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AP1S3 (adaptor related protein complex 1 sigma 3 subunit)

Identity

Alias_namesadaptor-related protein complex 1, sigma 3 subunit
adaptor-related protein complex 1 sigma 3 subunit
Other aliasPSORS15
HGNC (Hugo) AP1S3
LocusID (NCBI) 130340
Atlas_Id 54045
Location 2q36.1  [Link to chromosome band 2q36]
Location_base_pair Starts at 223755330 and ends at 223837602 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AP1S3 (2q36.1) / PDSS2 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP1S3   18971
Cards
Entrez_Gene (NCBI)AP1S3  130340  adaptor related protein complex 1 sigma 3 subunit
AliasesPSORS15
GeneCards (Weizmann)AP1S3
Ensembl hg19 (Hinxton)ENSG00000152056 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152056 [Gene_View]  chr2:223755330-223837602 [Contig_View]  AP1S3 [Vega]
ICGC DataPortalENSG00000152056
TCGA cBioPortalAP1S3
AceView (NCBI)AP1S3
Genatlas (Paris)AP1S3
WikiGenes130340
SOURCE (Princeton)AP1S3
Genetics Home Reference (NIH)AP1S3
Genomic and cartography
GoldenPath hg38 (UCSC)AP1S3  -     chr2:223755330-223837602 -  2q36.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP1S3  -     2q36.1   [Description]    (hg19-Feb_2009)
EnsemblAP1S3 - 2q36.1 [CytoView hg19]  AP1S3 - 2q36.1 [CytoView hg38]
Mapping of homologs : NCBIAP1S3 [Mapview hg19]  AP1S3 [Mapview hg38]
OMIM615781   616106   
Gene and transcription
Genbank (Entrez)AF393369 AK025338 AK299026 BC009606 BC021898
RefSeq transcript (Entrez)NM_001039569 NM_178814
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AP1S3
Cluster EST : UnigeneHs.632555 [ NCBI ]
CGAP (NCI)Hs.632555
Alternative Splicing GalleryENSG00000152056
Gene ExpressionAP1S3 [ NCBI-GEO ]   AP1S3 [ EBI - ARRAY_EXPRESS ]   AP1S3 [ SEEK ]   AP1S3 [ MEM ]
Gene Expression Viewer (FireBrowse)AP1S3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)130340
GTEX Portal (Tissue expression)AP1S3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PC3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PC3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PC3
Splice isoforms : SwissVarQ96PC3
PhosPhoSitePlusQ96PC3
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_S (PS00989)   
Domains : Interpro (EBI)AP_complex_ssu    AP_mu_sigma_su    Clathrin_sm-chain_CS    Longin-like_dom   
Domain families : Pfam (Sanger)Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam01217   
Conserved Domain (NCBI)AP1S3
DMDM Disease mutations130340
Blocks (Seattle)AP1S3
PDB (SRS)4HMY   
PDB (PDBSum)4HMY   
PDB (IMB)4HMY   
PDB (RSDB)4HMY   
Structural Biology KnowledgeBase4HMY   
SCOP (Structural Classification of Proteins)4HMY   
CATH (Classification of proteins structures)4HMY   
SuperfamilyQ96PC3
Human Protein AtlasENSG00000152056
Peptide AtlasQ96PC3
HPRD16495
IPIIPI00060866   IPI00654799   IPI00915398   IPI00937280   IPI00917154   IPI01012060   IPI00916845   IPI00917197   
Protein Interaction databases
DIP (DOE-UCLA)Q96PC3
IntAct (EBI)Q96PC3
FunCoupENSG00000152056
BioGRIDAP1S3
STRING (EMBL)AP1S3
ZODIACAP1S3
Ontologies - Pathways
QuickGOQ96PC3
Ontology : AmiGOGolgi membrane  protein binding  lysosomal membrane  cytosol  clathrin-coated pit  protein targeting  protein transporter activity  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  membrane coat  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  trans-Golgi network membrane  intracellular membrane-bounded organelle  regulation of defense response to virus by virus  
Ontology : EGO-EBIGolgi membrane  protein binding  lysosomal membrane  cytosol  clathrin-coated pit  protein targeting  protein transporter activity  vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  membrane coat  cytoplasmic vesicle membrane  clathrin-coated endocytic vesicle membrane  trans-Golgi network membrane  intracellular membrane-bounded organelle  regulation of defense response to virus by virus  
Pathways : KEGGLysosome   
NDEx NetworkAP1S3
Atlas of Cancer Signalling NetworkAP1S3
Wikipedia pathwaysAP1S3
Orthology - Evolution
OrthoDB130340
GeneTree (enSembl)ENSG00000152056
Phylogenetic Trees/Animal Genes : TreeFamAP1S3
HOVERGENQ96PC3
HOGENOMQ96PC3
Homologs : HomoloGeneAP1S3
Homology/Alignments : Family Browser (UCSC)AP1S3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP1S3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP1S3
dbVarAP1S3
ClinVarAP1S3
1000_GenomesAP1S3 
Exome Variant ServerAP1S3
ExAC (Exome Aggregation Consortium)AP1S3 (select the gene name)
Genetic variants : HAPMAP130340
Genomic Variants (DGV)AP1S3 [DGVbeta]
DECIPHERAP1S3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP1S3 
Mutations
ICGC Data PortalAP1S3 
TCGA Data PortalAP1S3 
Broad Tumor PortalAP1S3
OASIS PortalAP1S3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP1S3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP1S3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP1S3
DgiDB (Drug Gene Interaction Database)AP1S3
DoCM (Curated mutations)AP1S3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP1S3 (select a term)
intoGenAP1S3
Cancer3DAP1S3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615781    616106   
Orphanet17549    17548    19519   
MedgenAP1S3
Genetic Testing Registry AP1S3
NextProtQ96PC3 [Medical]
TSGene130340
GENETestsAP1S3
Huge Navigator AP1S3 [HugePedia]
snp3D : Map Gene to Disease130340
BioCentury BCIQAP1S3
ClinGenAP1S3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD130340
Chemical/Pharm GKB GenePA134866785
Clinical trialAP1S3
Miscellaneous
canSAR (ICR)AP1S3 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP1S3
EVEXAP1S3
GoPubMedAP1S3
iHOPAP1S3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:06:10 CEST 2017

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