Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

APOBEC3A (apolipoprotein B mRNA editing enzyme catalytic subunit 3A)

Identity

Alias_namesapolipoprotein B mRNA editing enzyme
Alias_symbol (synonym)ARP3
PHRBN
Other aliasA3A
bK150C2.1
HGNC (Hugo) APOBEC3A
LocusID (NCBI) 200315
Atlas_Id 50116
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39353527 and ends at 39359188 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC3A   17343
Cards
Entrez_Gene (NCBI)APOBEC3A  200315  apolipoprotein B mRNA editing enzyme catalytic subunit 3A
AliasesA3A; ARP3; PHRBN; bK150C2.1
GeneCards (Weizmann)APOBEC3A
Ensembl hg19 (Hinxton)ENSG00000128383 [Gene_View]  chr22:39353527-39359188 [Contig_View]  APOBEC3A [Vega]
Ensembl hg38 (Hinxton)ENSG00000128383 [Gene_View]  chr22:39353527-39359188 [Contig_View]  APOBEC3A [Vega]
ICGC DataPortalENSG00000128383
TCGA cBioPortalAPOBEC3A
AceView (NCBI)APOBEC3A
Genatlas (Paris)APOBEC3A
WikiGenes200315
SOURCE (Princeton)APOBEC3A
Genetics Home Reference (NIH)APOBEC3A
Genomic and cartography
GoldenPath hg19 (UCSC)APOBEC3A  -     chr22:39353527-39359188 +  22q13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APOBEC3A  -     22q13.1   [Description]    (hg38-Dec_2013)
EnsemblAPOBEC3A - 22q13.1 [CytoView hg19]  APOBEC3A - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC3A [Mapview hg19]  APOBEC3A [Mapview hg38]
OMIM607109   
Gene and transcription
Genbank (Entrez)BC126416 BC144146 BI029063 CR456393 CU012950
RefSeq transcript (Entrez)NM_001270406 NM_145699
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)APOBEC3A
Cluster EST : UnigeneHs.226307 [ NCBI ]
CGAP (NCI)Hs.226307
Alternative Splicing GalleryENSG00000128383
Gene ExpressionAPOBEC3A [ NCBI-GEO ]   APOBEC3A [ EBI - ARRAY_EXPRESS ]   APOBEC3A [ SEEK ]   APOBEC3A [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)200315
GTEX Portal (Tissue expression)APOBEC3A
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31941   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP31941  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP31941
Splice isoforms : SwissVarP31941
Catalytic activity : Enzyme3.5.4.- [ Enzyme-Expasy ]   3.5.4.-3.5.4.- [ IntEnz-EBI ]   3.5.4.- [ BRENDA ]   3.5.4.- [ KEGG ]   
PhosPhoSitePlusP31941
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC3A
DMDM Disease mutations200315
Blocks (Seattle)APOBEC3A
PDB (SRS)2M65    4XXO   
PDB (PDBSum)2M65    4XXO   
PDB (IMB)2M65    4XXO   
PDB (RSDB)2M65    4XXO   
Structural Biology KnowledgeBase2M65    4XXO   
SCOP (Structural Classification of Proteins)2M65    4XXO   
CATH (Classification of proteins structures)2M65    4XXO   
SuperfamilyP31941
Human Protein AtlasENSG00000128383
Peptide AtlasP31941
HPRD06168
IPIIPI00013876   IPI01025690   
Protein Interaction databases
DIP (DOE-UCLA)P31941
IntAct (EBI)P31941
FunCoupENSG00000128383
BioGRIDAPOBEC3A
STRING (EMBL)APOBEC3A
ZODIACAPOBEC3A
Ontologies - Pathways
QuickGOP31941
Ontology : AmiGOcytidine deaminase activity  cytidine deaminase activity  protein binding  nucleus  nucleoplasm  cytoplasm  zinc ion binding  cytidine deamination  cytidine deamination  negative regulation of transposition  clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine  negative regulation of viral genome replication  innate immune response  deoxycytidine deaminase activity  defense response to virus  DNA cytosine deamination  DNA cytosine deamination  cellular response to xenobiotic stimulus  DNA demethylation  
Ontology : EGO-EBIcytidine deaminase activity  cytidine deaminase activity  protein binding  nucleus  nucleoplasm  cytoplasm  zinc ion binding  cytidine deamination  cytidine deamination  negative regulation of transposition  clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine  negative regulation of viral genome replication  innate immune response  deoxycytidine deaminase activity  defense response to virus  DNA cytosine deamination  DNA cytosine deamination  cellular response to xenobiotic stimulus  DNA demethylation  
NDEx NetworkAPOBEC3A
Atlas of Cancer Signalling NetworkAPOBEC3A
Wikipedia pathwaysAPOBEC3A
Orthology - Evolution
OrthoDB200315
GeneTree (enSembl)ENSG00000128383
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC3A
HOVERGENP31941
HOGENOMP31941
Homologs : HomoloGeneAPOBEC3A
Homology/Alignments : Family Browser (UCSC)APOBEC3A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC3A
dbVarAPOBEC3A
ClinVarAPOBEC3A
1000_GenomesAPOBEC3A 
Exome Variant ServerAPOBEC3A
ExAC (Exome Aggregation Consortium)APOBEC3A (select the gene name)
Genetic variants : HAPMAP200315
Genomic Variants (DGV)APOBEC3A [DGVbeta]
DECIPHER (Syndromes)22:39353527-39359188  ENSG00000128383
CONAN: Copy Number AnalysisAPOBEC3A 
Mutations
ICGC Data PortalAPOBEC3A 
TCGA Data PortalAPOBEC3A 
Broad Tumor PortalAPOBEC3A
OASIS PortalAPOBEC3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOBEC3A
DgiDB (Drug Gene Interaction Database)APOBEC3A
DoCM (Curated mutations)APOBEC3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC3A (select a term)
intoGenAPOBEC3A
Cancer3DAPOBEC3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607109   
Orphanet
MedgenAPOBEC3A
Genetic Testing Registry APOBEC3A
NextProtP31941 [Medical]
TSGene200315
GENETestsAPOBEC3A
Huge Navigator APOBEC3A [HugePedia]
snp3D : Map Gene to Disease200315
BioCentury BCIQAPOBEC3A
ClinGenAPOBEC3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD200315
Chemical/Pharm GKB GenePA24891
Clinical trialAPOBEC3A
Miscellaneous
canSAR (ICR)APOBEC3A (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC3A
EVEXAPOBEC3A
GoPubMedAPOBEC3A
iHOPAPOBEC3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:52:40 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.