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AP1M1 (adaptor related protein complex 1 mu 1 subunit)

Identity

Alias_namesadaptor-related protein complex 1, mu 1 subunit
adaptor-related protein complex 1 mu 1 subunit
Alias_symbol (synonym)AP47
CLAPM2
Other aliasCLTNM
MU-1A
HGNC (Hugo) AP1M1
LocusID (NCBI) 8907
Atlas_Id 60399
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 16197854 and ends at 16235345 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AP1M1 (19p13.11) / CYP4F11 (19p13.12)AP1M1 (19p13.11) / RAB8A (19p13.12)AP1M1 (19p13.11) / ZNF93 (19p12)
CLPTM1 (19q13.32) / AP1M1 (19p13.11)DNMT1 (19p13.2) / AP1M1 (19p13.11)AP1M1 RAB8A
AP1M1 ZNF93AP1M1 CYP4F11DNMT1 AP1M1
CLPTM1 AP1M1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP1M1   13667
Cards
Entrez_Gene (NCBI)AP1M1  8907  adaptor related protein complex 1 mu 1 subunit
AliasesAP47; CLAPM2; CLTNM; MU-1A
GeneCards (Weizmann)AP1M1
Ensembl hg19 (Hinxton)ENSG00000072958 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000072958 [Gene_View]  chr19:16197854-16235345 [Contig_View]  AP1M1 [Vega]
ICGC DataPortalENSG00000072958
TCGA cBioPortalAP1M1
AceView (NCBI)AP1M1
Genatlas (Paris)AP1M1
WikiGenes8907
SOURCE (Princeton)AP1M1
Genetics Home Reference (NIH)AP1M1
Genomic and cartography
GoldenPath hg38 (UCSC)AP1M1  -     chr19:16197854-16235345 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP1M1  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblAP1M1 - 19p13.11 [CytoView hg19]  AP1M1 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIAP1M1 [Mapview hg19]  AP1M1 [Mapview hg38]
OMIM603535   
Gene and transcription
Genbank (Entrez)AB209808 AF290613 AK027528 AK293188 AK297824
RefSeq transcript (Entrez)NM_001130524 NM_032493
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AP1M1
Cluster EST : UnigeneHs.71040 [ NCBI ]
CGAP (NCI)Hs.71040
Alternative Splicing GalleryENSG00000072958
Gene ExpressionAP1M1 [ NCBI-GEO ]   AP1M1 [ EBI - ARRAY_EXPRESS ]   AP1M1 [ SEEK ]   AP1M1 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1M1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8907
GTEX Portal (Tissue expression)AP1M1
Human Protein AtlasENSG00000072958-AP1M1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BXS5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BXS5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BXS5
Splice isoforms : SwissVarQ9BXS5
PhosPhoSitePlusQ9BXS5
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_M_1 (PS00990)    CLAT_ADAPTOR_M_2 (PS00991)    MHD (PS51072)   
Domains : Interpro (EBI)AP_mu_sigma_su    Clathrin_mu    Clathrin_mu_CS    Longin-like_dom    MHD   
Domain families : Pfam (Sanger)Adap_comp_sub (PF00928)    Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam00928    pfam01217   
Conserved Domain (NCBI)AP1M1
DMDM Disease mutations8907
Blocks (Seattle)AP1M1
SuperfamilyQ9BXS5
Human Protein Atlas [tissue]ENSG00000072958-AP1M1 [tissue]
Peptide AtlasQ9BXS5
HPRD04639
IPIIPI00032516   IPI01012853   IPI00910344   IPI00910088   
Protein Interaction databases
DIP (DOE-UCLA)Q9BXS5
IntAct (EBI)Q9BXS5
FunCoupENSG00000072958
BioGRIDAP1M1
STRING (EMBL)AP1M1
ZODIACAP1M1
Ontologies - Pathways
QuickGOQ9BXS5
Ontology : AmiGOGolgi membrane  protein binding  lysosomal membrane  cytosol  plasma membrane  intracellular protein transport  membrane  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  melanosome organization  trans-Golgi network membrane  specific granule membrane  endosome to melanosome transport  neutrophil degranulation  regulation of defense response to virus by virus  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  protein binding  lysosomal membrane  cytosol  plasma membrane  intracellular protein transport  membrane  viral process  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin adaptor complex  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  melanosome organization  trans-Golgi network membrane  specific granule membrane  endosome to melanosome transport  neutrophil degranulation  regulation of defense response to virus by virus  extracellular exosome  
Pathways : KEGGLysosome   
NDEx NetworkAP1M1
Atlas of Cancer Signalling NetworkAP1M1
Wikipedia pathwaysAP1M1
Orthology - Evolution
OrthoDB8907
GeneTree (enSembl)ENSG00000072958
Phylogenetic Trees/Animal Genes : TreeFamAP1M1
HOVERGENQ9BXS5
HOGENOMQ9BXS5
Homologs : HomoloGeneAP1M1
Homology/Alignments : Family Browser (UCSC)AP1M1
Gene fusions - Rearrangements
Fusion: TCGA_MDACCAP1M1 RAB8A
Fusion: TCGA_MDACCAP1M1 ZNF93
Fusion: TCGA_MDACCAP1M1 CYP4F11
Fusion: TCGA_MDACCDNMT1 AP1M1
Fusion: TCGA_MDACCCLPTM1 AP1M1
Tumor Fusion PortalAP1M1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1M1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1M1
dbVarAP1M1
ClinVarAP1M1
1000_GenomesAP1M1 
Exome Variant ServerAP1M1
ExAC (Exome Aggregation Consortium)ENSG00000072958
GNOMAD BrowserENSG00000072958
Genetic variants : HAPMAP8907
Genomic Variants (DGV)AP1M1 [DGVbeta]
DECIPHERAP1M1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP1M1 
Mutations
ICGC Data PortalAP1M1 
TCGA Data PortalAP1M1 
Broad Tumor PortalAP1M1
OASIS PortalAP1M1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1M1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1M1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1M1
DgiDB (Drug Gene Interaction Database)AP1M1
DoCM (Curated mutations)AP1M1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1M1 (select a term)
intoGenAP1M1
Cancer3DAP1M1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603535   
Orphanet
DisGeNETAP1M1
MedgenAP1M1
Genetic Testing Registry AP1M1
NextProtQ9BXS5 [Medical]
TSGene8907
GENETestsAP1M1
Target ValidationAP1M1
Huge Navigator AP1M1 [HugePedia]
snp3D : Map Gene to Disease8907
BioCentury BCIQAP1M1
ClinGenAP1M1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8907
Chemical/Pharm GKB GenePA24848
Clinical trialAP1M1
Miscellaneous
canSAR (ICR)AP1M1 (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1M1
EVEXAP1M1
GoPubMedAP1M1
iHOPAP1M1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:38:07 CET 2017

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