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APBB3 (amyloid beta precursor protein binding family B member 3)

Identity

Alias_namesamyloid beta (A4) precursor protein-binding, family B, member 3
Alias_symbol (synonym)FE65L2
Other aliasSRA
HGNC (Hugo) APBB3
LocusID (NCBI) 10307
Atlas_Id 60417
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 140558268 and ends at 140564604 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
APBB3 (5q31.3) / APBB3 (5q31.3)APBB3 (5q31.3) / RASSF4 (10q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APBB3   20708
Cards
Entrez_Gene (NCBI)APBB3  10307  amyloid beta precursor protein binding family B member 3
AliasesFE65L2; SRA
GeneCards (Weizmann)APBB3
Ensembl hg19 (Hinxton)ENSG00000113108 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113108 [Gene_View]  chr5:140558268-140564604 [Contig_View]  APBB3 [Vega]
ICGC DataPortalENSG00000113108
TCGA cBioPortalAPBB3
AceView (NCBI)APBB3
Genatlas (Paris)APBB3
WikiGenes10307
SOURCE (Princeton)APBB3
Genetics Home Reference (NIH)APBB3
Genomic and cartography
GoldenPath hg38 (UCSC)APBB3  -     chr5:140558268-140564604 -  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APBB3  -     5q31.3   [Description]    (hg19-Feb_2009)
EnsemblAPBB3 - 5q31.3 [CytoView hg19]  APBB3 - 5q31.3 [CytoView hg38]
Mapping of homologs : NCBIAPBB3 [Mapview hg19]  APBB3 [Mapview hg38]
OMIM602711   
Gene and transcription
Genbank (Entrez)AB018247 AB049618 AB061224 AB079687 AB094990
RefSeq transcript (Entrez)NM_006051 NM_133172 NM_133173 NM_133174 NM_133175 NM_133176
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APBB3
Cluster EST : UnigeneHs.529449 [ NCBI ]
CGAP (NCI)Hs.529449
Alternative Splicing GalleryENSG00000113108
Gene ExpressionAPBB3 [ NCBI-GEO ]   APBB3 [ EBI - ARRAY_EXPRESS ]   APBB3 [ SEEK ]   APBB3 [ MEM ]
Gene Expression Viewer (FireBrowse)APBB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10307
GTEX Portal (Tissue expression)APBB3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95704   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95704  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95704
Splice isoforms : SwissVarO95704
PhosPhoSitePlusO95704
Domaine pattern : Prosite (Expaxy)PID (PS01179)    WW_DOMAIN_1 (PS01159)    WW_DOMAIN_2 (PS50020)   
Domains : Interpro (EBI)PH_dom-like    PTB/PI_dom    WW_dom   
Domain families : Pfam (Sanger)PID (PF00640)   
Domain families : Pfam (NCBI)pfam00640   
Domain families : Smart (EMBL)PTB (SM00462)  WW (SM00456)  
Conserved Domain (NCBI)APBB3
DMDM Disease mutations10307
Blocks (Seattle)APBB3
PDB (SRS)2DYQ    2YSC   
PDB (PDBSum)2DYQ    2YSC   
PDB (IMB)2DYQ    2YSC   
PDB (RSDB)2DYQ    2YSC   
Structural Biology KnowledgeBase2DYQ    2YSC   
SCOP (Structural Classification of Proteins)2DYQ    2YSC   
CATH (Classification of proteins structures)2DYQ    2YSC   
SuperfamilyO95704
Human Protein AtlasENSG00000113108
Peptide AtlasO95704
HPRD04089
IPIIPI00032785   IPI00218293   IPI00218294   IPI00218296   IPI00967914   IPI01013637   IPI00847152   IPI00968188   IPI01013617   IPI00847297   
Protein Interaction databases
DIP (DOE-UCLA)O95704
IntAct (EBI)O95704
FunCoupENSG00000113108
BioGRIDAPBB3
STRING (EMBL)APBB3
ZODIACAPBB3
Ontologies - Pathways
QuickGOO95704
Ontology : AmiGObeta-amyloid binding  protein binding  nucleus  cytoplasm  cytosol  regulation of transcription, DNA-templated  transcription factor binding  actin cytoskeleton  
Ontology : EGO-EBIbeta-amyloid binding  protein binding  nucleus  cytoplasm  cytosol  regulation of transcription, DNA-templated  transcription factor binding  actin cytoskeleton  
NDEx NetworkAPBB3
Atlas of Cancer Signalling NetworkAPBB3
Wikipedia pathwaysAPBB3
Orthology - Evolution
OrthoDB10307
GeneTree (enSembl)ENSG00000113108
Phylogenetic Trees/Animal Genes : TreeFamAPBB3
HOVERGENO95704
HOGENOMO95704
Homologs : HomoloGeneAPBB3
Homology/Alignments : Family Browser (UCSC)APBB3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPBB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APBB3
dbVarAPBB3
ClinVarAPBB3
1000_GenomesAPBB3 
Exome Variant ServerAPBB3
ExAC (Exome Aggregation Consortium)APBB3 (select the gene name)
Genetic variants : HAPMAP10307
Genomic Variants (DGV)APBB3 [DGVbeta]
DECIPHERAPBB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPBB3 
Mutations
ICGC Data PortalAPBB3 
TCGA Data PortalAPBB3 
Broad Tumor PortalAPBB3
OASIS PortalAPBB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPBB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPBB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APBB3
DgiDB (Drug Gene Interaction Database)APBB3
DoCM (Curated mutations)APBB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APBB3 (select a term)
intoGenAPBB3
Cancer3DAPBB3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602711   
Orphanet
MedgenAPBB3
Genetic Testing Registry APBB3
NextProtO95704 [Medical]
TSGene10307
GENETestsAPBB3
Target ValidationAPBB3
Huge Navigator APBB3 [HugePedia]
snp3D : Map Gene to Disease10307
BioCentury BCIQAPBB3
ClinGenAPBB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10307
Chemical/Pharm GKB GenePA134958636
Clinical trialAPBB3
Miscellaneous
canSAR (ICR)APBB3 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPBB3
EVEXAPBB3
GoPubMedAPBB3
iHOPAPBB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:38:29 CEST 2017

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