Atlas of Genetics and Cytogenetics in Oncology and Haematology

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APOA5 (apolipoprotein A5)

Identity

Alias_namesapolipoprotein A-V
Alias_symbol (synonym)RAP3
APOA-V
Other aliasAPOAV
HGNC (Hugo) APOA5
LocusID (NCBI) 116519
Atlas_Id 60424
Location 11q23.3  [Link to chromosome band 11q23]
Location_base_pair Starts at 116789370 and ends at 116792420 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		BUD13 (11q23.3) / APOA5 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)APOA5   17288
Cards
Entrez_Gene (NCBI)APOA5  116519  apolipoprotein A5
AliasesAPOAV; RAP3
GeneCards (Weizmann)APOA5
Ensembl hg19 (Hinxton)ENSG00000110243 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000110243 [Gene_View]  chr11:116789370-116792420 [Contig_View]  APOA5 [Vega]
ICGC DataPortalENSG00000110243
TCGA cBioPortalAPOA5
AceView (NCBI)APOA5
Genatlas (Paris)APOA5
WikiGenes116519
SOURCE (Princeton)APOA5
Genetics Home Reference (NIH)APOA5
Genomic and cartography
GoldenPath hg38 (UCSC)APOA5  -     chr11:116789370-116792420 -  11q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOA5  -     11q23.3   [Description]    (hg19-Feb_2009)
EnsemblAPOA5 - 11q23.3 [CytoView hg19]  APOA5 - 11q23.3 [CytoView hg38]
Mapping of homologs : NCBIAPOA5 [Mapview hg19]  APOA5 [Mapview hg38]
OMIM144650   145750   606368   
Gene and transcription
Genbank (Entrez)AF202889 AF202890 AK292739 AK308047 AK315229
RefSeq transcript (Entrez)NM_001166598 NM_052968
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOA5
Cluster EST : UnigeneHs.283923 [ NCBI ]
CGAP (NCI)Hs.283923
Alternative Splicing GalleryENSG00000110243
Gene ExpressionAPOA5 [ NCBI-GEO ]   APOA5 [ EBI - ARRAY_EXPRESS ]   APOA5 [ SEEK ]   APOA5 [ MEM ]
Gene Expression Viewer (FireBrowse)APOA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116519
GTEX Portal (Tissue expression)APOA5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6Q788   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6Q788  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6Q788
Splice isoforms : SwissVarQ6Q788
PhosPhoSitePlusQ6Q788
Domains : Interpro (EBI)ApoA_E   
Domain families : Pfam (Sanger)Apolipoprotein (PF01442)   
Domain families : Pfam (NCBI)pfam01442   
Conserved Domain (NCBI)APOA5
DMDM Disease mutations116519
Blocks (Seattle)APOA5
SuperfamilyQ6Q788
Human Protein AtlasENSG00000110243
Peptide AtlasQ6Q788
HPRD06966
IPIIPI00465378   IPI00657743   
Protein Interaction databases
DIP (DOE-UCLA)Q6Q788
IntAct (EBI)Q6Q788
FunCoupENSG00000110243
BioGRIDAPOA5
STRING (EMBL)APOA5
ZODIACAPOA5
Ontologies - Pathways
QuickGOQ6Q788
Ontology : AmiGOphospholipid binding  extracellular region  extracellular region  extracellular space  cytosol  triglyceride metabolic process  triglyceride metabolic process  cholesterol biosynthetic process  lipid transport  enzyme activator activity  heparin binding  lipid binding  positive regulation of cholesterol esterification  positive regulation of triglyceride catabolic process  positive regulation of very-low-density lipoprotein particle remodeling  cholesterol binding  cholesterol transporter activity  triglyceride catabolic process  enzyme binding  regulation of intestinal cholesterol absorption  neuron projection regeneration  phosphatidylcholine binding  cholesterol efflux  phospholipid efflux  very-low-density lipoprotein particle  low-density lipoprotein particle  high-density lipoprotein particle  triglyceride-rich lipoprotein particle remodeling  high-density lipoprotein particle assembly  lipase binding  lipoprotein metabolic process  lipoprotein metabolic process  tissue regeneration  chylomicron  cholesterol homeostasis  reverse cholesterol transport  positive regulation of fatty acid biosynthetic process  phosphatidylcholine metabolic process  positive regulation of receptor-mediated endocytosis  low-density lipoprotein particle receptor binding  positive regulation of lipid catabolic process  positive regulation of lipoprotein lipase activity  acylglycerol homeostasis  acylglycerol homeostasis  phosphatidylcholine-sterol O-acyltransferase activator activity  lipase activator activity  lipoprotein lipase activator activity  lipoprotein particle receptor binding  triglyceride homeostasis  triglyceride homeostasis  blood microparticle  
