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APOH (apolipoprotein H)

Identity

Alias_namesB2G1
apolipoprotein H (beta-2-glycoprotein I)
Alias_symbol (synonym)BG
Other aliasB2GP1
HGNC (Hugo) APOH
LocusID (NCBI) 350
Atlas_Id 43597
Location 17q24.2  [Link to chromosome band 17q24]
Location_base_pair Starts at 64208147 and ends at 64225556 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MTMR3 (22q12.2) / APOH (17q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)APOH   616
Cards
Entrez_Gene (NCBI)APOH  350  apolipoprotein H
AliasesB2G1; B2GP1; BG
GeneCards (Weizmann)APOH
Ensembl hg19 (Hinxton)ENSG00000091583 [Gene_View]  chr17:64208147-64225556 [Contig_View]  APOH [Vega]
Ensembl hg38 (Hinxton)ENSG00000091583 [Gene_View]  chr17:64208147-64225556 [Contig_View]  APOH [Vega]
ICGC DataPortalENSG00000091583
TCGA cBioPortalAPOH
AceView (NCBI)APOH
Genatlas (Paris)APOH
WikiGenes350
SOURCE (Princeton)APOH
Genetics Home Reference (NIH)APOH
Genomic and cartography
GoldenPath hg19 (UCSC)APOH  -     chr17:64208147-64225556 -  17q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)APOH  -     17q24.2   [Description]    (hg38-Dec_2013)
EnsemblAPOH - 17q24.2 [CytoView hg19]  APOH - 17q24.2 [CytoView hg38]
Mapping of homologs : NCBIAPOH [Mapview hg19]  APOH [Mapview hg38]
OMIM138700   
Gene and transcription
Genbank (Entrez)AK298416 AK313838 BC020703 BC026283 BG566874
RefSeq transcript (Entrez)NM_000042
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_012045 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)APOH
Cluster EST : UnigeneHs.445358 [ NCBI ]
CGAP (NCI)Hs.445358
Alternative Splicing GalleryENSG00000091583
Gene ExpressionAPOH [ NCBI-GEO ]   APOH [ EBI - ARRAY_EXPRESS ]   APOH [ SEEK ]   APOH [ MEM ]
Gene Expression Viewer (FireBrowse)APOH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)350
GTEX Portal (Tissue expression)APOH
Protein : pattern, domain, 3D structure
UniProt/SwissProtP02749   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP02749  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP02749
Splice isoforms : SwissVarP02749
PhosPhoSitePlusP02749
Domaine pattern : Prosite (Expaxy)SUSHI (PS50923)   
Domains : Interpro (EBI)Sushi_2    Sushi_SCR_CCP_dom   
Domain families : Pfam (Sanger)Sushi (PF00084)    Sushi_2 (PF09014)   
Domain families : Pfam (NCBI)pfam00084    pfam09014   
Domain families : Smart (EMBL)CCP (SM00032)  
Domain structure : Prodom (Prabi Lyon)Sushi_2 (PD012422)   
Conserved Domain (NCBI)APOH
DMDM Disease mutations350
Blocks (Seattle)APOH
PDB (SRS)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
PDB (PDBSum)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
PDB (IMB)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
PDB (RSDB)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
Structural Biology KnowledgeBase1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
SCOP (Structural Classification of Proteins)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
CATH (Classification of proteins structures)1C1Z    1G4F    1G4G    1QUB    2KRI    3OP8    4JHS   
SuperfamilyP02749
Human Protein AtlasENSG00000091583
Peptide AtlasP02749
HPRD00728
IPIIPI00298828   
Protein Interaction databases
DIP (DOE-UCLA)P02749
IntAct (EBI)P02749
FunCoupENSG00000091583
BioGRIDAPOH
STRING (EMBL)APOH
ZODIACAPOH
Ontologies - Pathways
QuickGOP02749
