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AP3M1 (adaptor-related protein complex 3, mu 1 subunit)

Identity

Alias_namesadaptor-related protein complex 3, mu 1 subunit
Other alias-
HGNC (Hugo) AP3M1
LocusID (NCBI) 26985
Atlas_Id 60404
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 75880015 and ends at 75910826 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
AP3M1 (10q22.2) / IFFO2 (1p36.13)BRPF1 (3p25.3) / AP3M1 (10q22.2)IFFO2 (1p36.13) / AP3M1 (10q22.2)
TSC22D3 (Xq22.3) / AP3M1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP3M1   569
Cards
Entrez_Gene (NCBI)AP3M1  26985  adaptor-related protein complex 3, mu 1 subunit
Aliases
GeneCards (Weizmann)AP3M1
Ensembl hg19 (Hinxton)ENSG00000185009 [Gene_View]  chr10:75880015-75910826 [Contig_View]  AP3M1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000185009 [Gene_View]  chr10:75880015-75910826 [Contig_View]  AP3M1 [Vega]
ICGC DataPortalENSG00000185009
TCGA cBioPortalAP3M1
AceView (NCBI)AP3M1
Genatlas (Paris)AP3M1
WikiGenes26985
SOURCE (Princeton)AP3M1
Genetics Home Reference (NIH)AP3M1
Genomic and cartography
GoldenPath hg19 (UCSC)AP3M1  -     chr10:75880015-75910826 -  10q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)AP3M1  -     10q22.2   [Description]    (hg38-Dec_2013)
EnsemblAP3M1 - 10q22.2 [CytoView hg19]  AP3M1 - 10q22.2 [CytoView hg38]
Mapping of homologs : NCBIAP3M1 [Mapview hg19]  AP3M1 [Mapview hg38]
OMIM610366   
Gene and transcription
Genbank (Entrez)AF092092 AI610802 AK001565 AK026983 AK299352
RefSeq transcript (Entrez)NM_012095 NM_207012
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)AP3M1
Cluster EST : UnigeneHs.500104 [ NCBI ]
CGAP (NCI)Hs.500104
Alternative Splicing GalleryENSG00000185009
Gene ExpressionAP3M1 [ NCBI-GEO ]   AP3M1 [ EBI - ARRAY_EXPRESS ]   AP3M1 [ SEEK ]   AP3M1 [ MEM ]
Gene Expression Viewer (FireBrowse)AP3M1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26985
GTEX Portal (Tissue expression)AP3M1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2T2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2T2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2T2
Splice isoforms : SwissVarQ9Y2T2
PhosPhoSitePlusQ9Y2T2
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_M_1 (PS00990)    CLAT_ADAPTOR_M_2 (PS00991)    MHD (PS51072)   
Domains : Interpro (EBI)AP_mu_sigma_su    Clathrin_mu    Clathrin_mu_C    Clathrin_mu_CS    Longin-like_dom    MHD   
Domain families : Pfam (Sanger)Adap_comp_sub (PF00928)    Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam00928    pfam01217   
Conserved Domain (NCBI)AP3M1
DMDM Disease mutations26985
Blocks (Seattle)AP3M1
SuperfamilyQ9Y2T2
Human Protein AtlasENSG00000185009
Peptide AtlasQ9Y2T2
HPRD16496
IPIIPI00032459   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2T2
IntAct (EBI)Q9Y2T2
FunCoupENSG00000185009
BioGRIDAP3M1
STRING (EMBL)AP3M1
ZODIACAP3M1
Ontologies - Pathways
QuickGOQ9Y2T2
Ontology : AmiGOprotein binding  lysosome  lysosomal membrane  Golgi apparatus  protein targeting to lysosome  anterograde axon cargo transport  Rab GTPase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  anterograde synaptic vesicle transport  
Ontology : EGO-EBIprotein binding  lysosome  lysosomal membrane  Golgi apparatus  protein targeting to lysosome  anterograde axon cargo transport  Rab GTPase binding  clathrin adaptor complex  cytoplasmic vesicle membrane  anterograde synaptic vesicle transport  
Pathways : KEGGLysosome   
NDEx NetworkAP3M1
Atlas of Cancer Signalling NetworkAP3M1
Wikipedia pathwaysAP3M1
Orthology - Evolution
OrthoDB26985
GeneTree (enSembl)ENSG00000185009
Phylogenetic Trees/Animal Genes : TreeFamAP3M1
HOVERGENQ9Y2T2
HOGENOMQ9Y2T2
Homologs : HomoloGeneAP3M1
Homology/Alignments : Family Browser (UCSC)AP3M1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP3M1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP3M1
dbVarAP3M1
ClinVarAP3M1
1000_GenomesAP3M1 
Exome Variant ServerAP3M1
ExAC (Exome Aggregation Consortium)AP3M1 (select the gene name)
Genetic variants : HAPMAP26985
Genomic Variants (DGV)AP3M1 [DGVbeta]
DECIPHER (Syndromes)10:75880015-75910826  ENSG00000185009
CONAN: Copy Number AnalysisAP3M1 
Mutations
ICGC Data PortalAP3M1 
TCGA Data PortalAP3M1 
Broad Tumor PortalAP3M1
OASIS PortalAP3M1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP3M1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP3M1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP3M1
DgiDB (Drug Gene Interaction Database)AP3M1
DoCM (Curated mutations)AP3M1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP3M1 (select a term)
intoGenAP3M1
Cancer3DAP3M1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610366   
Orphanet
MedgenAP3M1
Genetic Testing Registry AP3M1
NextProtQ9Y2T2 [Medical]
TSGene26985
GENETestsAP3M1
Huge Navigator AP3M1 [HugePedia]
snp3D : Map Gene to Disease26985
BioCentury BCIQAP3M1
ClinGenAP3M1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26985
Chemical/Pharm GKB GenePA24860
Clinical trialAP3M1
Miscellaneous
canSAR (ICR)AP3M1 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP3M1
EVEXAP3M1
GoPubMedAP3M1
iHOPAP3M1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:39 CET 2017

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