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APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1)

Identity

Alias_namesapolipoprotein B mRNA editing enzyme
Alias_symbol (synonym)BEDP
CDAR1
APOBEC-1
HEPR
Other alias
HGNC (Hugo) APOBEC1
LocusID (NCBI) 339
Atlas_Id 676
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 7649400 and ends at 7670599 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC1   604
Cards
Entrez_Gene (NCBI)APOBEC1  339  apolipoprotein B mRNA editing enzyme catalytic subunit 1
AliasesAPOBEC-1; BEDP; CDAR1; HEPR
GeneCards (Weizmann)APOBEC1
Ensembl hg19 (Hinxton)ENSG00000111701 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111701 [Gene_View]  chr12:7649400-7670599 [Contig_View]  APOBEC1 [Vega]
ICGC DataPortalENSG00000111701
TCGA cBioPortalAPOBEC1
AceView (NCBI)APOBEC1
Genatlas (Paris)APOBEC1
WikiGenes339
SOURCE (Princeton)APOBEC1
Genetics Home Reference (NIH)APOBEC1
Genomic and cartography
GoldenPath hg38 (UCSC)APOBEC1  -     chr12:7649400-7670599 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOBEC1  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblAPOBEC1 - 12p13.31 [CytoView hg19]  APOBEC1 - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC1 [Mapview hg19]  APOBEC1 [Mapview hg38]
OMIM600130   
Gene and transcription
Genbank (Entrez)AI380263 AI862416 BC096158 BC096159 BC096160
RefSeq transcript (Entrez)NM_001304566 NM_001644 NM_005889
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOBEC1
Cluster EST : UnigeneHs.560 [ NCBI ]
CGAP (NCI)Hs.560
Alternative Splicing GalleryENSG00000111701
Gene ExpressionAPOBEC1 [ NCBI-GEO ]   APOBEC1 [ EBI - ARRAY_EXPRESS ]   APOBEC1 [ SEEK ]   APOBEC1 [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339
GTEX Portal (Tissue expression)APOBEC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41238   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41238  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41238
Splice isoforms : SwissVarP41238
PhosPhoSitePlusP41238
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC1
DMDM Disease mutations339
Blocks (Seattle)APOBEC1
SuperfamilyP41238
Human Protein AtlasENSG00000111701
Peptide AtlasP41238
HPRD02531
IPIIPI00013200   IPI00980356   
Protein Interaction databases
DIP (DOE-UCLA)P41238
IntAct (EBI)P41238
FunCoupENSG00000111701
BioGRIDAPOBEC1
STRING (EMBL)APOBEC1
ZODIACAPOBEC1
Ontologies - Pathways
QuickGOP41238
Ontology : AmiGORNA binding  mRNA binding  cytidine deaminase activity  cytosine deaminase activity  protein binding  nucleoplasm  cytoplasm  RNA processing  mRNA processing  lipid metabolic process  triglyceride metabolic process  response to osmotic stress  enzyme activator activity  zinc ion binding  cytidine deamination  response to zinc ion  response to gamma radiation  cytidine to uridine editing  mRNA modification  AU-rich element binding  protein domain specific binding  cellular response to insulin stimulus  regulation of cell proliferation  lipoprotein biosynthetic process  response to drug  lipoprotein transport  ribonucleoprotein complex binding  positive regulation of catalytic activity  response to ethanol  mRNA stabilization  response to calcium ion  defense response to virus  DNA cytosine deamination  DNA demethylation  negative regulation of triglyceride metabolic process  negative regulation of methylation-dependent chromatin silencing  positive regulation of mRNA modification  
Ontology : EGO-EBIRNA binding  mRNA binding  cytidine deaminase activity  cytosine deaminase activity  protein binding  nucleoplasm  cytoplasm  RNA processing  mRNA processing  lipid metabolic process  triglyceride metabolic process  response to osmotic stress  enzyme activator activity  zinc ion binding  cytidine deamination  response to zinc ion  response to gamma radiation  cytidine to uridine editing  mRNA modification  AU-rich element binding  protein domain specific binding  cellular response to insulin stimulus  regulation of cell proliferation  lipoprotein biosynthetic process  response to drug  lipoprotein transport  ribonucleoprotein complex binding  positive regulation of catalytic activity  response to ethanol  mRNA stabilization  response to calcium ion  defense response to virus  DNA cytosine deamination  DNA demethylation  negative regulation of triglyceride metabolic process  negative regulation of methylation-dependent chromatin silencing  positive regulation of mRNA modification  
NDEx NetworkAPOBEC1
Atlas of Cancer Signalling NetworkAPOBEC1
Wikipedia pathwaysAPOBEC1
Orthology - Evolution
OrthoDB339
GeneTree (enSembl)ENSG00000111701
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC1
HOVERGENP41238
HOGENOMP41238
Homologs : HomoloGeneAPOBEC1
Homology/Alignments : Family Browser (UCSC)APOBEC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC1
dbVarAPOBEC1
ClinVarAPOBEC1
1000_GenomesAPOBEC1 
Exome Variant ServerAPOBEC1
ExAC (Exome Aggregation Consortium)APOBEC1 (select the gene name)
Genetic variants : HAPMAP339
Genomic Variants (DGV)APOBEC1 [DGVbeta]
DECIPHERAPOBEC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOBEC1 
Mutations
ICGC Data PortalAPOBEC1 
TCGA Data PortalAPOBEC1 
Broad Tumor PortalAPOBEC1
OASIS PortalAPOBEC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOBEC1
DgiDB (Drug Gene Interaction Database)APOBEC1
DoCM (Curated mutations)APOBEC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC1 (select a term)
intoGenAPOBEC1
Cancer3DAPOBEC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600130   
Orphanet
MedgenAPOBEC1
Genetic Testing Registry APOBEC1
NextProtP41238 [Medical]
TSGene339
GENETestsAPOBEC1
Huge Navigator APOBEC1 [HugePedia]
snp3D : Map Gene to Disease339
BioCentury BCIQAPOBEC1
ClinGenAPOBEC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339
Chemical/Pharm GKB GenePA24889
Clinical trialAPOBEC1
Miscellaneous
canSAR (ICR)APOBEC1 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC1
EVEXAPOBEC1
GoPubMedAPOBEC1
iHOPAPOBEC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:06:17 CEST 2017

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