Ontology : AmiGOnegative regulation of endothelial cell proliferation  glycoprotein binding  platelet degranulation  protein binding  phospholipid binding  extracellular region  extracellular space  plasma membrane  triglyceride metabolic process  aging  blood coagulation, intrinsic pathway  heparin binding  lipid binding  cell surface  negative regulation of endothelial cell migration  positive regulation of triglyceride catabolic process  negative regulation of angiogenesis  positive regulation of blood coagulation  negative regulation of blood coagulation  extracellular matrix  platelet dense granule lumen  organ regeneration  plasminogen activation  negative regulation of myeloid cell apoptotic process  response to triglyceride  triglyceride transport  very-low-density lipoprotein particle  high-density lipoprotein particle  negative regulation of smooth muscle cell apoptotic process  chylomicron  identical protein binding  positive regulation of lipoprotein lipase activity  regulation of fibrinolysis  negative regulation of fibrinolysis  lipoprotein lipase activator activity  negative regulation of respiratory burst  extracellular exosome  
Ontology : EGO-EBInegative regulation of endothelial cell proliferation  glycoprotein binding  platelet degranulation  protein binding  phospholipid binding  extracellular region  extracellular space  plasma membrane  triglyceride metabolic process  aging  blood coagulation, intrinsic pathway  heparin binding  lipid binding  cell surface  negative regulation of endothelial cell migration  positive regulation of triglyceride catabolic process  negative regulation of angiogenesis  positive regulation of blood coagulation  negative regulation of blood coagulation  extracellular matrix  platelet dense granule lumen  organ regeneration  plasminogen activation  negative regulation of myeloid cell apoptotic process  response to triglyceride  triglyceride transport  very-low-density lipoprotein particle  high-density lipoprotein particle  negative regulation of smooth muscle cell apoptotic process  chylomicron  identical protein binding  positive regulation of lipoprotein lipase activity  regulation of fibrinolysis  negative regulation of fibrinolysis  lipoprotein lipase activator activity  negative regulation of respiratory burst  extracellular exosome  
NDEx NetworkAPOH
Atlas of Cancer Signalling NetworkAPOH
Wikipedia pathwaysAPOH
Orthology - Evolution
OrthoDB350
GeneTree (enSembl)ENSG00000091583
Phylogenetic Trees/Animal Genes : TreeFamAPOH
HOVERGENP02749
HOGENOMP02749
Homologs : HomoloGeneAPOH
Homology/Alignments : Family Browser (UCSC)APOH
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAPOH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)APOH
dbVarAPOH
ClinVarAPOH
1000_GenomesAPOH 
Exome Variant ServerAPOH
ExAC (Exome Aggregation Consortium)APOH (select the gene name)
Genetic variants : HAPMAP350
Genomic Variants (DGV)APOH [DGVbeta]
DECIPHER (Syndromes)17:64208147-64225556  ENSG00000091583
CONAN: Copy Number AnalysisAPOH 
Mutations
ICGC Data PortalAPOH 
TCGA Data PortalAPOH 
Broad Tumor PortalAPOH
OASIS PortalAPOH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAPOH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDAPOH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch APOH
DgiDB (Drug Gene Interaction Database)APOH
DoCM (Curated mutations)APOH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)APOH (select a term)
intoGenAPOH
Cancer3DAPOH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138700   
Orphanet
MedgenAPOH
Genetic Testing Registry APOH
NextProtP02749 [Medical]
TSGene350
GENETestsAPOH
Huge Navigator APOH [HugePedia]
snp3D : Map Gene to Disease350
BioCentury BCIQAPOH
ClinGenAPOH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD350
Chemical/Pharm GKB GenePA24903
Clinical trialAPOH
Miscellaneous
canSAR (ICR)APOH (select the gene name)
Probes
Litterature
PubMed210 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAPOH
EVEXAPOH
GoPubMedAPOH
iHOPAPOH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:52:42 CEST 2017

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