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APIP (APAF1 interacting protein)

Identity

Alias_symbol (synonym)CGI-29
Mmrp19
APIP2
Other aliasCGI29
MMRP19
hAPIP
HGNC (Hugo) APIP
LocusID (NCBI) 51074
Atlas_Id 52845
Location 11p13  [Link to chromosome band 11p13]
Location_base_pair Starts at 34882296 and ends at 34916411 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ABTB2 (11p13) / APIP (11p13)APIP (11p13) / C10orf35 (10q22.1)APIP (11p13) / PVT1 (8q24.21)
ABTB2 11p13 / APIP 11p13APIP 11p13 / C10orf35 10q22.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APIP   17581
Cards
Entrez_Gene (NCBI)APIP  51074  APAF1 interacting protein
AliasesAPIP2; CGI-29; CGI29; MMRP19; 
hAPIP
GeneCards (Weizmann)APIP
Ensembl hg19 (Hinxton)ENSG00000149089 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149089 [Gene_View]  chr11:34882296-34916411 [Contig_View]  APIP [Vega]
ICGC DataPortalENSG00000149089
TCGA cBioPortalAPIP
AceView (NCBI)APIP
Genatlas (Paris)APIP
WikiGenes51074
SOURCE (Princeton)APIP
Genetics Home Reference (NIH)APIP
Genomic and cartography
GoldenPath hg38 (UCSC)APIP  -     chr11:34882296-34916411 -  11p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APIP  -     11p13   [Description]    (hg19-Feb_2009)
EnsemblAPIP - 11p13 [CytoView hg19]  APIP - 11p13 [CytoView hg38]
Mapping of homologs : NCBIAPIP [Mapview hg19]  APIP [Mapview hg38]
OMIM612491   
Gene and transcription
Genbank (Entrez)AF088034 AF132963 AK225249 AK226157 AK292648
RefSeq transcript (Entrez)NM_015957
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APIP
Cluster EST : UnigeneHs.447794 [ NCBI ]
CGAP (NCI)Hs.447794
Alternative Splicing GalleryENSG00000149089
Gene ExpressionAPIP [ NCBI-GEO ]   APIP [ EBI - ARRAY_EXPRESS ]   APIP [ SEEK ]   APIP [ MEM ]
Gene Expression Viewer (FireBrowse)APIP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51074
GTEX Portal (Tissue expression)APIP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96GX9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96GX9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96GX9
Splice isoforms : SwissVarQ96GX9
PhosPhoSitePlusQ96GX9
Domains : Interpro (EBI)Aldolase_II/adducin_N    MethylthioRu-1-P_deHdtase_MtnB    Salvage_MtnB_euk   
Domain families : Pfam (Sanger)Aldolase_II (PF00596)   
Domain families : Pfam (NCBI)pfam00596   
Domain families : Smart (EMBL)Aldolase_II (SM01007)  
Conserved Domain (NCBI)APIP
DMDM Disease mutations51074
Blocks (Seattle)APIP
PDB (SRS)4M6R   
PDB (PDBSum)4M6R   
PDB (IMB)4M6R   
PDB (RSDB)4M6R   
Structural Biology KnowledgeBase4M6R   
SCOP (Structural Classification of Proteins)4M6R   
CATH (Classification of proteins structures)4M6R   
SuperfamilyQ96GX9
Human Protein AtlasENSG00000149089
Peptide AtlasQ96GX9
HPRD14725
IPIIPI00549730   IPI00911064   IPI00953224   
Protein Interaction databases
DIP (DOE-UCLA)Q96GX9
IntAct (EBI)Q96GX9
FunCoupENSG00000149089
BioGRIDAPIP
STRING (EMBL)APIP
ZODIACAPIP
Ontologies - Pathways
QuickGOQ96GX9
Ontology : AmiGOprotein binding  cytoplasm  apoptotic process  zinc ion binding  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  identical protein binding  negative regulation of apoptotic process  methylthioribulose 1-phosphate dehydratase activity  protein homotetramerization  pyroptosis  regulation of ERK1 and ERK2 cascade  
Ontology : EGO-EBIprotein binding  cytoplasm  apoptotic process  zinc ion binding  L-methionine salvage from methylthioadenosine  L-methionine salvage from methylthioadenosine  identical protein binding  negative regulation of apoptotic process  methylthioribulose 1-phosphate dehydratase activity  protein homotetramerization  pyroptosis  regulation of ERK1 and ERK2 cascade  
Pathways : KEGGCysteine and methionine metabolism   
NDEx NetworkAPIP
Atlas of Cancer Signalling NetworkAPIP
Wikipedia pathwaysAPIP
Orthology - Evolution
OrthoDB51074
GeneTree (enSembl)ENSG00000149089
Phylogenetic Trees/Animal Genes : TreeFamAPIP
HOVERGENQ96GX9
HOGENOMQ96GX9
Homologs : HomoloGeneAPIP
Homology/Alignments : Family Browser (UCSC)APIP
Gene fusions - Rearrangements
Fusion : MitelmanAPIP/C10orf35 [11p13/10q22.1]  
Fusion : MitelmanAPIP/PVT1 [11p13/8q24.21]  [t(8;11)(q24;p13)]  
Fusion: TCGAABTB2 11p13 APIP 11p13 BRCA
Fusion: TCGAAPIP 11p13 C10orf35 10q22.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPIP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APIP
dbVarAPIP
ClinVarAPIP
1000_GenomesAPIP 
Exome Variant ServerAPIP
ExAC (Exome Aggregation Consortium)APIP (select the gene name)
Genetic variants : HAPMAP51074
Genomic Variants (DGV)APIP [DGVbeta]
DECIPHERAPIP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPIP 
Mutations
ICGC Data PortalAPIP 
TCGA Data PortalAPIP 
Broad Tumor PortalAPIP
OASIS PortalAPIP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPIP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPIP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APIP
DgiDB (Drug Gene Interaction Database)APIP
DoCM (Curated mutations)APIP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APIP (select a term)
intoGenAPIP
Cancer3DAPIP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612491   
Orphanet
MedgenAPIP
Genetic Testing Registry APIP
NextProtQ96GX9 [Medical]
TSGene51074
GENETestsAPIP
Target ValidationAPIP
Huge Navigator APIP [HugePedia]
snp3D : Map Gene to Disease51074
BioCentury BCIQAPIP
ClinGenAPIP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51074
Chemical/Pharm GKB GenePA142672601
Clinical trialAPIP
Miscellaneous
canSAR (ICR)APIP (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPIP
EVEXAPIP
GoPubMedAPIP
iHOPAPIP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:23:59 CEST 2017

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