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APLN (apelin)

Identity

Alias_namesapelin
Alias_symbol (synonym)apelin
XNPEP2
Other aliasAPEL
HGNC (Hugo) APLN
LocusID (NCBI) 8862
Atlas_Id 47581
Location Xq26.1  [Link to chromosome band Xq26]
Location_base_pair Starts at 129645259 and ends at 129654956 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
APLN (Xq26.1) / APLN (Xq26.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APLN   16665
Cards
Entrez_Gene (NCBI)APLN  8862  apelin
AliasesAPEL; XNPEP2
GeneCards (Weizmann)APLN
Ensembl hg19 (Hinxton)ENSG00000171388 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171388 [Gene_View]  chrX:129645259-129654956 [Contig_View]  APLN [Vega]
ICGC DataPortalENSG00000171388
TCGA cBioPortalAPLN
AceView (NCBI)APLN
Genatlas (Paris)APLN
WikiGenes8862
SOURCE (Princeton)APLN
Genetics Home Reference (NIH)APLN
Genomic and cartography
GoldenPath hg38 (UCSC)APLN  -     chrX:129645259-129654956 -  Xq26.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APLN  -     Xq26.1   [Description]    (hg19-Feb_2009)
EnsemblAPLN - Xq26.1 [CytoView hg19]  APLN - Xq26.1 [CytoView hg38]
Mapping of homologs : NCBIAPLN [Mapview hg19]  APLN [Mapview hg38]
OMIM300297   
Gene and transcription
Genbank (Entrez)AB023493 AF086248 AK001855 AK312061 AY358657
RefSeq transcript (Entrez)NM_017413
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APLN
Cluster EST : UnigeneHs.303084 [ NCBI ]
CGAP (NCI)Hs.303084
Alternative Splicing GalleryENSG00000171388
Gene ExpressionAPLN [ NCBI-GEO ]   APLN [ EBI - ARRAY_EXPRESS ]   APLN [ SEEK ]   APLN [ MEM ]
Gene Expression Viewer (FireBrowse)APLN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8862
GTEX Portal (Tissue expression)APLN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULZ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULZ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULZ1
Splice isoforms : SwissVarQ9ULZ1
PhosPhoSitePlusQ9ULZ1
Domains : Interpro (EBI)Apelin   
Domain families : Pfam (Sanger)Apelin (PF15360)   
Domain families : Pfam (NCBI)pfam15360   
Conserved Domain (NCBI)APLN
DMDM Disease mutations8862
Blocks (Seattle)APLN
SuperfamilyQ9ULZ1
Human Protein AtlasENSG00000171388
Peptide AtlasQ9ULZ1
HPRD02246
IPIIPI00010087   IPI00419611   IPI00432374   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULZ1
IntAct (EBI)Q9ULZ1
FunCoupENSG00000171388
BioGRIDAPLN
STRING (EMBL)APLN
ZODIACAPLN
Ontologies - Pathways
QuickGOQ9ULZ1
Ontology : AmiGOG-protein coupled receptor binding  regulation of the force of heart contraction  receptor binding  hormone activity  extracellular region  extracellular space  immune response  signal transduction  lactation  positive regulation of cell proliferation  signaling  positive regulation of heat generation  apelin receptor binding  positive regulation of phosphorylation  drinking behavior  regulation of respiratory gaseous exchange  negative regulation of blood pressure  negative regulation of vasoconstriction  perinuclear region of cytoplasm  positive regulation of corticotropin secretion  positive regulation of corticotropin-releasing hormone secretion  
Ontology : EGO-EBIG-protein coupled receptor binding  regulation of the force of heart contraction  receptor binding  hormone activity  extracellular region  extracellular space  immune response  signal transduction  lactation  positive regulation of cell proliferation  signaling  positive regulation of heat generation  apelin receptor binding  positive regulation of phosphorylation  drinking behavior  regulation of respiratory gaseous exchange  negative regulation of blood pressure  negative regulation of vasoconstriction  perinuclear region of cytoplasm  positive regulation of corticotropin secretion  positive regulation of corticotropin-releasing hormone secretion  
NDEx NetworkAPLN
Atlas of Cancer Signalling NetworkAPLN
Wikipedia pathwaysAPLN
Orthology - Evolution
OrthoDB8862
GeneTree (enSembl)ENSG00000171388
Phylogenetic Trees/Animal Genes : TreeFamAPLN
HOVERGENQ9ULZ1
HOGENOMQ9ULZ1
Homologs : HomoloGeneAPLN
Homology/Alignments : Family Browser (UCSC)APLN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPLN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APLN
dbVarAPLN
ClinVarAPLN
1000_GenomesAPLN 
Exome Variant ServerAPLN
ExAC (Exome Aggregation Consortium)APLN (select the gene name)
Genetic variants : HAPMAP8862
Genomic Variants (DGV)APLN [DGVbeta]
DECIPHERAPLN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPLN 
Mutations
ICGC Data PortalAPLN 
TCGA Data PortalAPLN 
Broad Tumor PortalAPLN
OASIS PortalAPLN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPLN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPLN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch APLN
DgiDB (Drug Gene Interaction Database)APLN
DoCM (Curated mutations)APLN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APLN (select a term)
intoGenAPLN
Cancer3DAPLN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300297   
Orphanet
MedgenAPLN
Genetic Testing Registry APLN
NextProtQ9ULZ1 [Medical]
TSGene8862
GENETestsAPLN
Huge Navigator APLN [HugePedia]
snp3D : Map Gene to Disease8862
BioCentury BCIQAPLN
ClinGenAPLN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8862
Chemical/Pharm GKB GenePA134984493
Clinical trialAPLN
Miscellaneous
canSAR (ICR)APLN (select the gene name)
Probes
Litterature
PubMed193 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPLN
EVEXAPLN
GoPubMedAPLN
iHOPAPLN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:06:15 CEST 2017

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