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APOBEC2 (apolipoprotein B mRNA editing enzyme catalytic subunit 2)

Identity

Alias_namesapolipoprotein B mRNA editing enzyme
Alias_symbol (synonym)ARCD1
ARP1
Other alias
HGNC (Hugo) APOBEC2
LocusID (NCBI) 10930
Atlas_Id 52755
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 41053201 and ends at 41064891 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC2   605
Cards
Entrez_Gene (NCBI)APOBEC2  10930  apolipoprotein B mRNA editing enzyme catalytic subunit 2
AliasesARCD1; ARP1
GeneCards (Weizmann)APOBEC2
Ensembl hg19 (Hinxton)ENSG00000124701 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124701 [Gene_View]  ENSG00000124701 [Sequence]  chr6:41053201-41064891 [Contig_View]  APOBEC2 [Vega]
ICGC DataPortalENSG00000124701
TCGA cBioPortalAPOBEC2
AceView (NCBI)APOBEC2
Genatlas (Paris)APOBEC2
WikiGenes10930
SOURCE (Princeton)APOBEC2
Genetics Home Reference (NIH)APOBEC2
Genomic and cartography
GoldenPath hg38 (UCSC)APOBEC2  -     chr6:41053201-41064891 +  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOBEC2  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblAPOBEC2 - 6p21.1 [CytoView hg19]  APOBEC2 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC2 [Mapview hg19]  APOBEC2 [Mapview hg38]
OMIM604797   
Gene and transcription
Genbank (Entrez)AF086496 AF161698 AI096570 AK223461 AK300689
RefSeq transcript (Entrez)NM_006789
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOBEC2
Cluster EST : UnigeneHs.555915 [ NCBI ]
CGAP (NCI)Hs.555915
Alternative Splicing GalleryENSG00000124701
Gene ExpressionAPOBEC2 [ NCBI-GEO ]   APOBEC2 [ EBI - ARRAY_EXPRESS ]   APOBEC2 [ SEEK ]   APOBEC2 [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10930
GTEX Portal (Tissue expression)APOBEC2
Human Protein AtlasENSG00000124701-APOBEC2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y235   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y235  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y235
Splice isoforms : SwissVarQ9Y235
PhosPhoSitePlusQ9Y235
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC2
DMDM Disease mutations10930
Blocks (Seattle)APOBEC2
PDB (SRS)2NYT   
PDB (PDBSum)2NYT   
PDB (IMB)2NYT   
PDB (RSDB)2NYT   
Structural Biology KnowledgeBase2NYT   
SCOP (Structural Classification of Proteins)2NYT   
CATH (Classification of proteins structures)2NYT   
SuperfamilyQ9Y235
Human Protein Atlas [tissue]ENSG00000124701-APOBEC2 [tissue]
Peptide AtlasQ9Y235
HPRD07268
IPIIPI00009550   IPI00908686   IPI00983345   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y235
IntAct (EBI)Q9Y235
FunCoupENSG00000124701
BioGRIDAPOBEC2
STRING (EMBL)APOBEC2
ZODIACAPOBEC2
Ontologies - Pathways
QuickGOQ9Y235
Ontology : AmiGORNA binding  cytidine deaminase activity  mRNA processing  zinc ion binding  cytidine deamination  cytidine to uridine editing  mRNA modification  identical protein binding  DNA demethylation  
Ontology : EGO-EBIRNA binding  cytidine deaminase activity  mRNA processing  zinc ion binding  cytidine deamination  cytidine to uridine editing  mRNA modification  identical protein binding  DNA demethylation  
Pathways : KEGGAtrazine degradation   
NDEx NetworkAPOBEC2
Atlas of Cancer Signalling NetworkAPOBEC2
Wikipedia pathwaysAPOBEC2
Orthology - Evolution
OrthoDB10930
GeneTree (enSembl)ENSG00000124701
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC2
HOVERGENQ9Y235
HOGENOMQ9Y235
Homologs : HomoloGeneAPOBEC2
Homology/Alignments : Family Browser (UCSC)APOBEC2
Gene fusions - Rearrangements
Fusion : QuiverAPOBEC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC2
dbVarAPOBEC2
ClinVarAPOBEC2
1000_GenomesAPOBEC2 
Exome Variant ServerAPOBEC2
ExAC (Exome Aggregation Consortium)ENSG00000124701
GNOMAD BrowserENSG00000124701
Genetic variants : HAPMAP10930
Genomic Variants (DGV)APOBEC2 [DGVbeta]
DECIPHERAPOBEC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOBEC2 
Mutations
ICGC Data PortalAPOBEC2 
TCGA Data PortalAPOBEC2 
Broad Tumor PortalAPOBEC2
OASIS PortalAPOBEC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOBEC2
DgiDB (Drug Gene Interaction Database)APOBEC2
DoCM (Curated mutations)APOBEC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC2 (select a term)
intoGenAPOBEC2
Cancer3DAPOBEC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604797   
Orphanet
DisGeNETAPOBEC2
MedgenAPOBEC2
Genetic Testing Registry APOBEC2
NextProtQ9Y235 [Medical]
TSGene10930
GENETestsAPOBEC2
Target ValidationAPOBEC2
Huge Navigator APOBEC2 [HugePedia]
snp3D : Map Gene to Disease10930
BioCentury BCIQAPOBEC2
ClinGenAPOBEC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10930
Chemical/Pharm GKB GenePA24890
Clinical trialAPOBEC2
Miscellaneous
canSAR (ICR)APOBEC2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC2
EVEXAPOBEC2
GoPubMedAPOBEC2
iHOPAPOBEC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:14:27 CEST 2018

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