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APOBEC3C (apolipoprotein B mRNA editing enzyme catalytic subunit 3C)

Identity

Alias_namesapolipoprotein B mRNA editing enzyme
Alias_symbol (synonym)APOBEC1L
PBI
bK150C2.3
ARDC2
ARDC4
ARP5
Other aliasA3C
HGNC (Hugo) APOBEC3C
LocusID (NCBI) 27350
Atlas_Id 50033
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39014260 and ends at 39018820 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
APOBEC3C (22q13.1) / MGRN1 (16p13.3)EIF4G2 (11p15.3) / APOBEC3C (22q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC3C   17353
Cards
Entrez_Gene (NCBI)APOBEC3C  27350  apolipoprotein B mRNA editing enzyme catalytic subunit 3C
AliasesA3C; APOBEC1L; ARDC2; ARDC4; 
ARP5; PBI; bK150C2.3
GeneCards (Weizmann)APOBEC3C
Ensembl hg19 (Hinxton)ENSG00000244509 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244509 [Gene_View]  chr22:39014260-39018820 [Contig_View]  APOBEC3C [Vega]
ICGC DataPortalENSG00000244509
TCGA cBioPortalAPOBEC3C
AceView (NCBI)APOBEC3C
Genatlas (Paris)APOBEC3C
WikiGenes27350
SOURCE (Princeton)APOBEC3C
Genetics Home Reference (NIH)APOBEC3C
Genomic and cartography
GoldenPath hg38 (UCSC)APOBEC3C  -     chr22:39014260-39018820 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOBEC3C  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblAPOBEC3C - 22q13.1 [CytoView hg19]  APOBEC3C - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC3C [Mapview hg19]  APOBEC3C [Mapview hg38]
OMIM607750   
Gene and transcription
Genbank (Entrez)AB208979 AF165520 AK094570 AK313272 BC011739
RefSeq transcript (Entrez)NM_014508
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOBEC3C
Cluster EST : UnigeneHs.441124 [ NCBI ]
CGAP (NCI)Hs.441124
Alternative Splicing GalleryENSG00000244509
Gene ExpressionAPOBEC3C [ NCBI-GEO ]   APOBEC3C [ EBI - ARRAY_EXPRESS ]   APOBEC3C [ SEEK ]   APOBEC3C [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27350
GTEX Portal (Tissue expression)APOBEC3C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRW3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRW3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRW3
Splice isoforms : SwissVarQ9NRW3
Catalytic activity : Enzyme3.5.4.- [ Enzyme-Expasy ]   3.5.4.-3.5.4.- [ IntEnz-EBI ]   3.5.4.- [ BRENDA ]   3.5.4.- [ KEGG ]   
PhosPhoSitePlusQ9NRW3
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC3C
DMDM Disease mutations27350
Blocks (Seattle)APOBEC3C
PDB (SRS)3VM8    3VOW   
PDB (PDBSum)3VM8    3VOW   
PDB (IMB)3VM8    3VOW   
PDB (RSDB)3VM8    3VOW   
Structural Biology KnowledgeBase3VM8    3VOW   
SCOP (Structural Classification of Proteins)3VM8    3VOW   
CATH (Classification of proteins structures)3VM8    3VOW   
SuperfamilyQ9NRW3
Human Protein AtlasENSG00000244509
Peptide AtlasQ9NRW3
HPRD09671
IPIIPI00555878   IPI00872929   IPI00879789   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRW3
IntAct (EBI)Q9NRW3
FunCoupENSG00000244509
BioGRIDAPOBEC3C
STRING (EMBL)APOBEC3C
ZODIACAPOBEC3C
Ontologies - Pathways
QuickGOQ9NRW3
Ontology : AmiGORNA binding  protein binding  nucleus  cytoplasm  zinc ion binding  cytidine deamination  negative regulation of transposition  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines  negative regulation of viral genome replication  innate immune response  defense response to virus  DNA demethylation  
Ontology : EGO-EBIRNA binding  protein binding  nucleus  cytoplasm  zinc ion binding  cytidine deamination  negative regulation of transposition  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines  negative regulation of viral genome replication  innate immune response  defense response to virus  DNA demethylation  
NDEx NetworkAPOBEC3C
Atlas of Cancer Signalling NetworkAPOBEC3C
Wikipedia pathwaysAPOBEC3C
Orthology - Evolution
OrthoDB27350
GeneTree (enSembl)ENSG00000244509
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC3C
HOVERGENQ9NRW3
HOGENOMQ9NRW3
Homologs : HomoloGeneAPOBEC3C
Homology/Alignments : Family Browser (UCSC)APOBEC3C
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC3C
dbVarAPOBEC3C
ClinVarAPOBEC3C
1000_GenomesAPOBEC3C 
Exome Variant ServerAPOBEC3C
ExAC (Exome Aggregation Consortium)APOBEC3C (select the gene name)
Genetic variants : HAPMAP27350
Genomic Variants (DGV)APOBEC3C [DGVbeta]
DECIPHERAPOBEC3C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOBEC3C 
Mutations
ICGC Data PortalAPOBEC3C 
TCGA Data PortalAPOBEC3C 
Broad Tumor PortalAPOBEC3C
OASIS PortalAPOBEC3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC3C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOBEC3C
DgiDB (Drug Gene Interaction Database)APOBEC3C
DoCM (Curated mutations)APOBEC3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC3C (select a term)
intoGenAPOBEC3C
Cancer3DAPOBEC3C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607750   
Orphanet
MedgenAPOBEC3C
Genetic Testing Registry APOBEC3C
NextProtQ9NRW3 [Medical]
TSGene27350
GENETestsAPOBEC3C
Huge Navigator APOBEC3C [HugePedia]
snp3D : Map Gene to Disease27350
BioCentury BCIQAPOBEC3C
ClinGenAPOBEC3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27350
Chemical/Pharm GKB GenePA24893
Clinical trialAPOBEC3C
Miscellaneous
canSAR (ICR)APOBEC3C (select the gene name)
Probes
Litterature
PubMed94 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC3C
EVEXAPOBEC3C
GoPubMedAPOBEC3C
iHOPAPOBEC3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:06:18 CEST 2017

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