Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AP1M1 (adaptor related protein complex 1 subunit mu 1)

Identity

Alias (NCBI)AP47
CLAPM2
CLTNM
MU-1A
mu1A
HGNC (Hugo) AP1M1
HGNC Alias symbAP47
CLAPM2
HGNC Previous nameadaptor-related protein complex 1, mu 1 subunit
 adaptor-related protein complex 1 mu 1 subunit
LocusID (NCBI) 8907
Atlas_Id 60399
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 16197911 and ends at 16245903 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AP1M1 (19p13.11)::CYP4F11 (19p13.12)AP1M1 (19p13.11)::RAB8A (19p13.12)AP1M1 (19p13.11)::ZNF93 (19p12)
CLPTM1 (19q13.32)::AP1M1 (19p13.11)DNMT1 (19p13.2)::AP1M1 (19p13.11)AP1M1 RAB8A
AP1M1 ZNF93AP1M1 CYP4F11DNMT1 AP1M1
CLPTM1 AP1M1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AP1M1   13667
Cards
Entrez_Gene (NCBI)AP1M1    adaptor related protein complex 1 subunit mu 1
AliasesAP47; CLAPM2; CLTNM; MU-1A; 
mu1A
GeneCards (Weizmann)AP1M1
Ensembl hg19 (Hinxton)ENSG00000072958 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000072958 [Gene_View]  ENSG00000072958 [Sequence]  chr19:16197911-16245903 [Contig_View]  AP1M1 [Vega]
ICGC DataPortalENSG00000072958
TCGA cBioPortalAP1M1
AceView (NCBI)AP1M1
Genatlas (Paris)AP1M1
SOURCE (Princeton)AP1M1
Genetics Home Reference (NIH)AP1M1
Genomic and cartography
GoldenPath hg38 (UCSC)AP1M1  -     chr19:16197911-16245903 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP1M1  -     19p13.11   [Description]    (hg19-Feb_2009)
GoldenPathAP1M1 - 19p13.11 [CytoView hg19]  AP1M1 - 19p13.11 [CytoView hg38]
ImmunoBaseENSG00000072958
Genome Data Viewer NCBIAP1M1 [Mapview hg19]  
OMIM603535   
Gene and transcription
Genbank (Entrez)AB209808 AF290613 AK027528 AK293188 AK297824
RefSeq transcript (Entrez)NM_001130524 NM_032493
Consensus coding sequences : CCDS (NCBI)AP1M1
Gene ExpressionAP1M1 [ NCBI-GEO ]   AP1M1 [ EBI - ARRAY_EXPRESS ]   AP1M1 [ SEEK ]   AP1M1 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1M1 [ Firebrowse - Broad ]
GenevisibleExpression of AP1M1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8907
GTEX Portal (Tissue expression)AP1M1
Human Protein AtlasENSG00000072958-AP1M1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXS5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXS5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXS5
PhosPhoSitePlusQ9BXS5
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_M_1 (PS00990)    CLAT_ADAPTOR_M_2 (PS00991)    MHD (PS51072)   
Domains : Interpro (EBI)AP2_Mu_C_sf    Clathrin_mu    Clathrin_mu_CS    Longin-like_dom_sf    MHD   
Domain families : Pfam (Sanger)Adap_comp_sub (PF00928)   
Domain families : Pfam (NCBI)pfam00928   
Conserved Domain (NCBI)AP1M1
SuperfamilyQ9BXS5
AlphaFold pdb e-kbQ9BXS5   
Human Protein Atlas [tissue]ENSG00000072958-AP1M1 [tissue]
HPRD04639
Protein Interaction databases
DIP (DOE-UCLA)Q9BXS5
IntAct (EBI)Q9BXS5
BioGRIDAP1M1
STRING (EMBL)AP1M1
ZODIACAP1M1
Ontologies - Pathways
QuickGOQ9BXS5
Ontology : AmiGOGolgi membrane  protein binding  lysosomal membrane  cytosol  plasma membrane  intracellular protein transport  post-Golgi vesicle-mediated transport  membrane  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  clathrin-coated vesicle  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  cytoplasmic vesicle  melanosome organization  trans-Golgi network membrane  specific granule membrane  clathrin adaptor activity  endosome to melanosome transport  intracellular membrane-bounded organelle  neutrophil degranulation  regulation of defense response to virus by virus  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  protein binding  lysosomal membrane  cytosol  plasma membrane  intracellular protein transport  post-Golgi vesicle-mediated transport  membrane  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  clathrin-coated vesicle  cytoplasmic vesicle membrane  clathrin-coated vesicle membrane  cytoplasmic vesicle  melanosome organization  trans-Golgi network membrane  specific granule membrane  clathrin adaptor activity  endosome to melanosome transport  intracellular membrane-bounded organelle  neutrophil degranulation  regulation of defense response to virus by virus  extracellular exosome  
NDEx NetworkAP1M1
Atlas of Cancer Signalling NetworkAP1M1
Wikipedia pathwaysAP1M1
Orthology - Evolution
OrthoDB8907
GeneTree (enSembl)ENSG00000072958
Phylogenetic Trees/Animal Genes : TreeFamAP1M1
Homologs : HomoloGeneAP1M1
Homology/Alignments : Family Browser (UCSC)AP1M1
Gene fusions - Rearrangements
Fusion : QuiverAP1M1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1M1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1M1
dbVarAP1M1
ClinVarAP1M1
MonarchAP1M1
1000_GenomesAP1M1 
Exome Variant ServerAP1M1
GNOMAD BrowserENSG00000072958
Varsome BrowserAP1M1
ACMGAP1M1 variants
VarityQ9BXS5
Genomic Variants (DGV)AP1M1 [DGVbeta]
DECIPHERAP1M1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP1M1 
Mutations
ICGC Data PortalAP1M1 
TCGA Data PortalAP1M1 
Broad Tumor PortalAP1M1
OASIS PortalAP1M1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1M1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAP1M1
Mutations and Diseases : HGMDAP1M1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAP1M1
DgiDB (Drug Gene Interaction Database)AP1M1
DoCM (Curated mutations)AP1M1
CIViC (Clinical Interpretations of Variants in Cancer)AP1M1
Cancer3DAP1M1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603535   
Orphanet
DisGeNETAP1M1
MedgenAP1M1
Genetic Testing Registry AP1M1
NextProtQ9BXS5 [Medical]
GENETestsAP1M1
Target ValidationAP1M1
Huge Navigator AP1M1 [HugePedia]
ClinGenAP1M1
Clinical trials, drugs, therapy
MyCancerGenomeAP1M1
Protein Interactions : CTDAP1M1
Pharm GKB GenePA24848
PharosQ9BXS5
Clinical trialAP1M1
Miscellaneous
canSAR (ICR)AP1M1
HarmonizomeAP1M1
ARCHS4AP1M1
DataMed IndexAP1M1
Probes
Litterature
PubMed121 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAP1M1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun Jan 16 18:44:48 CET 2022

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.