Atlas of Genetics and Cytogenetics in Oncology and Haematology


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APOC2 (apolipoprotein C-II)

Identity

Alias_namesapolipoprotein C-II
Other aliasAPO-CII
APOC-II
HGNC (Hugo) APOC2
LocusID (NCBI) 344
Atlas_Id 53696
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 45449239 and ends at 45452822 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOC2   609
Cards
Entrez_Gene (NCBI)APOC2  344  apolipoprotein C-II
AliasesAPO-CII; APOC-II
GeneCards (Weizmann)APOC2
Ensembl hg19 (Hinxton)ENSG00000224916 [Gene_View]  chr19:45449239-45452822 [Contig_View]  APOC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000224916 [Gene_View]  chr19:45449239-45452822 [Contig_View]  APOC2 [Vega]
ICGC DataPortalENSG00000224916
TCGA cBioPortalAPOC2
AceView (NCBI)APOC2
Genatlas (Paris)APOC2
WikiGenes344
SOURCE (Princeton)APOC2
Genetics Home Reference (NIH)APOC2
Genomic and cartography
GoldenPath hg19 (UCSC)APOC2  -     chr19:45449239-45452822 +  19q13.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APOC2  -     19q13.32   [Description]    (hg38-Dec_2013)
EnsemblAPOC2 - 19q13.32 [CytoView hg19]  APOC2 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIAPOC2 [Mapview hg19]  APOC2 [Mapview hg38]
OMIM207750   608083   
Gene and transcription
Genbank (Entrez)AA883870 AF113884 AV694494 BC005348 BC065270
RefSeq transcript (Entrez)NM_000483
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_008837 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)APOC2
Cluster EST : UnigeneHs.75615 [ NCBI ]
CGAP (NCI)Hs.75615
Alternative Splicing GalleryENSG00000224916
Gene ExpressionAPOC2 [ NCBI-GEO ]   APOC2 [ EBI - ARRAY_EXPRESS ]   APOC2 [ SEEK ]   APOC2 [ MEM ]
Gene Expression Viewer (FireBrowse)APOC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344
GTEX Portal (Tissue expression)APOC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02655   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02655  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02655
Splice isoforms : SwissVarP02655
PhosPhoSitePlusP02655
Domains : Interpro (EBI)Apo-CII    ApoC-II_domain   
Domain families : Pfam (Sanger)Apo-CII (PF05355)   
Domain families : Pfam (NCBI)pfam05355   
Conserved Domain (NCBI)APOC2
DMDM Disease mutations344
Blocks (Seattle)APOC2
PDB (SRS)1BY6    1I5J    1O8T    1SOH   
PDB (PDBSum)1BY6    1I5J    1O8T    1SOH   
PDB (IMB)1BY6    1I5J    1O8T    1SOH   
PDB (RSDB)1BY6    1I5J    1O8T    1SOH   
Structural Biology KnowledgeBase1BY6    1I5J    1O8T    1SOH   
SCOP (Structural Classification of Proteins)1BY6    1I5J    1O8T    1SOH   
CATH (Classification of proteins structures)1BY6    1I5J    1O8T    1SOH   
SuperfamilyP02655
Human Protein AtlasENSG00000224916
Peptide AtlasP02655
HPRD07457
IPIIPI00021856   
Protein Interaction databases
DIP (DOE-UCLA)P02655
IntAct (EBI)P02655
FunCoupENSG00000224916
BioGRIDAPOC2
STRING (EMBL)APOC2
ZODIACAPOC2
Ontologies - Pathways
QuickGOP02655
Ontology : AmiGOretinoid metabolic process  extracellular region  extracellular region  extracellular space  early endosome  lipid binding  positive regulation of phospholipase activity  positive regulation of triglyceride catabolic process  positive regulation of very-low-density lipoprotein particle remodeling  negative regulation of very-low-density lipoprotein particle clearance  phospholipase activator activity  lipid catabolic process  negative regulation of cholesterol transport  cholesterol efflux  phospholipid efflux  very-low-density lipoprotein particle  low-density lipoprotein particle  intermediate-density lipoprotein particle  spherical high-density lipoprotein particle  triglyceride-rich lipoprotein particle remodeling  chylomicron remodeling  very-low-density lipoprotein particle remodeling  