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APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic subunit 3G)

Identity

Alias_namesapolipoprotein B mRNA editing enzyme
Alias_symbol (synonym)CEM15
MDS019
dJ494G10.1
FLJ12740
bK150C2.7
Other aliasA3G
ARCD
ARP-9
ARP9
CEM-15
HGNC (Hugo) APOBEC3G
LocusID (NCBI) 60489
Atlas_Id 46621
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 39077005 and ends at 39087743 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
APOBEC3G (22q13.1) / HGSNAT (8p11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOBEC3G   17357
Cards
Entrez_Gene (NCBI)APOBEC3G  60489  apolipoprotein B mRNA editing enzyme catalytic subunit 3G
AliasesA3G; ARCD; ARP-9; ARP9; 
CEM-15; CEM15; MDS019; bK150C2.7; dJ494G10.1
GeneCards (Weizmann)APOBEC3G
Ensembl hg19 (Hinxton)ENSG00000239713 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000239713 [Gene_View]  chr22:39077005-39087743 [Contig_View]  APOBEC3G [Vega]
ICGC DataPortalENSG00000239713
TCGA cBioPortalAPOBEC3G
AceView (NCBI)APOBEC3G
Genatlas (Paris)APOBEC3G
WikiGenes60489
SOURCE (Princeton)APOBEC3G
Genetics Home Reference (NIH)APOBEC3G
Genomic and cartography
GoldenPath hg38 (UCSC)APOBEC3G  -     chr22:39077005-39087743 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)APOBEC3G  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblAPOBEC3G - 22q13.1 [CytoView hg19]  APOBEC3G - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBIAPOBEC3G [Mapview hg19]  APOBEC3G [Mapview hg38]
OMIM607113   
Gene and transcription
Genbank (Entrez)AB266487 AF182420 AK022802 AK092614 AK093635
RefSeq transcript (Entrez)NM_001349436 NM_001349437 NM_001349438 NM_021822
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)APOBEC3G
Cluster EST : UnigeneHs.660143 [ NCBI ]
CGAP (NCI)Hs.660143
Alternative Splicing GalleryENSG00000239713
Gene ExpressionAPOBEC3G [ NCBI-GEO ]   APOBEC3G [ EBI - ARRAY_EXPRESS ]   APOBEC3G [ SEEK ]   APOBEC3G [ MEM ]
Gene Expression Viewer (FireBrowse)APOBEC3G [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)60489
GTEX Portal (Tissue expression)APOBEC3G
Human Protein AtlasENSG00000239713-APOBEC3G [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC16   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HC16  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HC16
Splice isoforms : SwissVarQ9HC16
Catalytic activity : Enzyme3.5.4.- [ Enzyme-Expasy ]   3.5.4.-3.5.4.- [ IntEnz-EBI ]   3.5.4.- [ BRENDA ]   3.5.4.- [ KEGG ]   
PhosPhoSitePlusQ9HC16
Domaine pattern : Prosite (Expaxy)CYT_DCMP_DEAMINASES_1 (PS00903)    CYT_DCMP_DEAMINASES_2 (PS51747)   
Domains : Interpro (EBI)APOBEC/CMP_deaminase_Zn-bd    APOBEC_N    CMP_dCMP_Zn-bd    Cytidine_deaminase-like   
Domain families : Pfam (Sanger)APOBEC_N (PF08210)   
Domain families : Pfam (NCBI)pfam08210   
Conserved Domain (NCBI)APOBEC3G
DMDM Disease mutations60489
Blocks (Seattle)APOBEC3G
PDB (SRS)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
PDB (PDBSum)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
PDB (IMB)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
PDB (RSDB)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
Structural Biology KnowledgeBase2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
SCOP (Structural Classification of Proteins)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
CATH (Classification of proteins structures)2JYW    2KBO    2KEM    3E1U    3IQS    3IR2    3V4J    3V4K    4ROV    4ROW   
SuperfamilyQ9HC16
Human Protein Atlas [tissue]ENSG00000239713-APOBEC3G [tissue]
Peptide AtlasQ9HC16
HPRD06172
IPIIPI00396656   IPI00401132   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC16
