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APCS (amyloid P component, serum)

Identity

Alias_symbol (synonym)SAP
PTX2
MGC88159
Other aliasHEL-S-92n
HGNC (Hugo) APCS
LocusID (NCBI) 325
Atlas_Id 60419
Location 1q23.2  [Link to chromosome band 1q23]
Location_base_pair Starts at 159557616 and ends at 159558661 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
APCS (1q23.2) / APCS (1q23.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APCS   584
Cards
Entrez_Gene (NCBI)APCS  325  amyloid P component, serum
AliasesHEL-S-92n; PTX2; SAP
GeneCards (Weizmann)APCS
Ensembl hg19 (Hinxton)ENSG00000132703 [Gene_View]  chr1:159557616-159558661 [Contig_View]  APCS [Vega]
Ensembl hg38 (Hinxton)ENSG00000132703 [Gene_View]  chr1:159557616-159558661 [Contig_View]  APCS [Vega]
ICGC DataPortalENSG00000132703
TCGA cBioPortalAPCS
AceView (NCBI)APCS
Genatlas (Paris)APCS
WikiGenes325
SOURCE (Princeton)APCS
Genetics Home Reference (NIH)APCS
Genomic and cartography
GoldenPath hg19 (UCSC)APCS  -     chr1:159557616-159558661 +  1q23.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APCS  -     1q23.2   [Description]    (hg38-Dec_2013)
EnsemblAPCS - 1q23.2 [CytoView hg19]  APCS - 1q23.2 [CytoView hg38]
Mapping of homologs : NCBIAPCS [Mapview hg19]  APCS [Mapview hg38]
OMIM104770   
Gene and transcription
Genbank (Entrez)BC007039 BC007058 BC070178 BT006750 CR450313
RefSeq transcript (Entrez)NM_001639
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)APCS
Cluster EST : UnigeneHs.507080 [ NCBI ]
CGAP (NCI)Hs.507080
Alternative Splicing GalleryENSG00000132703
Gene ExpressionAPCS [ NCBI-GEO ]   APCS [ EBI - ARRAY_EXPRESS ]   APCS [ SEEK ]   APCS [ MEM ]
Gene Expression Viewer (FireBrowse)APCS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)325
GTEX Portal (Tissue expression)APCS
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02743   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02743  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02743
Splice isoforms : SwissVarP02743
PhosPhoSitePlusP02743
Domaine pattern : Prosite (Expaxy)PENTAXIN (PS00289)   
Domains : Interpro (EBI)ConA-like_dom    Pentaxin    Pentaxin_CS   
Domain families : Pfam (Sanger)Pentaxin (PF00354)   
Domain families : Pfam (NCBI)pfam00354   
Domain families : Smart (EMBL)PTX (SM00159)  
Conserved Domain (NCBI)APCS
DMDM Disease mutations325
Blocks (Seattle)APCS
PDB (SRS)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
PDB (PDBSum)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
PDB (IMB)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
PDB (RSDB)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
Structural Biology KnowledgeBase1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
SCOP (Structural Classification of Proteins)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
CATH (Classification of proteins structures)1GYK    1LGN    1SAC    2A3W    2A3X    2A3Y    2W08    3D5O    3KQR    4AVS    4AVT    4AVV    4AYU   
SuperfamilyP02743
Human Protein AtlasENSG00000132703
Peptide AtlasP02743
HPRD00101
IPIIPI00022391   
Protein Interaction databases
DIP (DOE-UCLA)P02743
IntAct (EBI)P02743
FunCoupENSG00000132703
BioGRIDAPCS
STRING (EMBL)APCS
ZODIACAPCS
Ontologies - Pathways
QuickGOP02743
Ontology : AmiGOcomplement component C1q binding  negative regulation of acute inflammatory response  calcium ion binding  extracellular region  extracellular region  extracellular space  nucleus  protein folding  acute-phase response  carbohydrate binding  extracellular matrix  protein complex  negative regulation by host of viral exo-alpha-sialidase activity  negative regulation by host of viral glycoprotein metabolic process  innate immune response  negative regulation of monocyte differentiation  negative regulation of viral entry into host cell  virion binding  negative regulation of viral process  unfolded protein binding  chaperone-mediated protein complex assembly  negative regulation of wound healing  extracellular exosome  blood microparticle  negative regulation of exo-alpha-sialidase activity  negative regulation of glycoprotein metabolic process  
Ontology : EGO-EBIcomplement component C1q binding  negative regulation of acute inflammatory response  calcium ion binding  extracellular region  extracellular region  extracellular space  nucleus  protein folding  acute-phase response  carbohydrate binding  extracellular matrix  protein complex  negative regulation by host of viral exo-alpha-sialidase activity  negative regulation by host of viral glycoprotein metabolic process  innate immune response  negative regulation of monocyte differentiation  negative regulation of viral entry into host cell  virion binding  negative regulation of viral process  unfolded protein binding  chaperone-mediated protein complex assembly  negative regulation of wound healing  extracellular exosome  blood microparticle  negative regulation of exo-alpha-sialidase activity  negative regulation of glycoprotein metabolic process  
NDEx NetworkAPCS
Atlas of Cancer Signalling NetworkAPCS
Wikipedia pathwaysAPCS
Orthology - Evolution
OrthoDB325
GeneTree (enSembl)ENSG00000132703
Phylogenetic Trees/Animal Genes : TreeFamAPCS
HOVERGENP02743
HOGENOMP02743
Homologs : HomoloGeneAPCS
Homology/Alignments : Family Browser (UCSC)APCS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPCS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APCS
dbVarAPCS
ClinVarAPCS
1000_GenomesAPCS 
Exome Variant ServerAPCS
ExAC (Exome Aggregation Consortium)APCS (select the gene name)
Genetic variants : HAPMAP325
Genomic Variants (DGV)APCS [DGVbeta]
DECIPHER (Syndromes)1:159557616-159558661  ENSG00000132703
CONAN: Copy Number AnalysisAPCS 
Mutations
ICGC Data PortalAPCS 
TCGA Data PortalAPCS 
Broad Tumor PortalAPCS
OASIS PortalAPCS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPCS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPCS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APCS
DgiDB (Drug Gene Interaction Database)APCS
DoCM (Curated mutations)APCS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APCS (select a term)
intoGenAPCS
Cancer3DAPCS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM104770   
Orphanet
MedgenAPCS
Genetic Testing Registry APCS
NextProtP02743 [Medical]
TSGene325
GENETestsAPCS
Huge Navigator APCS [HugePedia]
snp3D : Map Gene to Disease325
BioCentury BCIQAPCS
ClinGenAPCS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD325
Chemical/Pharm GKB GenePA24877
Clinical trialAPCS
Miscellaneous
canSAR (ICR)APCS (select the gene name)
Probes
Litterature
PubMed87 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPCS
EVEXAPCS
GoPubMedAPCS
iHOPAPCS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:54:42 CET 2017

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