Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

AP3S2 (adaptor related protein complex 3 sigma 2 subunit)

Identity

Alias_namesadaptor-related protein complex 3, sigma 2 subunit
Alias_symbol (synonym)sigma3b
Other aliasAP3S3
HGNC (Hugo) AP3S2
LocusID (NCBI) 10239
Atlas_Id 60406
Location 15q26.1  [Link to chromosome band 15q26]
Location_base_pair Starts at 89830599 and ends at 89894385 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANPEP (15q26.1) / AP3S2 (15q26.1)AP3S2 (15q26.1) / ANK2 (4q25)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)AP3S2   571
Cards
Entrez_Gene (NCBI)AP3S2  10239  adaptor related protein complex 3 sigma 2 subunit
AliasesAP3S3; sigma3b
GeneCards (Weizmann)AP3S2
Ensembl hg19 (Hinxton)ENSG00000157823 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157823 [Gene_View]  chr15:89830599-89894385 [Contig_View]  AP3S2 [Vega]
ICGC DataPortalENSG00000157823
TCGA cBioPortalAP3S2
AceView (NCBI)AP3S2
Genatlas (Paris)AP3S2
WikiGenes10239
SOURCE (Princeton)AP3S2
Genetics Home Reference (NIH)AP3S2
Genomic and cartography
GoldenPath hg38 (UCSC)AP3S2  -     chr15:89830599-89894385 -  15q26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AP3S2  -     15q26.1   [Description]    (hg19-Feb_2009)
EnsemblAP3S2 - 15q26.1 [CytoView hg19]  AP3S2 - 15q26.1 [CytoView hg38]
Mapping of homologs : NCBIAP3S2 [Mapview hg19]  AP3S2 [Mapview hg38]
OMIM602416   
Gene and transcription
Genbank (Entrez)AK222698 AK294712 AK312467 AL109702 AL110108
RefSeq transcript (Entrez)NM_005829
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AP3S2
Cluster EST : UnigeneHs.632161 [ NCBI ]
CGAP (NCI)Hs.632161
Alternative Splicing GalleryENSG00000157823
Gene ExpressionAP3S2 [ NCBI-GEO ]   AP3S2 [ EBI - ARRAY_EXPRESS ]   AP3S2 [ SEEK ]   AP3S2 [ MEM ]
Gene Expression Viewer (FireBrowse)AP3S2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10239
GTEX Portal (Tissue expression)AP3S2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP59780   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP59780  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP59780
Splice isoforms : SwissVarP59780
PhosPhoSitePlusP59780
Domaine pattern : Prosite (Expaxy)CLAT_ADAPTOR_S (PS00989)   
Domains : Interpro (EBI)AP_complex_ssu    AP_mu_sigma_su    Clathrin_sm-chain_CS    Longin-like_dom   
Domain families : Pfam (Sanger)Clat_adaptor_s (PF01217)   
Domain families : Pfam (NCBI)pfam01217   
Conserved Domain (NCBI)AP3S2
DMDM Disease mutations10239
Blocks (Seattle)AP3S2
SuperfamilyP59780
Human Protein AtlasENSG00000157823
Peptide AtlasP59780
HPRD03880
IPIIPI00025115   IPI00911012   IPI00449132   
Protein Interaction databases
DIP (DOE-UCLA)P59780
IntAct (EBI)P59780
FunCoupENSG00000157823
BioGRIDAP3S2
STRING (EMBL)AP3S2
ZODIACAP3S2
Ontologies - Pathways
QuickGOP59780
Ontology : AmiGOGolgi apparatus  intracellular protein transport  anterograde axonal transport  protein transporter activity  AP-3 adaptor complex  cytoplasmic vesicle membrane  intracellular membrane-bounded organelle  anterograde synaptic vesicle transport  axon cytoplasm  
Ontology : EGO-EBIGolgi apparatus  intracellular protein transport  anterograde axonal transport  protein transporter activity  AP-3 adaptor complex  cytoplasmic vesicle membrane  intracellular membrane-bounded organelle  anterograde synaptic vesicle transport  axon cytoplasm  
Pathways : KEGGLysosome   
NDEx NetworkAP3S2
Atlas of Cancer Signalling NetworkAP3S2
Wikipedia pathwaysAP3S2
Orthology - Evolution
OrthoDB10239
GeneTree (enSembl)ENSG00000157823
Phylogenetic Trees/Animal Genes : TreeFamAP3S2
HOVERGENP59780
HOGENOMP59780
Homologs : HomoloGeneAP3S2
Homology/Alignments : Family Browser (UCSC)AP3S2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAP3S2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AP3S2
dbVarAP3S2
ClinVarAP3S2
1000_GenomesAP3S2 
Exome Variant ServerAP3S2
ExAC (Exome Aggregation Consortium)AP3S2 (select the gene name)
Genetic variants : HAPMAP10239
Genomic Variants (DGV)AP3S2 [DGVbeta]
DECIPHERAP3S2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAP3S2 
Mutations
ICGC Data PortalAP3S2 
TCGA Data PortalAP3S2 
Broad Tumor PortalAP3S2
OASIS PortalAP3S2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAP3S2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAP3S2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AP3S2
DgiDB (Drug Gene Interaction Database)AP3S2
DoCM (Curated mutations)AP3S2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AP3S2 (select a term)
intoGenAP3S2
Cancer3DAP3S2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602416   
Orphanet
MedgenAP3S2
Genetic Testing Registry AP3S2
NextProtP59780 [Medical]
TSGene10239
GENETestsAP3S2
Target ValidationAP3S2
Huge Navigator AP3S2 [HugePedia]
snp3D : Map Gene to Disease10239
BioCentury BCIQAP3S2
ClinGenAP3S2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10239
Chemical/Pharm GKB GenePA24863
Clinical trialAP3S2
Miscellaneous
canSAR (ICR)AP3S2 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAP3S2
EVEXAP3S2
GoPubMedAP3S2
iHOPAP3S2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:38:28 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.