IntAct (EBI)Q9HC16
FunCoupENSG00000239713
BioGRIDAPOBEC3G
STRING (EMBL)APOBEC3G
ZODIACAPOBEC3G
Ontologies - Pathways
QuickGOQ9HC16
Ontology : AmiGOP-body  positive regulation of defense response to virus by host  RNA binding  cytidine deaminase activity  protein binding  cytoplasm  cytosol  zinc ion binding  dCTP deaminase activity  cytidine deamination  negative regulation of transposition  base conversion or substitution editing  intracellular ribonucleoprotein complex  apolipoprotein B mRNA editing enzyme complex  protein homodimerization activity  negative regulation of viral genome replication  innate immune response  negative regulation of single stranded viral RNA replication via double stranded DNA intermediate  deoxycytidine deaminase activity  negative regulation of viral process  defense response to virus  DNA cytosine deamination  
Ontology : EGO-EBIP-body  positive regulation of defense response to virus by host  RNA binding  cytidine deaminase activity  protein binding  cytoplasm  cytosol  zinc ion binding  dCTP deaminase activity  cytidine deamination  negative regulation of transposition  base conversion or substitution editing  intracellular ribonucleoprotein complex  apolipoprotein B mRNA editing enzyme complex  protein homodimerization activity  negative regulation of viral genome replication  innate immune response  negative regulation of single stranded viral RNA replication via double stranded DNA intermediate  deoxycytidine deaminase activity  negative regulation of viral process  defense response to virus  DNA cytosine deamination  
NDEx NetworkAPOBEC3G
Atlas of Cancer Signalling NetworkAPOBEC3G
Wikipedia pathwaysAPOBEC3G
Orthology - Evolution
OrthoDB60489
GeneTree (enSembl)ENSG00000239713
Phylogenetic Trees/Animal Genes : TreeFamAPOBEC3G
HOVERGENQ9HC16
HOGENOMQ9HC16
Homologs : HomoloGeneAPOBEC3G
Homology/Alignments : Family Browser (UCSC)APOBEC3G
Gene fusions - Rearrangements
Tumor Fusion PortalAPOBEC3G
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOBEC3G [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOBEC3G
dbVarAPOBEC3G
ClinVarAPOBEC3G
1000_GenomesAPOBEC3G 
Exome Variant ServerAPOBEC3G
ExAC (Exome Aggregation Consortium)ENSG00000239713
GNOMAD BrowserENSG00000239713
Genetic variants : HAPMAP60489
Genomic Variants (DGV)APOBEC3G [DGVbeta]
DECIPHERAPOBEC3G [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAPOBEC3G 
Mutations
ICGC Data PortalAPOBEC3G 
TCGA Data PortalAPOBEC3G 
Broad Tumor PortalAPOBEC3G
OASIS PortalAPOBEC3G [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOBEC3G  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOBEC3G
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOBEC3G
DgiDB (Drug Gene Interaction Database)APOBEC3G
DoCM (Curated mutations)APOBEC3G (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOBEC3G (select a term)
intoGenAPOBEC3G
Cancer3DAPOBEC3G(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607113   
Orphanet
DisGeNETAPOBEC3G
MedgenAPOBEC3G
Genetic Testing Registry APOBEC3G
NextProtQ9HC16 [Medical]
TSGene60489
GENETestsAPOBEC3G
Target ValidationAPOBEC3G
Huge Navigator APOBEC3G [HugePedia]
snp3D : Map Gene to Disease60489
BioCentury BCIQAPOBEC3G
ClinGenAPOBEC3G
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD60489
Chemical/Pharm GKB GenePA24897
Clinical trialAPOBEC3G
Miscellaneous
canSAR (ICR)APOBEC3G (select the gene name)
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOBEC3G
EVEXAPOBEC3G
GoPubMedAPOBEC3G
iHOPAPOBEC3G
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:03:20 CET 2017

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