chylomicron remnant clearance  high-density lipoprotein particle clearance  lipoprotein metabolic process  chylomicron  cholesterol homeostasis  protein homodimerization activity  negative regulation of catalytic activity  phospholipase binding  reverse cholesterol transport  positive regulation of fatty acid biosynthetic process  negative regulation of lipid metabolic process  negative regulation of receptor-mediated endocytosis  positive regulation of lipoprotein lipase activity  lipase inhibitor activity  lipoprotein lipase activator activity  positive regulation of phospholipid catabolic process  extracellular exosome  triglyceride homeostasis  
Ontology : EGO-EBIretinoid metabolic process  extracellular region  extracellular region  extracellular space  early endosome  lipid binding  positive regulation of phospholipase activity  positive regulation of triglyceride catabolic process  positive regulation of very-low-density lipoprotein particle remodeling  negative regulation of very-low-density lipoprotein particle clearance  phospholipase activator activity  lipid catabolic process  negative regulation of cholesterol transport  cholesterol efflux  phospholipid efflux  very-low-density lipoprotein particle  low-density lipoprotein particle  intermediate-density lipoprotein particle  spherical high-density lipoprotein particle  triglyceride-rich lipoprotein particle remodeling  chylomicron remodeling  very-low-density lipoprotein particle remodeling  chylomicron remnant clearance  high-density lipoprotein particle clearance  lipoprotein metabolic process  chylomicron  cholesterol homeostasis  protein homodimerization activity  negative regulation of catalytic activity  phospholipase binding  reverse cholesterol transport  positive regulation of fatty acid biosynthetic process  negative regulation of lipid metabolic process  negative regulation of receptor-mediated endocytosis  positive regulation of lipoprotein lipase activity  lipase inhibitor activity  lipoprotein lipase activator activity  positive regulation of phospholipid catabolic process  extracellular exosome  triglyceride homeostasis  
NDEx NetworkAPOC2
Atlas of Cancer Signalling NetworkAPOC2
Wikipedia pathwaysAPOC2
Orthology - Evolution
OrthoDB344
GeneTree (enSembl)ENSG00000224916
Phylogenetic Trees/Animal Genes : TreeFamAPOC2
HOVERGENP02655
HOGENOMP02655
Homologs : HomoloGeneAPOC2
Homology/Alignments : Family Browser (UCSC)APOC2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOC2
dbVarAPOC2
ClinVarAPOC2
1000_GenomesAPOC2 
Exome Variant ServerAPOC2
ExAC (Exome Aggregation Consortium)APOC2 (select the gene name)
Genetic variants : HAPMAP344
Genomic Variants (DGV)APOC2 [DGVbeta]
DECIPHER (Syndromes)19:45449239-45452822  ENSG00000224916
CONAN: Copy Number AnalysisAPOC2 
Mutations
ICGC Data PortalAPOC2 
TCGA Data PortalAPOC2 
Broad Tumor PortalAPOC2
OASIS PortalAPOC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOC2
DgiDB (Drug Gene Interaction Database)APOC2
DoCM (Curated mutations)APOC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOC2 (select a term)
intoGenAPOC2
Cancer3DAPOC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM207750    608083   
Orphanet21337   
MedgenAPOC2
Genetic Testing Registry APOC2
NextProtP02655 [Medical]
TSGene344
GENETestsAPOC2
Huge Navigator APOC2 [HugePedia]
snp3D : Map Gene to Disease344
BioCentury BCIQAPOC2
ClinGenAPOC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD344
Chemical/Pharm GKB GenePA52
Clinical trialAPOC2
Miscellaneous
canSAR (ICR)APOC2 (select the gene name)
Probes
Litterature
PubMed116 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOC2
EVEXAPOC2
GoPubMedAPOC2
iHOPAPOC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:56:08 CET 2017

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