Alpha_adaptinC2 (SM00809)  
Conserved Domain (NCBI)AP1G2
DMDM Disease mutations8906
Blocks (Seattle)AP1G2
PDB (SRS)2E9G    2YMT    3ZHF    4BCX   
PDB (PDBSum)2E9G    2YMT    3ZHF    4BCX   
PDB (IMB)2E9G    2YMT    3ZHF    4BCX   
PDB (RSDB)2E9G    2YMT    3ZHF    4BCX   
Structural Biology KnowledgeBase2E9G    2YMT    3ZHF    4BCX   
SCOP (Structural Classification of Proteins)2E9G    2YMT    3ZHF    4BCX   
CATH (Classification of proteins structures)2E9G    2YMT    3ZHF    4BCX   
SuperfamilyO75843
Human Protein AtlasENSG00000213983
Peptide AtlasO75843
HPRD04638
IPIIPI00027178   IPI01010653   IPI00908750   IPI01025045   IPI01025389   IPI01025270   IPI01025499   IPI01025880   
Protein Interaction databases
DIP (DOE-UCLA)O75843
IntAct (EBI)O75843
FunCoupENSG00000213983
BioGRIDAP1G2
STRING (EMBL)AP1G2
ZODIACAP1G2
Ontologies - Pathways
QuickGOO75843
Ontology : AmiGOGolgi membrane  protein binding  Golgi apparatus  Golgi-associated vesicle  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  endosome membrane  membrane  viral process  vesicle-mediated transport  AP-1 adaptor complex  transport vesicle  membrane organization  
Ontology : EGO-EBIGolgi membrane  protein binding  Golgi apparatus  Golgi-associated vesicle  intracellular protein transport  post-Golgi vesicle-mediated transport  protein transporter activity  endosome membrane  membrane  viral process  vesicle-mediated transport  AP-1 adaptor complex  transport vesicle  membrane organization  
Pathways : KEGGLysosome   
NDEx NetworkAP1G2
Atlas of Cancer Signalling NetworkAP1G2
Wikipedia pathwaysAP1G2
Orthology - Evolution
OrthoDB8906
GeneTree (enSembl)ENSG00000213983
Phylogenetic Trees/Animal Genes : TreeFamAP1G2
HOVERGENO75843
HOGENOMO75843
Homologs : HomoloGeneAP1G2
Homology/Alignments : Family Browser (UCSC)AP1G2
Gene fusions - Rearrangements
Fusion: TCGAFAM204A AP1G2
Fusion: TCGASMPD3 AP1G2
Fusion: TCGASQSTM1 AP1G2
Fusion: TCGASDC4 AP1G2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1G2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1G2
dbVarAP1G2
ClinVarAP1G2
1000_GenomesAP1G2 
Exome Variant ServerAP1G2
ExAC (Exome Aggregation Consortium)AP1G2 (select the gene name)
Genetic variants : HAPMAP8906
Genomic Variants (DGV)AP1G2 [DGVbeta]
DECIPHER (Syndromes)14:24028772-24037045  ENSG00000213983
CONAN: Copy Number AnalysisAP1G2 
Mutations
ICGC Data PortalAP1G2 
TCGA Data PortalAP1G2 
Broad Tumor PortalAP1G2
OASIS PortalAP1G2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1G2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1G2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1G2
DgiDB (Drug Gene Interaction Database)AP1G2
DoCM (Curated mutations)AP1G2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1G2 (select a term)
intoGenAP1G2
Cancer3DAP1G2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603534   
Orphanet
MedgenAP1G2
Genetic Testing Registry AP1G2
NextProtO75843 [Medical]
TSGene8906
GENETestsAP1G2
Huge Navigator AP1G2 [HugePedia]
snp3D : Map Gene to Disease8906
BioCentury BCIQAP1G2
ClinGenAP1G2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8906
Chemical/Pharm GKB GenePA24846
Clinical trialAP1G2
Miscellaneous
canSAR (ICR)AP1G2 (select the gene name)
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1G2
EVEXAP1G2
GoPubMedAP1G2
iHOPAP1G2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:37 CET 2017

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