| Nomenclature | | HGNC (Hugo) | APBB1 581 |
| Entrez_Gene (NCBI) | APBB1 322 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| Cards | | GeneCards (Weizmann) | APBB1 |
| Ensembl (Hinxton) | ENSG00000166313 [Gene_View] chr11:6416355-6440332 [Contig_View] APBB1 [Vega] |
| AceView (NCBI) | APBB1 |
| Genatlas (Paris) | APBB1 |
| SOURCE (Stanford) | NM_001164 NM_001257319 NM_001257320 NM_001257321 NM_001257322 NM_001257323 NM_001257324 NM_001257325 NM_001257326 NM_145689 |
| Genomic and cartography | | GoldenPath (UCSC) | APBB1 - 11p15.4 chr11:6416355-6440332 - 11p15.4 [Description] (hg19-Feb_2009) |
| Ensembl | APBB1 - 11p15.4 [CytoView] |
| Mapping of homologs : NCBI | APBB1 [Mapview] |
| OMIM | 602709 |
| Gene and transcription |
| Genbank (Entrez) | AF394214 AK293452 AK293550 AK293554 AK293613 |
| RefSeq transcript (SRS) | NM_001164 NM_001257319 NM_001257320 NM_001257321 NM_001257322 NM_001257323 NM_001257324 NM_001257325 NM_001257326 NM_145689 |
| RefSeq transcript (Entrez) | NM_001164 NM_001257319 NM_001257320 NM_001257321 NM_001257322 NM_001257323 NM_001257324 NM_001257325 NM_001257326 NM_145689 |
| RefSeq genomic (SRS) | AC_000143 NC_000011 NC_018922 NG_029615 NT_009237 NW_001838021 NW_004078070 |
| RefSeq genomic (Entrez) | AC_000143 NC_000011 NC_018922 NG_029615 NT_009237 NW_001838021 NW_004078070 |
| Consensus coding sequences : CCDS (NCBI) | APBB1 |
| Cluster EST : Unigene | Hs.372840 [ SRS ] Hs.372840 [ NCBI ] |
| CGAP (NCI) | Hs.372840 |
| Alternative Splicing : Fast-db (Paris) | GSHG0005536 |
| Alternative Splicing Gallery | ENSG00000166313 |
| Gene Expression | APBB1 [ NCBI-GEO ] APBB1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | O00213 (SRS) O00213 (Uniprot) |
| NextProt | O00213 |
| With graphics : InterPro | O00213 |
| Splice isoforms : SwissVar | O00213(Swissvar) |
| Domaine pattern : Prosite (SRS) | PID (PS01179) WW_DOMAIN_1 (PS01159) WW_DOMAIN_2 (PS50020) |
| Domaine pattern : Prosite (Expaxy) | PID (PS01179) WW_DOMAIN_1 (PS01159) WW_DOMAIN_2 (PS50020) |
| Domains : Interpro (SRS) | PH_like_dom PTyr_interaction_dom WW_Rsp5_WWP |
| Domains : Interpro (EBI) | PH_like_dom PTyr_interaction_dom WW_Rsp5_WWP |
| Related proteins : CluSTr | O00213 |
| Domain families : Pfam (SRS) | PID (PF00640) WW (PF00397) |
| Domain families : Pfam (Sanger) | PID (PF00640) WW (PF00397) |
| Domain families : Pfam (NCBI) | pfam00640 pfam00397 |
| Domain families : Smart (EMBL) | PTB (SM00462) WW (SM00456) |
| DMDM | 322 |
| Blocks (Seattle) | O00213 |
| PDB (SRS) | 2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE |
| PDB (PDBSum) | 2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE |
| PDB (IMB) | 2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE |
| PDB (RSDB) | 2E45 2HO2 2IDH 2OEI 3D8D 3D8E 3D8F 3DXC 3DXD 3DXE |
| Human Protein Atlas | ENSG00000166313 |
| HPRD | 04087 |
| IPI | IPI00010843 IPI00783577 IPI00922281 IPI01014694 IPI00383108 IPI01009765 IPI00973991 IPI00979222 IPI00941010 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | O00213 |
| IntAct (EBI) | O00213 |
| FunCoup | ENSG00000166313 |
| REACTOME | APBB1 |
| Protein Interaction Database | 322 |
| BioGRID | APBB1 |
| InParanoid | O00213 |
| Interologous Interaction database | O00213 |
| IntegromeDB | APBB1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | APBB1 |
| SNP (GeneSNP Utah) | APBB1 |
| SNP : HGBase | APBB1 |
| Genetic variants : HAPMAP | APBB1 |
| Somatic Mutations in Cancer : COSMIC | APBB1 |
| CONAN: Copy Number Analysis | APBB1 |
| Mutations and Diseases : HGMD | APBB1 |
| OMIM | 602709 |
| GENETests | 602709 |
| Disease Genetic Association | APBB1 |
| Huge Navigator |
APBB1 [HugePedia] APBB1 [HugeCancerGEM] |
| Genomic Variants | APBB1 APBB1 [DGVbeta] |
| snp3D : Map Gene to Disease | 322 |
| General knowledge |
|---|
| Homologs : HomoloGene | APBB1 |
| Homology/Alignments : Family Browser (UCSC) | APBB1 |
| Phylogenetic Trees/Animal Genes : TreeFam | APBB1 |
| Chemical/Protein Interactions : CTD | 322 |
| Chemical/Pharm GKB Gene | PA24873 |
| Clinical trial | APBB1 |
| Cancer Resource (Charite) | ENSG00000166313 |
| Ontology : AmiGO | beta-amyloid binding beta-amyloid binding neuron migration chromatin binding protein binding nucleus nucleus cytoplasm plasma membrane double-strand break repair transcription, DNA-dependent regulation of transcription, DNA-dependent apoptotic process response to DNA damage stimulus cell cycle arrest signal transduction axonogenesis axon guidance transcription factor binding visual learning response to iron ion nuclear speck lamellipodium extracellular matrix organization negative regulation of cell growth growth cone histone binding presynaptic membrane positive regulation of apoptotic process dendritic spine protein complex histone H4 acetylation synapse postsynaptic membrane negative regulation of neuron differentiation positive regulation of DNA repair negative regulation of S phase of mitotic cell cycle positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter perinuclear region of cytoplasm positive regulation of protein secretion negative regulation of thymidylate synthase biosynthetic process proline-rich region binding |
| Ontology : EGO-EBI | beta-amyloid binding beta-amyloid binding neuron migration chromatin binding protein binding nucleus nucleus cytoplasm plasma membrane double-strand break repair transcription, DNA-dependent regulation of transcription, DNA-dependent apoptotic process response to DNA damage stimulus cell cycle arrest signal transduction axonogenesis axon guidance transcription factor binding visual learning response to iron ion nuclear speck lamellipodium extracellular matrix organization negative regulation of cell growth growth cone histone binding presynaptic membrane positive regulation of apoptotic process dendritic spine protein complex histone H4 acetylation synapse postsynaptic membrane negative regulation of neuron differentiation positive regulation of DNA repair negative regulation of S phase of mitotic cell cycle positive regulation of transcription, DNA-dependent positive regulation of transcription from RNA polymerase II promoter perinuclear region of cytoplasm positive regulation of protein secretion negative regulation of thymidylate synthase biosynthetic process proline-rich region binding |
| Pathways : KEGG | Alzheimer's disease |
| Other databases | | Probes |
|---|
| Litterature | | PubMed | 86 Pubmed reference(s) in Entrez |
| PubGene | APBB1 |
| iHOP | APBB1 |
