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AP3M1 (adaptor related protein complex 3 subunit mu 1)

Identity

Alias (NCBI)-
HGNC (Hugo) AP3M1
HGNC Previous nameadaptor-related protein complex 3, mu 1 subunit
LocusID (NCBI) 26985
Atlas_Id 60404
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 74120255 and ends at 74150828 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AP3M1 (10q22.2) / IFFO2 (1p36.13)BRPF1 (3p25.3) / AP3M1 (10q22.2)IFFO2 (1p36.13) / AP3M1 (10q22.2)
TSC22D3 (Xq22.3) / AP3M1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)AP3M1   569
Cards
Entrez_Gene (NCBI)AP3M1    adaptor related protein complex 3 subunit mu 1
Aliases
GeneCards (Weizmann)AP3M1
Ensembl hg19 (Hinxton)ENSG00000185009 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185009 [Gene_View]  ENSG00000185009 [Sequence]  chr10:74120255-74150828 [Contig_View]  AP3M1 [Vega]
ICGC DataPortalENSG00000185009
TCGA cBioPortalAP3M1
AceView (NCBI)AP3M1
Genatlas (Paris)AP3M1
SOURCE (Princeton)AP3M1
Genetics Home Reference (NIH)AP3M1
Genomic and cartography
GoldenPath hg38 (UCSC)AP3M1  -     chr10:74120255-74150828 -  10q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP3M1  -     10q22.2   [Description]    (hg19-Feb_2009)
GoldenPathAP3M1 - 10q22.2 [CytoView hg19]  AP3M1 - 10q22.2 [CytoView hg38]
ImmunoBaseENSG00000185009
Genome Data Viewer NCBIAP3M1 [Mapview hg19]  
OMIM610366   
Gene and transcription
Genbank (Entrez)AF092092 AI610802 AK001565 AK026983 AK299352
RefSeq transcript (Entrez)NM_001320263 NM_001320264 NM_001320265 NM_012095 NM_207012
Consensus coding sequences : CCDS (NCBI)AP3M1
Gene ExpressionAP3M1 [ NCBI-GEO ]   AP3M1 [ EBI - ARRAY_EXPRESS ]   AP3M1 [ SEEK ]   AP3M1 [ MEM ]
Gene Expression Viewer (FireBrowse)AP3M1 [ Firebrowse - Broad ]
GenevisibleExpression of AP3M1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26985
GTEX Portal (Tissue expression)AP3M1
Human Protein AtlasENSG00000185009-AP3M1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2T2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2T2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2T2
PhosPhoSitePlusQ9Y2T2
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_M_1 (PS00990)    CLAT_ADAPTOR_M_2 (PS00991)    MHD (PS51072)   
Domains : Interpro (EBI)AP2_Mu_C_sf    AP_mu_sigma_su    Clathrin_mu    Clathrin_mu_CS    Longin-like_dom_sf    MHD   
Domain families : Pfam (Sanger)Adap_comp_sub (PF00928)    Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam00928    pfam01217   
Conserved Domain (NCBI)AP3M1
SuperfamilyQ9Y2T2
AlphaFold pdb e-kbQ9Y2T2   
Human Protein Atlas [tissue]ENSG00000185009-AP3M1 [tissue]
HPRD16496
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2T2
IntAct (EBI)Q9Y2T2
BioGRIDAP3M1
STRING (EMBL)AP3M1
ZODIACAP3M1
Ontologies - Pathways
QuickGOQ9Y2T2
Ontology : AmiGOprotein binding  lysosome  lysosomal membrane  Golgi apparatus  protein targeting to lysosome  endocytosis  anterograde axonal transport  vesicle-mediated transport  clathrin adaptor complex  cytoplasmic vesicle membrane  small GTPase binding  cytoplasmic vesicle  intracellular membrane-bounded organelle  anterograde synaptic vesicle transport  axon cytoplasm  
Ontology : EGO-EBIprotein binding  lysosome  lysosomal membrane  Golgi apparatus  protein targeting to lysosome  endocytosis  anterograde axonal transport  vesicle-mediated transport  clathrin adaptor complex  cytoplasmic vesicle membrane  small GTPase binding  cytoplasmic vesicle  intracellular membrane-bounded organelle  anterograde synaptic vesicle transport  axon cytoplasm  
NDEx NetworkAP3M1
Atlas of Cancer Signalling NetworkAP3M1
Wikipedia pathwaysAP3M1
Orthology - Evolution
OrthoDB26985
GeneTree (enSembl)ENSG00000185009
Phylogenetic Trees/Animal Genes : TreeFamAP3M1
Homologs : HomoloGeneAP3M1
Homology/Alignments : Family Browser (UCSC)AP3M1
Gene fusions - Rearrangements
Fusion : QuiverAP3M1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP3M1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP3M1
dbVarAP3M1
ClinVarAP3M1
MonarchAP3M1
1000_GenomesAP3M1 
Exome Variant ServerAP3M1
GNOMAD BrowserENSG00000185009
Varsome BrowserAP3M1
ACMGAP3M1 variants
VarityQ9Y2T2
Genomic Variants (DGV)AP3M1 [DGVbeta]
DECIPHERAP3M1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP3M1 
Mutations
ICGC Data PortalAP3M1 
TCGA Data PortalAP3M1 
Broad Tumor PortalAP3M1
OASIS PortalAP3M1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP3M1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAP3M1
Mutations and Diseases : HGMDAP3M1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaAP3M1
DgiDB (Drug Gene Interaction Database)AP3M1
DoCM (Curated mutations)AP3M1
CIViC (Clinical Interpretations of Variants in Cancer)AP3M1
Cancer3DAP3M1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610366   
Orphanet
DisGeNETAP3M1
MedgenAP3M1
Genetic Testing Registry AP3M1
NextProtQ9Y2T2 [Medical]
GENETestsAP3M1
Target ValidationAP3M1
Huge Navigator AP3M1 [HugePedia]
ClinGenAP3M1
Clinical trials, drugs, therapy
MyCancerGenomeAP3M1
Protein Interactions : CTDAP3M1
Pharm GKB GenePA24860
PharosQ9Y2T2
Clinical trialAP3M1
Miscellaneous
canSAR (ICR)AP3M1
HarmonizomeAP3M1
DataMed IndexAP3M1
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXAP3M1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:42:18 CEST 2021

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