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APOBEC3F (apolipoprotein B mRNA editing enzyme catalytic subunit 3F)

Identity

Other aliasA3F
ARP8
BK150C2.4.MRNA
KA6
HGNC (Hugo) APOBEC3F
LocusID (NCBI) 200316
Atlas_Id 56665
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39040668 and ends at 39044423 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APOBEC3F (22q13.1) / SBF1 (22q13.33)APOBEC3F (22q13.1) / WDR70 (5p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC3F   17356
Cards
Entrez_Gene (NCBI)APOBEC3F  200316  apolipoprotein B mRNA editing enzyme catalytic subunit 3F
AliasesA3F; ARP8; BK150C2.4.MRNA; KA6
GeneCards (Weizmann)APOBEC3F
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr22:39040668-39044423 [Contig_View]  APOBEC3F [Vega]
TCGA cBioPortalAPOBEC3F
AceView (NCBI)APOBEC3F
Genatlas (Paris)APOBEC3F
WikiGenes200316
SOURCE (Princeton)APOBEC3F
Genetics Home Reference (NIH)APOBEC3F
Genomic and cartography
GoldenPath hg38 (UCSC)APOBEC3F  -     chr22:39040668-39044423 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOBEC3F  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblAPOBEC3F - 22q13.1 [CytoView hg19]  APOBEC3F - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC3F [Mapview hg19]  APOBEC3F [Mapview hg38]
OMIM608993   
Gene and transcription
Genbank (Entrez)AK294810 BC038808 BE888653 BE892372 BG280786
RefSeq transcript (Entrez)NM_001006666 NM_145298
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOBEC3F
Cluster EST : UnigeneHs.659809 [ NCBI ]
CGAP (NCI)Hs.659809
Gene ExpressionAPOBEC3F [ NCBI-GEO ]   APOBEC3F [ EBI - ARRAY_EXPRESS ]   APOBEC3F [ SEEK ]   APOBEC3F [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC3F [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)200316
GTEX Portal (Tissue expression)APOBEC3F
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IUX4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IUX4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IUX4
Splice isoforms : SwissVarQ8IUX4
Catalytic activity : Enzyme3.5.4.- [ Enzyme-Expasy ]   3.5.4.-3.5.4.- [ IntEnz-EBI ]   3.5.4.- [ BRENDA ]   3.5.4.- [ KEGG ]   
PhosPhoSitePlusQ8IUX4
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC3F
DMDM Disease mutations200316
Blocks (Seattle)APOBEC3F
PDB (SRS)3WUS    4IOU    4J4J    5HX4    5HX5   
PDB (PDBSum)3WUS    4IOU    4J4J    5HX4    5HX5   
PDB (IMB)3WUS    4IOU    4J4J    5HX4    5HX5   
PDB (RSDB)3WUS    4IOU    4J4J    5HX4    5HX5   
Structural Biology KnowledgeBase3WUS    4IOU    4J4J    5HX4    5HX5   
SCOP (Structural Classification of Proteins)3WUS    4IOU    4J4J    5HX4    5HX5   
CATH (Classification of proteins structures)3WUS    4IOU    4J4J    5HX4    5HX5   
SuperfamilyQ8IUX4
Peptide AtlasQ8IUX4
IPIIPI00477614   IPI00409765   IPI00419289   
Protein Interaction databases
DIP (DOE-UCLA)Q8IUX4
IntAct (EBI)Q8IUX4
BioGRIDAPOBEC3F
STRING (EMBL)APOBEC3F
ZODIACAPOBEC3F
Ontologies - Pathways
QuickGOQ8IUX4
Ontology : AmiGOP-body  positive regulation of defense response to virus by host  RNA binding  cytidine deaminase activity  protein binding  cytoplasm  zinc ion binding  cytidine deamination  negative regulation of transposition  base conversion or substitution editing  intracellular ribonucleoprotein complex  apolipoprotein B mRNA editing enzyme complex  negative regulation of viral genome replication  innate immune response  negative regulation of single stranded viral RNA replication via double stranded DNA intermediate  negative regulation of viral process  defense response to virus  DNA cytosine deamination  DNA demethylation  
Ontology : EGO-EBIP-body  positive regulation of defense response to virus by host  RNA binding  cytidine deaminase activity  protein binding  cytoplasm  zinc ion binding  cytidine deamination  negative regulation of transposition  base conversion or substitution editing  intracellular ribonucleoprotein complex  apolipoprotein B mRNA editing enzyme complex  negative regulation of viral genome replication  innate immune response  negative regulation of single stranded viral RNA replication via double stranded DNA intermediate  negative regulation of viral process  defense response to virus  DNA cytosine deamination  DNA demethylation  
NDEx NetworkAPOBEC3F
Atlas of Cancer Signalling NetworkAPOBEC3F
Wikipedia pathwaysAPOBEC3F
Orthology - Evolution
OrthoDB200316
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC3F
HOVERGENQ8IUX4
HOGENOMQ8IUX4
Homologs : HomoloGeneAPOBEC3F
Homology/Alignments : Family Browser (UCSC)APOBEC3F
Gene fusions - Rearrangements
Tumor Fusion PortalAPOBEC3F
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC3F [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC3F
dbVarAPOBEC3F
ClinVarAPOBEC3F
1000_GenomesAPOBEC3F 
Exome Variant ServerAPOBEC3F
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP200316
Genomic Variants (DGV)APOBEC3F [DGVbeta]
DECIPHERAPOBEC3F [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOBEC3F 
Mutations
ICGC Data PortalAPOBEC3F 
TCGA Data PortalAPOBEC3F 
Broad Tumor PortalAPOBEC3F
OASIS PortalAPOBEC3F [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC3F  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC3F
BioMutasearch APOBEC3F
DgiDB (Drug Gene Interaction Database)APOBEC3F
DoCM (Curated mutations)APOBEC3F (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC3F (select a term)
intoGenAPOBEC3F
Cancer3DAPOBEC3F(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608993   
Orphanet
DisGeNETAPOBEC3F
MedgenAPOBEC3F
Genetic Testing Registry APOBEC3F
NextProtQ8IUX4 [Medical]
TSGene200316
GENETestsAPOBEC3F
Target ValidationAPOBEC3F
Huge Navigator APOBEC3F [HugePedia]
snp3D : Map Gene to Disease200316
BioCentury BCIQAPOBEC3F
ClinGenAPOBEC3F
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD200316
Chemical/Pharm GKB GenePA24896
Clinical trialAPOBEC3F
Miscellaneous
canSAR (ICR)APOBEC3F (select the gene name)
Probes
Litterature
PubMed185 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC3F
EVEXAPOBEC3F
GoPubMedAPOBEC3F
iHOPAPOBEC3F
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:20 CET 2017

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