Ontology : EGO-EBIphospholipid binding  extracellular region  extracellular region  extracellular space  cytosol  triglyceride metabolic process  triglyceride metabolic process  cholesterol biosynthetic process  lipid transport  enzyme activator activity  heparin binding  lipid binding  positive regulation of cholesterol esterification  positive regulation of triglyceride catabolic process  positive regulation of very-low-density lipoprotein particle remodeling  cholesterol binding  cholesterol transporter activity  triglyceride catabolic process  enzyme binding  regulation of intestinal cholesterol absorption  neuron projection regeneration  phosphatidylcholine binding  cholesterol efflux  phospholipid efflux  very-low-density lipoprotein particle  low-density lipoprotein particle  high-density lipoprotein particle  triglyceride-rich lipoprotein particle remodeling  high-density lipoprotein particle assembly  lipase binding  lipoprotein metabolic process  lipoprotein metabolic process  tissue regeneration  chylomicron  cholesterol homeostasis  reverse cholesterol transport  positive regulation of fatty acid biosynthetic process  phosphatidylcholine metabolic process  positive regulation of receptor-mediated endocytosis  low-density lipoprotein particle receptor binding  positive regulation of lipid catabolic process  positive regulation of lipoprotein lipase activity  acylglycerol homeostasis  acylglycerol homeostasis  phosphatidylcholine-sterol O-acyltransferase activator activity  lipase activator activity  lipoprotein lipase activator activity  lipoprotein particle receptor binding  triglyceride homeostasis  triglyceride homeostasis  blood microparticle  
Pathways : KEGGPPAR signaling pathway   
NDEx NetworkAPOA5
Atlas of Cancer Signalling NetworkAPOA5
Wikipedia pathwaysAPOA5
Orthology - Evolution
OrthoDB116519
GeneTree (enSembl)ENSG00000110243
Phylogenetic Trees/Animal Genes : TreeFamAPOA5
HOVERGENQ6Q788
HOGENOMQ6Q788
Homologs : HomoloGeneAPOA5
Homology/Alignments : Family Browser (UCSC)APOA5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOA5
dbVarAPOA5
ClinVarAPOA5
1000_GenomesAPOA5 
Exome Variant ServerAPOA5
ExAC (Exome Aggregation Consortium)APOA5 (select the gene name)
Genetic variants : HAPMAP116519
Genomic Variants (DGV)APOA5 [DGVbeta]
DECIPHERAPOA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOA5 
Mutations
ICGC Data PortalAPOA5 
TCGA Data PortalAPOA5 
Broad Tumor PortalAPOA5
OASIS PortalAPOA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOA5
DgiDB (Drug Gene Interaction Database)APOA5
DoCM (Curated mutations)APOA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOA5 (select a term)
intoGenAPOA5
Cancer3DAPOA5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM144650    145750    606368   
Orphanet10944   
MedgenAPOA5
Genetic Testing Registry APOA5
NextProtQ6Q788 [Medical]
TSGene116519
GENETestsAPOA5
Target ValidationAPOA5
Huge Navigator APOA5 [HugePedia]
snp3D : Map Gene to Disease116519
BioCentury BCIQAPOA5
ClinGenAPOA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116519
Chemical/Pharm GKB GenePA24888
Clinical trialAPOA5
Miscellaneous
canSAR (ICR)APOA5 (select the gene name)
Probes
Litterature
PubMed388 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOA5
EVEXAPOA5
GoPubMedAPOA5
iHOPAPOA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:01:35 CEST 2017
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